import type { Molecule } from 'openchemlib';
export interface ApplyFragmentLabelsOptions {
    /**
     * Algorithm to use for substructure searching and matching the fragment to the molecule.
     * overlapping: create list not containing multiple matches sharing exactly the same atoms
     * firstMatch: create matchList with just one match
     * separated: create list of all non-overlapping matches / not optimized for maximum match count
     * rigorous: create list of all possible matches neglecting any symmetries
     * unique: create list of all distinguishable matches considering symmetries
     * @default 'overlapping'
     */
    algorithm?: 'firstMatch' | 'separated' | 'overlapping' | 'rigorous' | 'unique';
    prefix?: string;
    suffix?: string;
}
/**
 * Applies fragment labels from a fragment molecule to a target molecule. This method is in
 * place and modifies the target molecule directly.
 * @param molecule - The target molecule to which fragment labels will be applied.
 * @param fragment - The fragment molecule containing the labels to apply.
 * @param options
 * @returns The number of matches found
 */
export declare function applyFragmentLabels(molecule: Molecule, fragment: Molecule, options?: ApplyFragmentLabelsOptions): number;
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