# Versions: VERSIONS: roslin-core-2.1.2, roslin-variant-2.5.7, cmo-1.9.13 Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID HGVSc HGVSp Amino_Acid_Change Transcript_ID Exon_Number t_depth t_ref_count t_alt_count n_depth n_ref_count n_alt_count ASCN.TOTAL_COPY_NUMBER ASCN.MINOR_COPY_NUMBER ASCN.EXPECTED_ALT_COPIES ASCN.CCF_EXPECTED_COPIES ASCN.CCF_EXPECTED_COPIES_LOWER ASCN.CCF_EXPECTED_COPIES_UPPER ASCN.ASCN_INTEGER_COPY_NUMBER ASCN.ASCN_METHOD ASCN.CLONAL KMT2C 58508 mskcc.org GRCh37 7 152132724 152132724 + Nonsense_Mutation SNP T T A novel NA FAKE_P001_S2 FAKE_P001_N1 T T NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.148A>T p.Arg50Ter p.R50* ENST00000262189 1/59 1278 1015 263 1554 1547 0 2 1 1 0.541 0.506 0.577 0 FACETS CLONAL KMT2C 58508 mskcc.org GRCh37 7 152132724 152132724 + Nonsense_Mutation SNP T T A novel NA FAKE_P001_S3 FAKE_P001_N1 T T NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.148A>T p.Arg50Ter p.R50* ENST00000262189 1/59 1379 910 469 1554 1547 0 3 1 1 1 0.994 1 1 FACETS SUBCLONAL KMT2C 58508 mskcc.org GRCh37 7 152132724 152132724 + Nonsense_Mutation SNP T T A novel NA FAKE_P001_S4 FAKE_P001_N1 T T NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.148A>T p.Arg50Ter p.R50* ENST00000262189 1/59 217 197 20 1554 1547 0 2 1 NA NA NA 1 0 FACETS CLONAL KMT2C 58508 mskcc.org GRCh37 7 152132724 152132724 + Nonsense_Mutation SNP T T A novel NA FAKE_P001_S5 FAKE_P001_N1 T T NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.148A>T p.Arg50Ter p.R50* ENST00000262189 1/59 1421 759 662 1554 1547 0 2 1 1 1 0.986 1 0 FACETS CLONAL KMT2C 58508 mskcc.org GRCh37 7 152132724 152132724 + Nonsense_Mutation SNP T T A novel NA FAKE_P001_S6 FAKE_P001_N1 T T NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.148A>T p.Arg50Ter p.R50* ENST00000262189 1/59 1470 943 527 1554 1547 0 2 1 1 0.979 0.938 1 0 FACETS CLONAL TP53 7157 mskcc.org GRCh37 2 158617575 158617575 + Missense_Mutation SNP G G C novel NA FAKE_P001_S6 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.1081C>G p.His361Asp p.H361D ENST00000263640 9/11 539 394 145 666 664 2 3 1 1 1 0.921 1 1 FACETS SUBCLONAL PIK3C2G 5288 mskcc.org GRCh37 12 18658268 18658268 + Missense_Mutation SNP G G A novel NA FAKE_P001_S3 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.3073G>A p.Val1025Ile p.V1025I ENST00000266497 22/31 308 287 21 533 533 0 2 1 1 0.175 0.134 0.222 0 FACETS CLONAL TERT 7015 mskcc.org GRCh37 5 1295228 1295228 + 5'Flank SNP G G A novel NA FAKE_P001_S2 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA ENST00000310581 1450 926 524 2223 2214 1 2 1 1 0.95 0.911 0.99 0 FACETS CLONAL TERT 7015 mskcc.org GRCh37 5 1295228 1295228 + 5'Flank SNP G G A novel NA FAKE_P001_S3 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA ENST00000310581 1549 956 593 2238 2222 1 2 1 1 0.982 0.944 1 0 FACETS CLONAL TERT 7015 mskcc.org GRCh37 5 1295228 1295228 + 5'Flank SNP G G A novel NA FAKE_P001_S4 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA ENST00000310581 202 180 22 2232 2224 1 2 1 NA NA NA 1 0 FACETS CLONAL TERT 7015 mskcc.org GRCh37 5 1295228 1295228 + 5'Flank SNP G G A novel NA FAKE_P001_S5 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA ENST00000310581 1616 936 680 2221 2211 1 2 1 1 0.939 0.906 0.971 0 FACETS CLONAL TERT 7015 mskcc.org GRCh37 5 1295228 1295228 + 5'Flank SNP G G A novel NA FAKE_P001_S6 FAKE_P001_N1 G G NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA ENST00000310581 1499 964 535 2210 2201 1 2 1 