Use the `disabled` attribute to disable the combobox.

```html
<div class="min-w-[200px] md:min-w-0 max-w-[400px]">
  <sd-combobox size="lg" label="Label" placeholder="Disabled" placement="bottom" value="" disabled>
    <sd-option value="option-1">Option 1</sd-option>
    <sd-option value="option-2">Option 2</sd-option>
    <sd-option value="option-3">Option 3</sd-option>
    <sd-option value="option-4">Option 4</sd-option>
    <sd-option value="option-5">Option 5</sd-option>
  </sd-combobox>
</div>
```