/**
 * Comprehensive Cancer Survivorship and Late Effects Management
 *
 * ╔═══════════════════════════════════════════════════════════════════════════════╗
 * ║  SURVIVORSHIP CARE - ENSURING CURE AND QUALITY OF LIFE                       ║
 * ╠═══════════════════════════════════════════════════════════════════════════════╣
 * ║  This module provides:                                                        ║
 * ║  - Surveillance protocols for recurrence detection                           ║
 * ║  - Late effects screening and management                                     ║
 * ║  - Secondary malignancy prevention                                           ║
 * ║  - Psychosocial support frameworks                                           ║
 * ║  - Fertility and family planning guidance                                    ║
 * ║  - Rehabilitation and quality of life optimization                           ║
 * ╚═══════════════════════════════════════════════════════════════════════════════╝
 */
export interface SurvivorshipCareplan {
    cancerType: string;
    stage: string;
    treatmentReceived: TreatmentSummary;
    surveillanceProtocol: SurveillanceProtocol;
    lateEffectsScreening: LateEffectsScreening[];
    secondaryMalignancyScreening: SecondaryMalignancyScreen[];
    psychosocialSupport: PsychosocialPlan;
    rehabilitationNeeds: RehabilitationPlan;
    healthMaintenanceRecommendations: HealthMaintenance[];
}
export interface TreatmentSummary {
    surgery: SurgicalSummary[];
    radiation: RadiationSummary[];
    systemicTherapy: SystemicTherapySummary[];
    transplant?: TransplantSummary;
    otherTreatments: string[];
}
export interface SurgicalSummary {
    procedure: string;
    date: string;
    findings: string;
    complications: string[];
    longTermConsiderations: string[];
}
export interface RadiationSummary {
    site: string;
    modality: 'EBRT' | 'IMRT' | 'SBRT' | 'Proton' | 'Brachytherapy' | 'TBI';
    totalDose: string;
    fractions: number;
    completionDate: string;
    acuteToxicities: string[];
    expectedLateEffects: string[];
}
export interface SystemicTherapySummary {
    agentClass: string;
    specificAgents: string[];
    cumulativeDoses?: Record<string, string>;
    duration: string;
    completionDate: string;
    significantToxicities: string[];
    expectedLateEffects: string[];
}
export interface TransplantSummary {
    type: 'Autologous' | 'Allogeneic';
    source: 'Bone Marrow' | 'PBSC' | 'Cord Blood';
    date: string;
    conditioning: string;
    gvhdHistory?: string;
    immuneReconstitution: string;
}
export interface SurveillanceProtocol {
    recurrenceRisk: 'Low' | 'Intermediate' | 'High';
    duration: string;
    visits: SurveillanceVisit[];
    discontinuationCriteria: string[];
}
export interface SurveillanceVisit {
    timing: string;
    components: SurveillanceComponent[];
    purpose: string;
}
export interface SurveillanceComponent {
    type: 'History/Physical' | 'Laboratory' | 'Imaging' | 'Endoscopy' | 'Biomarker';
    specific: string;
    frequency: string;
    rationale: string;
}
export interface LateEffectsScreening {
    system: OrganSystem;
    risks: LateEffectRisk[];
    screeningProtocol: ScreeningItem[];
    managementGuidance: ManagementGuideline[];
}
export type OrganSystem = 'Cardiovascular' | 'Pulmonary' | 'Endocrine' | 'Neurologic' | 'Musculoskeletal' | 'Renal' | 'Hepatic' | 'Auditory' | 'Ophthalmologic' | 'Dermatologic' | 'Reproductive' | 'Immunologic' | 'Gastrointestinal' | 'Cognitive';
export interface LateEffectRisk {
    effect: string;
    causingAgents: string[];
    riskLevel: 'Low' | 'Moderate' | 'High';
    typicalOnset: string;
    reversibility: 'Reversible' | 'Partially Reversible' | 'Irreversible' | 'Often Irreversible';
}
export interface ScreeningItem {
    test: string;
    startTiming: string;
    frequency: string;
    abnormalThreshold: string;
    action: string;
}
export interface ManagementGuideline {
    condition: string;
    interventions: string[];
    referralIndications: string[];
    preventiveMeasures: string[];
}
export interface SecondaryMalignancyScreen {
    malignancyType: string;
    riskFactors: string[];
    latencyPeriod: string;
    screeningRecommendation: string;
    frequency: string;
}
export interface PsychosocialPlan {
    riskFactors: string[];
    assessmentTools: string[];
    supportResources: SupportResource[];
    interventions: PsychosocialIntervention[];
}
export interface SupportResource {
    type: string;
    description: string;
    accessInstructions: string;
}
export interface PsychosocialIntervention {
    indication: string;
    intervention: string;
    expectedBenefit: string;
}
export interface RehabilitationPlan {
    physicalNeeds: RehabilitationNeed[];
    vocationalConsiderations: string[];
    adaptiveEquipment: string[];
    exerciseRecommendations: ExerciseRecommendation[];
}
export interface RehabilitationNeed {
    area: string;
    assessment: string;
    intervention: string;
    goals: string[];
}
export interface ExerciseRecommendation {
    type: 'Aerobic' | 'Resistance' | 'Flexibility' | 'Balance';
    frequency: string;
    intensity: string;
    duration: string;
    precautions: string[];
    benefits: string[];
}
export interface HealthMaintenance {
    category: string;
    recommendations: string[];
    frequency: string;
}
export declare const SURVEILLANCE_PROTOCOLS: Record<string, SurveillanceProtocol>;
export declare const LATE_EFFECTS_PROTOCOLS: LateEffectsScreening[];
export declare const SECONDARY_MALIGNANCY_SCREENING: SecondaryMalignancyScreen[];
export declare const PSYCHOSOCIAL_SUPPORT_FRAMEWORK: PsychosocialPlan;
export declare const EXERCISE_RECOMMENDATIONS: ExerciseRecommendation[];
export declare const HEALTH_MAINTENANCE_RECOMMENDATIONS: HealthMaintenance[];
export declare class SurvivorshipCareEngine {
    getSurveillanceProtocol(cancerType: string): SurveillanceProtocol | undefined;
    getLateEffectsScreening(treatments: string[]): LateEffectsScreening[];
    getSecondaryMalignancyScreening(treatmentHistory: {
        chemotherapy: string[];
        radiation: string[];
    }): SecondaryMalignancyScreen[];
    generateSurvivorshipCarePlan(cancerType: string, stage: string, treatmentSummary: TreatmentSummary): SurvivorshipCareplan;
    getExerciseRecommendations(): ExerciseRecommendation[];
    getHealthMaintenanceRecommendations(): HealthMaintenance[];
    getPsychosocialResources(): PsychosocialPlan;
}
export declare const survivorshipCareEngine: SurvivorshipCareEngine;
//# sourceMappingURL=survivorshipManagement.d.ts.map