{
  "rootNode": "gt",
  "nodes": {
    "gt": {
      "label": "Genotype",
      "description": "Genotype",
      "type": "CATEGORICAL",
      "field": "FORMAT/GENOTYPE/TYPE",
      "outcomeMap": {
        "HET": {
          "nextNode": "gq"
        },
        "HOM_REF": {
          "nextNode": "exit_u3"
        },
        "HOM_VAR": {
          "nextNode": "gq"
        },
        "MIXED": {
          "nextNode": "gq"
        },
        "NO_CALL": {
          "nextNode": "exit_u3"
        },
        "UNAVAILABLE": {
          "nextNode": "exit_u3"
        }
      },
      "outcomeMissing": {
        "nextNode": "gq"
      },
      "outcomeDefault": {
        "nextNode": "gq"
      }
    },
    "gq": {
      "type": "BOOL",
      "label": "Genotype quality",
      "description": "Genotype quality",
      "query": {
        "field": "FORMAT/GQ",
        "operator": ">=",
        "value": 20
      },
      "outcomeTrue": {
        "nextNode": "only_IP"
      },
      "outcomeFalse": {
        "nextNode": "exit_u3"
      },
      "outcomeMissing": {
        "nextNode": "only_IP"
      }
    },
    "only_IP": {
      "type": "BOOL",
      "label": "Only if AD IP",
      "description": "Only AD IP suitable for pedigree.",
      "query": {
        "field": "FORMAT/VI",
        "operator": "contains_none",
        "value": ["AR", "AD", "XLR", "XLD", "YL", "MT", "AR_C"]
      },
      "outcomeTrue": {
        "nextNode": "vid_IP"
      },
      "outcomeFalse": {
        "nextNode": "vim"
      },
      "outcomeMissing": {
        "nextNode": "vim"
      }
    },
    "vim": {
      "type": "BOOL",
      "label": "Inheritance match",
      "description": "Inheritance match",
      "query": {
        "field": "FORMAT/VIG",
        "operator": "contains",
        "value": "field:INFO/CSQ/Gene"
      },
      "outcomeTrue": {
        "nextNode": "exit_u1"
      },
      "outcomeFalse": {
        "nextNode": "vid"
      },
      "outcomeMissing": {
        "nextNode": "exit_u2"
      }
    },
    "vim_IP": {
      "type": "BOOL",
      "label": "Inheritance match (IP)",
      "description": "Inheritance match",
      "query": {
        "field": "FORMAT/VIG",
        "operator": "contains",
        "value": "field:INFO/CSQ/Gene"
      },
      "outcomeTrue": {
        "nextNode": "exit_u4"
      },
      "outcomeFalse": {
        "nextNode": "exit_u3"
      },
      "outcomeMissing": {
        "nextNode": "exit_u4"
      }
    },
    "vid": {
      "type": "BOOL",
      "label": "Inheritance denovo",
      "description": "Inheritance denovo",
      "query": {
        "field": "FORMAT/VID",
        "operator": "==",
        "value": 1
      },
      "outcomeTrue": {
        "nextNode": "exit_u1"
      },
      "outcomeFalse": {
        "nextNode": "exit_u3"
      },
      "outcomeMissing": {
        "nextNode": "exit_u2"
      }
    },
    "vid_IP": {
      "type": "BOOL",
      "label": "Inheritance denovo (IP)",
      "description": "Inheritance denovo",
      "query": {
        "field": "FORMAT/VID",
        "operator": "==",
        "value": 1
      },
      "outcomeTrue": {
        "nextNode": "exit_u1"
      },
      "outcomeFalse": {
        "nextNode": "vim_IP"
      },
      "outcomeMissing": {
        "nextNode": "exit_u2"
      }
    },
    "exit_u1": {
      "label": "Usable: probably",
      "description": "Usable: probably",
      "type": "LEAF",
      "class": "U1"
    },
    "exit_u2": {
      "label": "Usable: maybe",
      "description": "Usable: maybe",
      "type": "LEAF",
      "class": "U2"
    },
    "exit_u3": {
      "label": "Usable: probably not",
      "description": "Usable: probably not",
      "type": "LEAF",
      "class": "U3"
    },
    "exit_u4": {
      "label": "Usable: if IP",
      "description": "Usable: in case of incomplete penetrance",
      "type": "LEAF",
      "class": "U4"
    }
  }
}