1 0.975 0.935 1 0 FACETS CLONAL HIST1H1B 3009 mskcc.org GRCh37 6 27835010 27835011 + Frame_Shift_Ins INS - - G novel NA FAKE_P001_S3 FAKE_P001_N1 - - NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.297dupC p.Lys100GlnfsTer10 p.K100Qfs*10 ENST00000331442 1/1 29 15 14 57 57 0 2 1 1 1 0.878 1 0 FACETS CLONAL HIST1H1B 3009 mskcc.org GRCh37 6 27835010 27835011 + Frame_Shift_Ins INS - - G novel NA FAKE_P001_S6 FAKE_P001_N1 - - NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.297dupC p.Lys100GlnfsTer10 p.K100Qfs*10 ENST00000331442 1/1 32 18 14 57 57 0 2 1 1 1 0.862 1 0 FACETS CLONAL SETD2 29072 mskcc.org GRCh37 3 47125376 47125377 + Frame_Shift_Del DEL CT CT - novel NA FAKE_P001_S2 FAKE_P001_N1 CT CT NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.5893_5894delAG p.Ser1965GlnfsTer10 p.S1965Qfs*10 ENST00000409792 12/21 355 257 98 659 658 0 2 1 1 0.726 0.653 0.801 0 FACETS CLONAL SETD2 29072 mskcc.org GRCh37 3 47125376 47125377 + Frame_Shift_Del DEL CT CT - novel NA FAKE_P001_S3 FAKE_P001_N1 CT CT NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.5893_5894delAG p.Ser1965GlnfsTer10 p.S1965Qfs*10 ENST00000409792 12/21 363 226 137 659 658 0 2 1 1 0.968 0.892 1 0 FACETS CLONAL SETD2 29072 mskcc.org GRCh37 3 47125376 47125377 + Frame_Shift_Del DEL CT CT - novel NA FAKE_P001_S5 FAKE_P001_N1 CT CT NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.5893_5894delAG p.Ser1965GlnfsTer10 p.S1965Qfs*10 ENST00000409792 12/21 250 127 123 659 658 0 2 1 1 1 0.969 1 0 FACETS CLONAL SETD2 29072 mskcc.org GRCh37 3 47125376 47125377 + Frame_Shift_Del DEL CT CT - novel NA FAKE_P001_S6 FAKE_P001_N1 CT CT NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.5893_5894delAG p.Ser1965GlnfsTer10 p.S1965Qfs*10 ENST00000409792 12/21 379 238 141 659 658 0 2 1 1 1 0.935 1 0 FACETS CLONAL PIK3R1 5295 mskcc.org GRCh37 5 67591116 67591127 + In_Frame_Del DEL TTATCCAGCTGA TTATCCAGCTGA - novel NA FAKE_P001_S2 FAKE_P001_N1 TTATCCAGCTGA TTATCCAGCTGA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.1709_1720delTTATCCAGCTGA p.Leu570_Leu573del p.L570_L573del ENST00000274335 12/15 91 43 48 342 341 0 2 1 1 1 0.969 1 0 FACETS CLONAL PIK3R1 5295 mskcc.org GRCh37 5 67591116 67591127 + In_Frame_Del DEL TTATCCAGCTGA TTATCCAGCTGA - novel NA FAKE_P001_S3 FAKE_P001_N1 TTATCCAGCTGA TTATCCAGCTGA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.1709_1720delTTATCCAGCTGA p.Leu570_Leu573del p.L570_L573del ENST00000274335 12/15 98 38 60 342 341 0 1 0 1 0.958 0.866 1 -1 FACETS SUBCLONAL PIK3R1 5295 mskcc.org GRCh37 5 67591116 67591127 + In_Frame_Del DEL TTATCCAGCTGA - - novel NA FAKE_P001_S5 FAKE_P001_N1 TTATCCAGCTGA TTATCCAGCTGA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.1709_1720delTTATCCAGCTGA p.Leu570_Leu573del p.L570_L573del ENST00000274335 12/15 48 5 43 342 341 0 2 1 2 0.999 0.932 1 0 FACETS CLONAL PIK3R1 5295 mskcc.org GRCh37 5 67591116 67591127 + In_Frame_Del DEL TTATCCAGCTGA TTATCCAGCTGA - novel NA FAKE_P001_S6 FAKE_P001_N1 TTATCCAGCTGA TTATCCAGCTGA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.1709_1720delTTATCCAGCTGA p.Leu570_Leu573del p.L570_L573del ENST00000274335 12/15 98 31 67 342 341 0 2 1 2 0.933 0.855 1 0 FACETS CLONAL PIK3R1 5295 mskcc.org GRCh37 5 67569289 67569290 + Frame_Shift_Del DEL GT GT - novel NA FAKE_P001_S2 FAKE_P001_N1 GT GT NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA c.407_408delTG p.Val136GlyfsTer4 p.V136Gfs*4 ENST00000274335 2/15 171 153 18 508 506 0 2 1 1 0.277 0.209 0.355 0 FACETS CLONAL