import * as React from 'react';
import { VariantStore } from '../../store/VariantStore';
import { GenomeNexusAPI } from 'genome-nexus-ts-api-client';
import { OncoKbAPI } from 'oncokb-ts-api-client';
import { MutationMapperDataFetcher } from 'react-mutation-mapper/dist/model/MutationMapperDataFetcher';
interface IVariantProps {
    variant: string;
    store?: VariantStore;
    mainLoadingIndicator?: JSX.Element;
    genomeNexusClient?: GenomeNexusAPI;
    oncoKbClient?: OncoKbAPI;
    mutationMapperDataFetcher?: MutationMapperDataFetcher;
}
export declare function initDefaultVariantStore(props: IVariantProps): VariantStore;
declare class Variant extends React.Component<IVariantProps> {
    constructor(props: IVariantProps);
    render(): React.ReactNode;
    protected get variantStore(): VariantStore;
    private get myVariantInfo();
    private get clinvar();
    private get signalAnnotation();
    private get oncokb();
    private get variantAnnotation();
    get isCanonicalTranscriptSelected(): boolean | undefined;
    protected get isLoading(): boolean;
    protected get loadingIndicator(): JSX.Element;
    get allValidTranscripts(): string[];
    private setActiveTranscript;
    private onTranscriptSelect;
}
export default Variant;