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| Is Your Signal Truly Apoptosis? |
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| Modern cell death research faces challenges including apoptosis misclassification, false-positive signals, and limited data robustness. Multi-assay validation helps improve result confidence. |
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Explore Apoptosis Solutions
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Empower Your Research with Elabscience®
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From cell isolation and antibody solutions to functional assays, we provide tools that
support every step of your cancer research workflow. We look forward to meeting you in person at AACR
and discuss how we can support your research. |
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Unreliable ELISA results? You're not alone. Small errors in pipetting, washing, or timing
can ruin your entire assay. Watch step-by-step ELISA videos to improve accuracy and
reproducibility. |
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Watch & Fix My ELISA Workflow
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Metabolic Atlas |
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Cellular Energy Networks from Nutrient Metabolism to Disease Mechanisms |
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This campaign covers the full Elabscience® Metabolism Assay Kit portfolio. |
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View All Metabolism Assays
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Contact your local Elabscience® distributor or sales representative for campaign details and ordering assistance.
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| Tumor immunology research often requires multiple experimental approaches to connect immune phenotypes, metabolic changes, and cellular functions. To support these interconnected workflows, we published the "One-Stop Solutions for Tumor Immunology Research" guide. It presents a closed-loop research solution covering: |
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In the guide,it also highlights emerging research areas, including immunometabolic reprogramming, STING–cGAS signaling, tumor-associated macrophage reprogramming, immune checkpoint combinations, CAR-T optimization, regulated cell death, and extracellular vesicle engineering. |
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Download the Tumor Immunology Research Guide
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Trusted by Researchers Worldwide |
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Elabscience's products have helped over 34,063 papers be published in SCI journals, covering many top journals like Nature Medicine, Nature, Cell, Immunity, Molecular Cancer, etc. |
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View All Publications
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| Product Features |
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No red blood cell lysis treatment is required for samples, ensuring better cell viability.
No stimulation involved; target cells are isolated without antibody or magnetic bead labeling, so cell status remains unaffected.
High purity achieved, with post-sorting cell purity greater than 95%.
No separation columns are needed for isolation.
Short experimental duration, with negative cell sorting completed in as little as 15 minutes.
Suitable for sorting both fresh human PBMC samples and cryopreserved PBMC samples.
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Get More Details
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Data Demonstration
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Fig. 1. Monocyte（Lineage-（CD3,CD45R,CD117,CD170,NK1.1）CD11b+Ly6G-Ly6Chi/lo) were isolated from the Bone marrow cells of C57BL/6 mice, and were stained with APC Anti-Mouse CD3 Antibody[17A2](E-AB-F1013E)、APC Anti-Mouse CD45R (B220) Antibody[RA3-6B2](AN00428E)、APC Anti-Mouse CD117/c-Kit Antibody[2B8](E-AB-F1092E)/APC Anti-Mouse CD170 Antibody[S17007L](AN00629E)/APC Anti-Mouse CD161/NK1.1 Antibody[PK136](E-AB-F0987E)/PE Anti-Mouse/Human CD11b Antibody[M1/70](E-AB-F1081D)/Elab Fluor®Violet 450 Anti-Mouse Ly6G Antibody[1A8](E-AB-F1108Q) and FITC Anti-Mouse Ly6C Antibody[Monts 1](E-AB-F1121C). The purities of start and final isolated fractions were 17.75% and 97.41%, respectively.
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Fig. 2. Sorting and Purity Validation of NK Cells from Human Peripheral Blood PBMCs. As shown in the figure above, flow cytometric analysis of NK cells purity before and after sorting revealed proportions of 15.82% and 95.39%, respectively.
