HIPPO

Involved in the control of organ size. Central to this pathway is the regulation of the transcription co-activators YAP/TAZ that promote the transcription of genes involved in cell proliferation.

--NODE_NAME	NODE_ID	NODE_TYPE	PARENT_ID	POSX	POSY--
HRAS	7o723KjtxLw3	GENE	m8n8vtNexLwr	322	183
NF1	CoRREfZLxLxE	GENE	-1	399	270
Survival	PwPgvbNpxLvq	PROCESS	-1	791	584
RAS	zoIJL9SXxLvs	FAMILY	-1	505	98
FGFR3	xdJHuZOJxLvx	GENE	zoIJL9SXxLvs	272	98
ERBB2	2TufgUnDxLvu	GENE	zoIJL9SXxLvs	584	98
TSC2	PrCzkSRAxLwV	GENE	NIuPl9Z4xLwO	503	496
PTEN	sYk-4hLPxLvn	GENE	-1	860	184
STK11	lFDvCMmBxLv9	GENE	-1	317	469
INPP4B	GLEvKwzFxLwB	GENE	-1	804	266
MTOR	ICScCD_7xLwH	GENE	-1	722	470
Proliferation	uwFqE9I9xLwk	PROCESS	-1	665	584
RAS	m8n8vtNexLwr	FAMILY	-1	399	183
NRAS	gJxmCdGKxLwx	GENE	m8n8vtNexLwr	476	183
ERBB3	MzpcdmxYxLv6	GENE	zoIJL9SXxLvs	739	98
TSC1	RWyL5pe9xLwd	GENE	NIuPl9Z4xLwO	503	444
TSC	NIuPl9Z4xLwO	FAMILY	-1	503	470
PIK3CA	iq8nE1OMxLvj	GENE	-1	658	184
AKT	TiUbnalZxLw_	GENE	-1	659	349
EGFR	5XuhH2Y3xLv2	GENE	zoIJL9SXxLvs	429	98

--EDGE_ID	SOURCE	TARGET	EDGE_TYPEINTERACTION_PUBMED_ID
sFy4CeNZxLxT	sYk-4hLPxLvn	iq8nE1OMxLvj	INHIBITS	
YpeP_yDkxLxQ	TiUbnalZxLw_	NIuPl9Z4xLwO	INHIBITS	
t2QHaOQlxLxX	NIuPl9Z4xLwO	ICScCD_7xLwH	INHIBITS	
--0Bl7NmxLxb	m8n8vtNexLwr	iq8nE1OMxLvj	ACTIVATES	
TihuxwDexLxR	GLEvKwzFxLwB	iq8nE1OMxLvj	INHIBITS	
M4uM8zkMxLxZ	lFDvCMmBxLv9	NIuPl9Z4xLwO	ACTIVATES	
JGhy8m8UxLxN	zoIJL9SXxLvs	m8n8vtNexLwr	ACTIVATES	
rQyUZobSxLxf	ICScCD_7xLwH	uwFqE9I9xLwk	ACTIVATES	
t_83aGiOxLxc	ICScCD_7xLwH	PwPgvbNpxLvq	ACTIVATES	
1Jm9fDfkxLxV	iq8nE1OMxLvj	TiUbnalZxLw_	ACTIVATES	
J7C0UYeQxLxK	CoRREfZLxLxE	m8n8vtNexLwr	INHIBITS