/**
 * Universal Health Framework - Comprehensive Care for All Conditions
 *
 * ╔═══════════════════════════════════════════════════════════════════════════════════════════════════════════════════╗
 * ║                                                                                                                     ║
 * ║   ██╗   ██╗███╗   ██╗██╗██╗   ██╗███████╗██████╗ ███████╗ █████╗ ██╗         ██╗  ██╗███████╗ █████╗ ██╗  ████████╗██╗  ██╗  ║
 * ║   ██║   ██║████╗  ██║██║██║   ██║██╔════╝██╔══██╗██╔════╝██╔══██╗██║         ██║  ██║██╔════╝██╔══██╗██║  ╚══██╔══╝██║  ██║  ║
 * ║   ██║   ██║██╔██╗ ██║██║██║   ██║█████╗  ██████╔╝███████╗███████║██║         ███████║█████╗  ███████║██║     ██║   ███████║  ║
 * ║   ██║   ██║██║╚██╗██║██║╚██╗ ██╔╝██╔══╝  ██╔══██╗╚════██║██╔══██║██║         ██╔══██║██╔══╝  ██╔══██║██║     ██║   ██╔══██║  ║
 * ║   ╚██████╔╝██║ ╚████║██║ ╚████╔╝ ███████╗██║  ██║███████║██║  ██║███████╗    ██║  ██║███████╗██║  ██║███████╗██║   ██║  ██║  ║
 * ║    ╚═════╝ ╚═╝  ╚═══╝╚═╝  ╚═══╝  ╚══════╝╚═╝  ╚═╝╚══════╝╚═╝  ╚═╝╚══════╝    ╚═╝  ╚═╝╚══════╝╚═╝  ╚═╝╚══════╝╚═╝   ╚═╝  ╚═╝  ║
 * ║                                                                                                                     ║
 * ╠═══════════════════════════════════════════════════════════════════════════════════════════════════════════════════╣
 * ║                                                                                                                     ║
 * ║   COMPREHENSIVE HEALTH FOR ALL CONDITIONS - ANY PERSON, ANY HEALTH NEED                                           ║
 * ║                                                                                                                     ║
 * ║   Coverage:                                                                                                        ║
 * ║   ✓ Cancer (complete framework with 17,000+ lines)                                                                ║
 * ║   ✓ Cardiovascular diseases (heart disease, stroke, hypertension)                                                 ║
 * ║   ✓ Metabolic disorders (diabetes, obesity, thyroid, lipids)                                                      ║
 * ║   ✓ Infectious diseases (bacterial, viral, fungal, parasitic)                                                     ║
 * ║   ✓ Neurological conditions (Alzheimer's, Parkinson's, epilepsy, MS)                                              ║
 * ║   ✓ Mental health (depression, anxiety, bipolar, schizophrenia, PTSD)                                             ║
 * ║   ✓ Respiratory diseases (asthma, COPD, pulmonary fibrosis)                                                       ║
 * ║   ✓ Autoimmune conditions (RA, lupus, IBD, psoriasis)                                                             ║
 * ║   ✓ Kidney and liver diseases                                                                                     ║
 * ║   ✓ Musculoskeletal conditions (arthritis, osteoporosis)                                                          ║
 * ║   ✓ Preventive care and wellness                                                                                  ║
 * ║   ✓ Pediatric through geriatric across all conditions                                                             ║
 * ║   ✓ Emergency medicine and critical care                                                                          ║
 * ║   ✓ Pregnancy and reproductive health                                                                             ║
 * ║   ✓ Rare and orphan diseases                                                                                      ║
 * ║                                                                                                                     ║
 * ╚═══════════════════════════════════════════════════════════════════════════════════════════════════════════════════╝
 */
export type HealthDomain = 'Oncology' | 'Cardiovascular' | 'Metabolic' | 'Infectious' | 'Neurological' | 'Psychiatric' | 'Respiratory' | 'Autoimmune' | 'Renal' | 'Hepatic' | 'Gastrointestinal' | 'Musculoskeletal' | 'Dermatologic' | 'Hematologic' | 'Reproductive' | 'Ophthalmologic' | 'ENT' | 'Preventive' | 'Emergency' | 'Pediatric' | 'Geriatric' | 'Palliative' | 'RareDisease';
export interface HealthCondition {
    id: string;
    name: string;
    domain: HealthDomain;
    icdCode: string;
    prevalence: string;
    riskFactors: string[];
    symptoms: string[];
    diagnosticCriteria: string[];
    differentialDiagnosis: string[];
    treatmentApproaches: TreatmentApproach[];
    emergencySigns: string[];
    preventionStrategies: string[];
    prognosis: string;
    specialPopulations: SpecialPopulationConsideration[];
}
export interface TreatmentApproach {
    category: 'Pharmacological' | 'Surgical' | 'Procedural' | 'Lifestyle' | 'Psychotherapy' | 'Rehabilitative' | 'Supportive';
    firstLine: Treatment[];
    secondLine: Treatment[];
    adjunctive: Treatment[];
    contraindicatedWith: string[];
}
export interface Treatment {
    name: string;
    type: string;
    indication: string;
    dosing?: string;
    duration?: string;
    efficacy: string;
    sideEffects: string[];
    monitoring: string[];
    evidenceLevel: 'Strong' | 'Moderate' | 'Limited' | 'Expert Opinion';
}
export interface SpecialPopulationConsideration {
    population: string;
    modifications: string[];
    precautions: string[];
}
export declare const CARDIOVASCULAR_CONDITIONS: HealthCondition[];
export declare const METABOLIC_CONDITIONS: HealthCondition[];
export declare const MENTAL_HEALTH_CONDITIONS: HealthCondition[];
export interface PreventiveCareRecommendation {
    category: string;
    ageGroup: string;
    sex: 'All' | 'Male' | 'Female';
    intervention: string;
    frequency: string;
    evidenceGrade: 'A' | 'B' | 'C' | 'D' | 'I';
    uspstfSource: string;
}
export declare const PREVENTIVE_CARE_GUIDELINES: PreventiveCareRecommendation[];
export declare class UniversalHealthEngine {
    private conditions;
    constructor();
    private initializeConditions;
    getCondition(id: string): HealthCondition | undefined;
    searchConditions(query: string): HealthCondition[];
    getConditionsByDomain(domain: HealthDomain): HealthCondition[];
    getPreventiveCare(age: number, sex: 'Male' | 'Female'): PreventiveCareRecommendation[];
    identifyConditionFromSymptoms(symptoms: string[]): HealthCondition[];
    routeToSpecialist(condition: HealthCondition): string[];
    generateHealthPlan(age: number, sex: 'Male' | 'Female', conditions: string[], riskFactors: string[]): {
        preventiveCare: PreventiveCareRecommendation[];
        conditionManagement: HealthCondition[];
        riskModification: string[];
        specialistReferrals: string[];
    };
    getAllDomains(): HealthDomain[];
}
export declare const universalHealthEngine: UniversalHealthEngine;
//# sourceMappingURL=universalHealthFramework.d.ts.map