If you're looking for settings, you're in the wrong place. Timber is controlled 100% in your theme (or plugin). For more information on how to do that, read on!

Documentaion

Read an introduction to Timber on WP Mayor
You'll be using Twig to acutally write the HTML for your files. I highly recommend the "Twig for Template Designers" page in their documentation
The Timber Wiki has the complete documentation. But specifically, you might want to check out the 'Cookbooks' for images, text, Advanced Custom Fields and WordPress core/plugin integration
I also produced a series of screencasts (you can watch the first one below) on re-writing Timber into an existing theme.

Getting Started

This is a quick getting-started guide to using Timber in your theme. It requires a solid knowledge of HTML and a basic understanding of PHP.

Method 1: I have an existing theme I want to use with Timber

In that case, use your favorite text editor to open up {{home_file.name}} inside of {{home_file.location}}. This is the file that powers your homepage. If you're working off your server, you'll need to use an FTP program like Transmit or Cyberduck.

Cool, watch this!

(You can fast-forward to about 1:20 after some of the install talk)

Method 2: Starting from scratch!

Great, nothing like a fresh start. Navigate to {{timber_base}}. Inside you should see a timber-starter-theme folder. Grab this and copy/drag it into /wp-content/themes. Rename it to something good.