#version 2.4																																																																																																																																																																	
Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	MA:FImpact	MA:FIS	Amino_Acid_Change	MA:link.MSA	MA:link.PDB	MA:link.var	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	HGVSc	HGVSp	HGVSp_Short	Transcript_ID	Exon_Number	t_depth	t_ref_count	t_alt_count	n_depth	n_ref_count	n_alt_count	all_effects	Allele	Gene	Feature	Feature_type	Consequence	cDNA_position	CDS_position	Protein_position	Amino_acids	Codons	Existing_variation	ALLELE_NUM	DISTANCE	SYMBOL	SYMBOL_SOURCE	HGNC_ID	BIOTYPE	CANONICAL	CCDS	ENSP	SWISSPROT	TREMBL	UNIPARC	RefSeq	SIFT	PolyPhen	EXON	INTRON	DOMAINS	GMAF	AFR_MAF	AMR_MAF	ASN_MAF	EAS_MAF	EUR_MAF	SAS_MAF	AA_MAF	EA_MAF	CLIN_SIG	SOMATIC	PUBMED	MOTIF_NAME	MOTIF_POS	HIGH_INF_POS	MOTIF_SCORE_CHANGE	IMPACT	PICK	VARIANT_CLASS	TSL	HGVS_OFFSET	PHENO	chromosome_name_wu	start_wu	stop_wu	reference_wu	variant_wu	type_wu	gene_name_wu	transcript_name_wu	transcript_species_wu	transcript_source_wu	transcript_version_wu	strand_wu	transcript_status_wu	trv_type_wu	c_position_wu	amino_acid_change_wu	ucsc_cons_wu	domain_wu	all_domains_wu	deletion_substructures_wu	transcript_error_wu	default_gene_name_wu	gene_name_source_wu	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	evs_ea	evs_aa	evs_all	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	EVS_EA	EVS_AA	EVS_All
ABLIM1		genome.wustl.edu	GRCh37	10	116247760	116247760	-1	Missense_Mutation	SNP	T	T	C			sample1	normal1	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	medium	3.39	H333R	getma.org/?cm=msa&ty=f&p=ABLM1_HUMAN&rb=285&re=339&var=H333R	getma.org/pdb.php?prot=ABLM1_HUMAN&from=285&to=339&var=H333R	getma.org/?cm=var&var=hg19,10,116247760,T,C&fts=all	db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3	c.998A>G	p.His333Arg	p.H333R	ENST00000277895	8/23	0	1000	1010	0			ABLIM1,missense_variant,p.His273Arg,ENST00000533213,;ABLIM1,missense_variant,p.His273Arg,ENST00000369252,NM_001003408.1,NM_001003407.1;ABLIM1,missense_variant,p.His17Arg,ENST00000392952,NM_006720.3;ABLIM1,missense_variant,p.His17Arg,ENST00000369266,;ABLIM1,missense_variant,p.His333Arg,ENST00000277895,NM_002313.5;ABLIM1,missense_variant,p.His17Arg,ENST00000369253,;ABLIM1,missense_variant,p.His17Arg,ENST00000428430,;ABLIM1,upstream_gene_variant,,ENST00000440467,;ABLIM1,missense_variant,p.His273Arg,ENST00000392955,;ABLIM1,missense_variant,p.His273Arg,ENST00000369256,;	C	ENSG00000099204	ENST00000277895	Transcript	missense_variant	1096/2657	998/2337	333/778	H/R	cAt/cGt	COSM1474374,COSM1474373,COSM1474375	1		ABLIM1	HGNC	78	protein_coding	YES	CCDS7590.1	ENSP00000277895	ABLM1_HUMAN		UPI0000418D06	NM_002313.5	deleterious(0)	probably_damaging(0.988)	8/23		PROSITE_profiles:PS50023,hmmpanther:PTHR24213:SF18,hmmpanther:PTHR24213,Gene3D:2.10.110.10,SMART_domains:SM00132,Superfamily_domains:SSF57716											1,1,1						MODERATE	1	SNV			1,1,1	10	116247760	116247760	T	C	SNP	ABLIM1	ENST00000277895	human	ensembl	69_37n	-1	known	missense	c.998	p.H333R	1000	smart_Znf_LIM	pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM	-	no_errors	ABLIM1	HGNC	ENSG00000099204	77	0	0	36	13	26.53	-	-	-	10	116247760	116247760	T	C	SNP	ABLIM1	ENST00000277895	human	ensembl	69_37n	-1	known	missense	c.998	p.H333R	1000	smart_Znf_LIM	pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM	-	no_errors	ABLIM1	HGNC	-	-	-
