/**
 * This function will add missing chiral bonds on carbons ensure that all enantiotopic
 * or diastereotopic atoms can be identified uniquely
 * @param {import('openchemlib').Molecule} molecule
 * @param {object} [options={}]
 * @param {number} [options.esrType=Molecule.cESRTypeAnd]
 * @param {boolean} [options.atLeastThreeAtoms=true] - if true, only carbons with at least three atoms will be considered
 */
export function ensureHeterotopicChiralBonds(molecule: import("openchemlib").Molecule, options?: {
    esrType?: number | undefined;
    atLeastThreeAtoms?: boolean | undefined;
}): void;
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