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Product Introduction
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Live‑Cell Imaging, Ultra‑Low Background, True Functional Readout
Lysosomal Activity Fluorometric Assay Kit (E-BC-F202) |
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| Product Features |
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• Add dye directly to live cells, image in 1‑6 h, no lysis or sectioning required
• Self‑quenching probe ensures ultra‑low background and high S/N ratio
• Detects true proteolytic activity, not pH‑dependent
• Narrow emission spectrum allows multiplexing with other dyes
• Excellent photostability and chemical stability for long‑term observation
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| Data Validation |
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| Figure 1. Bafilomycin A1‑treated cells show markedly reduced red fluorescence, indicating decreased lysosomal activity. |
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| Get More Details |
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High‑Specificity, Real‑Time Quantification
Singlet Oxygen(1O2) Fluorometric Assay Kit (E-BC-F062) |
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| Product Features |
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• High specificity for 1O2, minimal interference from other ROS
• Real‑time quantitative detection in live cells
• Compatible with flow cytometry and fluorescence microscopy
• Simple protocol with reliable and reproducible results
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| Data Validation |
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| Figure 2. H2O2‑stimulated cells exhibit significantly increased green fluorescence, indicating elevated 1O2 levels. |
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| Get More Details |
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What You'll Get
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●Crosstalk across programmed cell death pathways
●Signaling architecture and pathway convergence
●Mechanisms driving cellular fate decisions
●Translational relevance in disease and therapy
●Digital Certificate of Participation
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Learn more
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Secure Your Spot |
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Cell Death Atlas: A Holistic View of Cell Death Pathways
Thursday, Jun 18, 2026
12:00 CEST (Berlin, UTC+2) | 14:00 GST (Dubai, UTC+4) | 15:30 IST (New Delhi, UTC +5:30) | 06:00 EDT (New York, UTC-4) | 18:00 CST (Beijing, UTC +8)
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Book and Register Here
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Build a Reliable Multi-Assay Apoptosis Workflow |
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1. Early apoptosis
Detect phosphatidylserine exposure with high sensitivity
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2. Mitochondrial dysfunction
Monitor mitochondrial membrane potential changes
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Annexin V Kits |
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JC-1 Assays |
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3. Caspase activation
Validate apoptosis signaling activation
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4. Late apoptosis
Confirm DNA fragmentation in cells and tissues
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Caspase Assays |
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TUNEL Kits |
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Supporting High-Impact Apoptosis Research |
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Elabscience apoptosis-related products have been cited in 3,000+ publications in leading journals, including:
●Nature Aging
●Cell Research
●Bioactive Materials
Helping researchers achieve reliable apoptosis analysis with validated assays and reproducible results.
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Explore Research Applications
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| Designed for Multicolor Panel Flexibility, These Antibodies Offer: |
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More FCM experimental panel design options
Lower background interference in FCM staining with optimized fluorescence coupling technique
Good separation effect across multiple concentration gradientss
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| New Indicators Introduction (Paticial) |
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Immunotherapy for Hepatocellular Carcinoma Research: Human TCR Vβ7.1
Autoimmune Diseases Research: Human TCR Vβ1
Auxiliary Diagnosis of Tumors: Human CD151
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| Human TCR Vβ7.1 |
Human TCR Vβ1 |
Human CD151 |
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Learn More
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Learn More
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Learn More
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New Product Highlights
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•Streamlined & High-Throughput
Nitric Oxide (NO) Colorimetric Assay Kit (E-BC-K817-M)
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Uses an innovative chemical reduction method enabling direct microplate reading, no transfer,
no centrifugation. Ideal for high-throughput NO quantification in diverse samples.
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Get More Details
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•Live-Cell Real-Time Monitoring
Nitric Oxide (NO) Fluorometric Assay Kit (E-BC-F021)
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Features DAF-FM DA fluorescent probe to directly detect intracellular NO in living cells,
perfect for dynamic cell biology studies.
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Get More Details
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| Product Features |
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• Simple & Efficient: One-step microplate assay
• High Sensitivity & Wide Linear Range: 0.46–100 μmol/L
• Broad Sample Compatibility: Serum, plasma, urine, tissue, cells
• Total NO Measurement: Quantifies NO3-+NO2- for complete metabolic insight
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| Data Demonstration |
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Accurate Recovery of Nitrate & Nitrite Standards
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Reliable Detection in
Raw 264.7 Cells (M1 vs M0)
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| We offer more NO detection products with high sensitivity and specificity, covering various sample types and platforms. |
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Discover More NO Detection Products
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Recombinant Proteins for Functional Research
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4,000+ high-quality proteins across key research areas
Includes cytokines, growth factors, immune checkpoints, CD antigens & more
High bioactivity for cell culture, signaling, and assay development
Reliable supply for screening, validation, and translational research
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Designed for immunology, oncology, stem cell, and drug discovery studies.