ABLIM1		genome.wustl.edu	GRCh37	10	116247760	116247760	-1	Missense_Mutation	SNP	T	T	C			sample2	normal2	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	medium	3.39	H333R	getma.org/?cm=msa&ty=f&p=ABLM1_HUMAN&rb=285&re=339&var=H333R	getma.org/pdb.php?prot=ABLM1_HUMAN&from=285&to=339&var=H333R	getma.org/?cm=var&var=hg19,10,116247760,T,C&fts=all	db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3	c.998A>G	p.His333Arg	p.H333R	ENST00000277895	8/23	0	2000	2010	0			ABLIM1,missense_variant,p.His273Arg,ENST00000533213,;ABLIM1,missense_variant,p.His273Arg,ENST00000369252,NM_001003408.1,NM_001003407.1;ABLIM1,missense_variant,p.His17Arg,ENST00000392952,NM_006720.3;ABLIM1,missense_variant,p.His17Arg,ENST00000369266,;ABLIM1,missense_variant,p.His333Arg,ENST00000277895,NM_002313.5;ABLIM1,missense_variant,p.His17Arg,ENST00000369253,;ABLIM1,missense_variant,p.His17Arg,ENST00000428430,;ABLIM1,upstream_gene_variant,,ENST00000440467,;ABLIM1,missense_variant,p.His273Arg,ENST00000392955,;ABLIM1,missense_variant,p.His273Arg,ENST00000369256,;	C	ENSG00000099204	ENST00000277895	Transcript	missense_variant	1096/2657	998/2337	333/778	H/R	cAt/cGt	COSM1474374,COSM1474373,COSM1474375	1		ABLIM1	HGNC	78	protein_coding	YES	CCDS7590.1	ENSP00000277895	ABLM1_HUMAN		UPI0000418D06	NM_002313.5	deleterious(0)	probably_damaging(0.988)	8/23		PROSITE_profiles:PS50023,hmmpanther:PTHR24213:SF18,hmmpanther:PTHR24213,Gene3D:2.10.110.10,SMART_domains:SM00132,Superfamily_domains:SSF57716											1,1,1						MODERATE	1	SNV			1,1,1	10	116247760	116247760	T	C	SNP	ABLIM1	ENST00000277895	human	ensembl	69_37n	-1	known	missense	c.998	p.H333R	1000	smart_Znf_LIM	pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM	-	no_errors	ABLIM1	HGNC	ENSG00000099204	77	0	0	36	13	26.53	-	-	-	10	116247760	116247760	T	C	SNP	ABLIM1	ENST00000277895	human	ensembl	69_37n	-1	known	missense	c.998	p.H333R	1000	smart_Znf_LIM	pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM	-	no_errors	ABLIM1	HGNC	-	-	-
ABLIM1		genome.wustl.edu	GRCh37	10	116247760	116247760	-1	Missense_Mutation	SNP	T	T	C			sample3	normal3	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	medium	3.39	H333R	getma.org/?cm=msa&ty=f&p=ABLM1_HUMAN&rb=285&re=339&var=H333R	getma.org/pdb.php?prot=ABLM1_HUMAN&from=285&to=339&var=H333R	getma.org/?cm=var&var=hg19,10,116247760,T,C&fts=all	db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3	c.998A>G	p.His333Arg	p.H333R	ENST00000277895	8/23	0	3000	3010	0			ABLIM1,missense_variant,p.His273Arg,ENST00000533213,;ABLIM1,missense_variant,p.His273Arg,ENST00000369252,NM_001003408.1,NM_001003407.1;ABLIM1,missense_variant,p.His17Arg,ENST00000392952,NM_006720.3;ABLIM1,missense_variant,p.His17Arg,ENST00000369266,;ABLIM1,missense_variant,p.His333Arg,ENST00000277895,NM_002313.5;ABLIM1,missense_variant,p.His17Arg,ENST00000369253,;ABLIM1,missense_variant,p.His17Arg,ENST00000428430,;ABLIM1,upstream_gene_variant,,ENST00000440467,;ABLIM1,missense_variant,p.His273Arg,ENST00000392955,;ABLIM1,missense_variant,p.His273Arg,ENST00000369256,;	C	ENSG00000099204	ENST00000277895	Transcript	missense_variant	1096/2657	998/2337	333/778	H/R	cAt/cGt	COSM1474374,COSM1474373,COSM1474375	1		ABLIM1	HGNC	78	protein_coding	YES	CCDS7590.1	ENSP00000277895	ABLM1_HUMAN		UPI0000418D06	NM_002313.5	deleterious(0)	probably_damaging(0.988)	8/23		PROSITE_profiles:PS50023,hmmpanther:PTHR24213:SF18,hmmpanther:PTHR24213,Gene3D:2.10.110.10,SMART_domains:SM00132,Superfamily_domains:SSF57716											1,1,1						MODERATE	1	SNV			1,1,1	10	116247760	116247760	T	C	SNP	ABLIM1	ENST00000277895	human	ensembl	69_37n	-1	known	missense	c.998	p.H333R	1000	smart_Znf_LIM	pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM	-	no_errors	ABLIM1	HGNC	ENSG00000099204	77	0	0	36	13	26.53	-	-	-	10	116247760	116247760	T	C	SNP	ABLIM1	ENST00000277895	human	ensembl	69_37n	-1	known	missense	c.998	p.H333R	1000	smart_Znf_LIM	pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM	-	no_errors	ABLIM1	HGNC	-	-	-
