import { MobxPromise } from 'cbioportal-frontend-commons';
import { GenomeNexusAPI, VariantAnnotation } from 'genome-nexus-ts-api-client';
import { CuratedGene, SomaticIndicatorQueryResp, OncoKbAPI } from 'oncokb-ts-api-client';
import { MutationMapperDataFetcher } from 'react-mutation-mapper';
export interface IVariantStoreConfig {
    variant: string;
}
export declare class VariantStore {
    variantId: string;
    queryString: string;
    query: any;
    genomeNexusClient: GenomeNexusAPI;
    oncokbClient: OncoKbAPI;
    mutationMapperDataFetcher: MutationMapperDataFetcher | undefined;
    variant: string;
    selectedTranscript: string;
    isoformOverrideSource: string;
    readonly annotation: import("cbioportal-frontend-commons").MobxPromiseUnionType<VariantAnnotation>;
    readonly oncokbData: MobxPromise<SomaticIndicatorQueryResp>;
    readonly oncokbGenes: import("cbioportal-frontend-commons").MobxPromiseUnionTypeWithDefault<CuratedGene[]>;
    readonly oncokbGenesMap: import("cbioportal-frontend-commons").MobxPromiseUnionTypeWithDefault<{
        [hugoSymbol: string]: CuratedGene;
    }>;
    readonly isAnnotatedSuccessfully: import("cbioportal-frontend-commons").MobxPromiseUnionType<boolean>;
    get mutationMapperStore(): import("react-mutation-mapper/dist/store/DefaultMutationMapperStore").default<import("cbioportal-utils").Mutation> | undefined;
    constructor(variantId: string, queryString: string, genomeNexusClient?: GenomeNexusAPI, oncoKbClient?: OncoKbAPI, mutationMapperDataFetcher?: MutationMapperDataFetcher);
    get annotationSummary(): import("genome-nexus-ts-api-client").VariantAnnotationSummary | undefined;
}