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Explore 4,000+ Recombinant Proteins Now
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Purified Antibodies for Flow Cytometry
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Amplify weak signals via indirect staining for low-abundance targets & rare cells
Enables user-defined fluorophore conjugation for flexible multicolor panel design
Preserve cell health in live cell sorting & functional assays
Delivers high specificity, high sensitivity, and excellent lot-to-lot consistency
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Backed by Elabscience quality:
>98% purity | High specificity | Exceptional consistency & stability
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Built for complex panels, novel targets, and high-throughput workflows.
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Upgrade Your Flow Cytometry Performance
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Rabbit Monoclonal Antibodies
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Detect challenging & low-abundance targets with high-affinity binding
Recognize unique epitopes often missed by mouse mAbs
Achieve ultra-low cross-reactivity in complex samples
Sequence-verified antibodies ensure lot-to-lot consistency and reproducibility
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Backed by advanced rabbit monoclonal technology:
High specificity | Superior signal-to-noise | 100% lot consistency | Ethical in vitro production
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Ideal for IHC, IF, IP, FCM and research requiring high sensitivity & precision.
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Explore Rabbit Monoclonal Antibodies Now
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Keywords: Calcific Aortic Valve Disease(CAVD), cGMP-PKG Signaling, ULK1-mediated Autophagy |
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This study first demonstrates the protective role of the cGMP-PKG pathway in calcific aortic
valve disease (CAVD). CAVD patients show reduced serum cGMP and suppressed PKG signaling.
Activating cGMP-PKG, especially with vericiguat, alleviates valve calcification, while PKGI
loss aggravates it. Mechanistically, PKGI directly phosphorylates ULK1 at Ser556 to activate
autophagy, improving mitochondrial function and inhibiting osteogenic differentiation. These
findings suggest that vericiguat, an oral drug already used for heart failure, could be
repurposed for CAVD treatment.
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Serum cGMP, VIC mitochondrial membrane potential (JC-1), and ATP content were measured using Elabscience® cGMP(Cyclic GMP) ELISA Kit, Mitochondrial Membrane Potential Assay Kit (with JC-1), and ATP Colorimetric Assay Kit (Enzyme Method), respectively. |
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Must-Read Cancer Research Insights for AACR 2026
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Why Subset Precision Matters？ |
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Precision where it counts. Whether you are studying functional differentiation, cell
exhaustion, or memory persistence, the purity of your starting population dictates the
integrity of your results. EasySort™ cell isolation kits ensures your downstream data
reflects true cellular biology.
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Advantages of EasySort™ Cell Isolation Kits |
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Engineered for speed and cell viability, EasySort™ cell isolation kits provide:
● Superior Purity & Recovery: Optimized for consistent, high-yield results across diverse subsets.
● Rapid Workflow: Go from sample to isolated cells in just 14–18 minutes.
● Physiological Integrity: Gentle, nagative
isolation-based processing keeps cells "experment-ready" for sensitive functional assays and flow cytometry.
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Learn More
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Claim Your Free EasySort™ Evaluation Kit |
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We are so confident in our performance that we're offering a complete trial package to help you upgrade your workflow:
1. Request Your Free Trial: Receive a 10-assay kit plus an EasySort™ -5 Magnet (EC001), an $852 total value.
2. Share Your Insights: Submit a brief feedback report and receive a $50 voucher for your next order.
3. Keep the Gear: Purchase 500+ assays and the EasySort™ -5 Magnet is yours to keep.
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Start My Free Trial
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Citations of Elabscience Products
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| Product Name |
Neurobasal Medium
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Neurobasal-A Medium
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| Primary Application |
Short-term or long-term maintenance and cultivation of neuronal cells in pre-production and embryonic. |
Short-term or long-term maintenance and culture of both newly generated and mature neuronal cells. |
| Supplements |
Does not contain L-glutamine and requires the addition of B-27 neuron Supplement with vitamin A, 50×
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| Quality Control |
Sterilized by 0.1 μm filtration, Endotoxin Content < 3 EU/mL. |
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Cited Product
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