CADM2		genome.wustl.edu	GRCh37	3	85932472	85932472	1	Missense_Mutation	SNP	C	C	T			sample2	normal2	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx							db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3			p.R81R	ENST00000407528	3/10	0	4000	4010	0			CADM2,synonymous_variant,p.=,ENST00000383699,NM_001167675.1,NM_001256504.1,NM_001256505.1;CADM2,synonymous_variant,,ENST00000407528,NM_001167674.1;CADM2,synonymous_variant,p.=,ENST00000405615,NM_153184.3;	T	ENSG00000175161	ENST00000407528	Transcript	synonymous_variant	305/1422	243/1308	81/435	R	cgC/cgT	COSM1178952,COSM1178953	1		CADM2	HGNC	29849	protein_coding		CCDS54614.1	ENSP00000384575	CADM2_HUMAN	G3XHN8_HUMAN	UPI000006DE82	NM_001167674.1			3/10		PROSITE_profiles:PS50835,hmmpanther:PTHR23277,hmmpanther:PTHR23277:SF56,Pfam_domain:PF07686,Gene3D:2.60.40.10,SMART_domains:SM00408,SMART_domains:SM00409,Superfamily_domains:SSF48726											1,1						LOW		SNV			1,1	3	85932472	85932472	C	T	SNP	CADM2	ENST00000405615	human	ensembl	69_37n	1	known	silent	c.249	p.R83	920	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_CD80_C2-set,pfam_Ig_V-set,pfam_Ig_C1-set,smart_Ig_sub,smart_Ig_sub2,smart_Neurexin-like,pfscan_Ig-like	-	no_errors	CADM2	HGNC	ENSG00000175161	57	0	0	22	23	51.11	-	-	-	3	85932472	85932472	C	T	SNP	CADM2	ENST00000405615	human	ensembl	69_37n	1	known	silent	c.249	p.R83	920	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_CD80_C2-set,pfam_Ig_V-set,pfam_Ig_C1-set,smart_Ig_sub,smart_Ig_sub2,smart_Neurexin-like,pfscan_Ig-like	-	no_errors	CADM2	HGNC	-	-	-
CADM2		genome.wustl.edu	GRCh37	3	85932472	85932472	1	Missense_Mutation	SNP	C	C	T			sample3	normal3	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx							db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3			p.R81R	ENST00000407528	3/10	0	5000	5010	0			CADM2,synonymous_variant,p.=,ENST00000383699,NM_001167675.1,NM_001256504.1,NM_001256505.1;CADM2,synonymous_variant,,ENST00000407528,NM_001167674.1;CADM2,synonymous_variant,p.=,ENST00000405615,NM_153184.3;	T	ENSG00000175161	ENST00000407528	Transcript	synonymous_variant	305/1422	243/1308	81/435	R	cgC/cgT	COSM1178952,COSM1178953	1		CADM2	HGNC	29849	protein_coding		CCDS54614.1	ENSP00000384575	CADM2_HUMAN	G3XHN8_HUMAN	UPI000006DE82	NM_001167674.1			3/10		PROSITE_profiles:PS50835,hmmpanther:PTHR23277,hmmpanther:PTHR23277:SF56,Pfam_domain:PF07686,Gene3D:2.60.40.10,SMART_domains:SM00408,SMART_domains:SM00409,Superfamily_domains:SSF48726											1,1						LOW		SNV			1,1	3	85932472	85932472	C	T	SNP	CADM2	ENST00000405615	human	ensembl	69_37n	1	known	silent	c.249	p.R83	920	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_CD80_C2-set,pfam_Ig_V-set,pfam_Ig_C1-set,smart_Ig_sub,smart_Ig_sub2,smart_Neurexin-like,pfscan_Ig-like	-	no_errors	CADM2	HGNC	ENSG00000175161	57	0	0	22	23	51.11	-	-	-	3	85932472	85932472	C	T	SNP	CADM2	ENST00000405615	human	ensembl	69_37n	1	known	silent	c.249	p.R83	920	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_CD80_C2-set,pfam_Ig_V-set,pfam_Ig_C1-set,smart_Ig_sub,smart_Ig_sub2,smart_Neurexin-like,pfscan_Ig-like	-	no_errors	CADM2	HGNC	-	-	-
