export type SequenceType = 'dna' | 'rna' | 'protein' | 'auto';
export interface SequenceStats {
    length: number;
    gcPercent?: number;
    molecularWeight?: number;
}
/** What `validateSequence` would strip or flag, so a field can report it instead. */
export interface SequenceProblems {
    /** Ambiguous `N` bases (DNA/RNA only; `N` is asparagine in protein). */
    ambiguousBases: number;
    /** Unique characters outside the alphabet, upper-cased, in order of appearance. Whitespace is ignored. */
    invalidCharacters: string[];
}
/** Detects, validates, cleans, and computes stats (GC%, MW) for DNA, RNA, and protein sequences. */
export declare function useSequenceUtils(): {
    detectSequenceType: (seq: string) => "dna" | "rna" | "protein";
    validateSequence: (seq: string, type: SequenceType) => string;
    findSequenceProblems: (seq: string, type: "dna" | "rna" | "protein") => SequenceProblems;
    reverseComplement: (seq: string, type: "dna" | "rna") => string;
    calculateStats: (seq: string, type: "dna" | "rna" | "protein") => SequenceStats;
    formatFasta: (seq: string, lineWidth?: number) => string;
};