TGF-Beta

A signaling network involved in growth, proliferation, apoptosis, and differentiation involving the activation of TGFβ receptors by the cytokine TGFβ that leads to the activation of gene transcription by SMADs.

--NODE_NAME	NODE_ID	NODE_TYPE	PARENT_ID	POSX	POSY--
SMAD2	0qBZliXOfmft	GENE	Xkk8SKlafmfn	335	410
SMAD	Xkk8SKlafmfn	FAMILY	-1	424	446
Activin ligands	t_Q1Nr-BfmfR	GENE	-1	509	146
ACVR2B	9Ev1i-2HfmfX	GENE	boabbY81fmfT	508	307
TGFBR	fXKkJObYfmfb	FAMILY	-1	329	277
ACVR2A	_sm7432ofmfV	GENE	boabbY81fmfT	509	244
SMAD3	gepyfePvfmfz	GENE	Xkk8SKlafmfn	514	410
TGFBR2	DOJnFoHNfmfi	GENE	fXKkJObYfmfb	329	311
TGFB ligands	gOOpkueqfmfM	GENE	-1	329	146
ACVR2	boabbY81fmfT	FAMILY	-1	508	275
TGFBR1	Sb4zGrL3fmfe	GENE	fXKkJObYfmfb	329	244
Proliferation, stem/progenitor phenotype	A7jMDR2Mfmf-	PROCESS	-1	427	588
SMAD4	OKApI7Qwfmf4	GENE	Xkk8SKlafmfn	428	483

--EDGE_ID	SOURCE	TARGET	EDGE_TYPEINTERACTION_PUBMED_ID
7FzJ455ZfmgP	boabbY81fmfT	Xkk8SKlafmfn	ACTIVATES	
WEH0_CRqfmgL	fXKkJObYfmfb	Xkk8SKlafmfn	ACTIVATES	
hnOBi-Z1fmgI	t_Q1Nr-BfmfR	boabbY81fmfT	ACTIVATES	
Ax3S1Kd8fmgE	gOOpkueqfmfM	fXKkJObYfmfb	ACTIVATES