ERBB2		genome.wustl.edu	GRCh37	12	43944926	43944926	-1	Missense_Mutation	SNP	T	T	C			sample4	normal4	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	medium	2.85	Y80C	getma.org/?cm=msa&ty=f&p=ATS20_HUMAN&rb=40&re=186&var=Y80C		getma.org/?cm=var&var=hg19,12,43944926,T,C&fts=all	db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3		p.Tyr80Cys	p.Y80C	ENST00000389420	2/39	0	6000	6010	0			ADAMTS20,missense_variant,p.Tyr80Cys,ENST00000389420,NM_025003.3;ADAMTS20,missense_variant,p.Tyr80Cys,ENST00000553158,;	C	ENSG00000173157	ENST00000389420	Transcript	missense_variant	239/6076	239/5733	80/1910	Y/C	tAt/tGt	COSM1476552,COSM1476551	1		ADAMTS20	HGNC	17178	protein_coding	YES	CCDS31778.2	ENSP00000374071	ATS20_HUMAN		UPI00004565F4	NM_025003.3	deleterious(0)	probably_damaging(1)	2/39		hmmpanther:PTHR13723,hmmpanther:PTHR13723:SF165,Pfam_domain:PF01562											1,1						MODERATE	1	SNV			1,1	12	43944926	43944926	T	C	SNP	ADAMTS20	ENST00000389420	human	ensembl	69_37n	-1	known	missense	c.239	p.Y80C	1000	pfam_Peptidase_M12B_N	pfam_Pept_M12B_GON-ADAMTSs,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_Peptidase_M12B,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS,pfscan_Pept_M12B_GON-ADAMTSs,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B	-	no_errors	ADAMTS20	HGNC	ENSG00000173157	50	0	0	19	17	45.95	-	-	-	12	43944926	43944926	T	C	SNP	ADAMTS20	ENST00000389420	human	ensembl	69_37n	-1	known	missense	c.239	p.Y80C	1000	pfam_Peptidase_M12B_N	pfam_Pept_M12B_GON-ADAMTSs,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_Peptidase_M12B,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS,pfscan_Pept_M12B_GON-ADAMTSs,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B	-	no_errors	ADAMTS20	HGNC	-	-	-
PIEZO1		genome.wustl.edu	GRCh37	16	88790292	88790292	-1	Missense_Mutation	SNP	T	T	C			sample3	normal5	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	low	1.18	Q1441R	getma.org/?cm=msa&ty=f&p=PIEZ1_HUMAN&rb=58&re=1627&var=Q1441R		getma.org/?cm=var&var=hg19,16,88790292,T,C&fts=all	db9d40fb-bfce-4c3b-a6c2-41c5c88982f1	a3254f8e-3bbd-42fc-abea-a5f25b7648b3	c.4322A>G	p.Gln1441Arg	p.Q1441R	ENST00000301015	31/51	0	7000	7010	0			PIEZO1,missense_variant,p.Gln1441Arg,ENST00000301015,NM_001142864.2;PIEZO1,missense_variant,p.Gln115Arg,ENST00000474606,;PIEZO1,upstream_gene_variant,,ENST00000327397,;PIEZO1,upstream_gene_variant,,ENST00000466823,;RP5-1142A6.9,downstream_gene_variant,,ENST00000564984,;PIEZO1,non_coding_transcript_exon_variant,,ENST00000566414,;PIEZO1,upstream_gene_variant,,ENST00000419505,;PIEZO1,upstream_gene_variant,,ENST00000497793,;PIEZO1,upstream_gene_variant,,ENST00000495568,;PIEZO1,downstream_gene_variant,,ENST00000475586,;PIEZO1,downstream_gene_variant,,ENST00000491917,;	C	ENSG00000103335	ENST00000301015	Transcript	missense_variant	4569/8072	4322/7566	1441/2521	Q/R	cAg/cGg	COSM1479166	1		PIEZO1	HGNC	28993	protein_coding	YES	CCDS54058.1	ENSP00000301015	PIEZ1_HUMAN		UPI0001B300F3	NM_001142864.2	tolerated(0.25)	possibly_damaging(0.78)	31/51		hmmpanther:PTHR13167,hmmpanther:PTHR13167:SF40											1						MODERATE	1	SNV			1	16	88790292	88790292	T	C	SNP	PIEZO1	ENST00000301015	human	ensembl	69_37n	-1	novel	missense	c.4322	p.Q1441R	1000		pfam_DUF3595	-	no_errors	PIEZO1	HGNC	ENSG00000103335	37	0	0	20	8	28.57	-	-	-	16	88790292	88790292	T	C	SNP	PIEZO1	ENST00000301015	human	ensembl	69_37n	-1	novel	missense	c.4322	p.Q1441R	1000		pfam_DUF3595	-	no_errors	PIEZO1	HGNC	-	-	-