/* tslint:disable */
/**
 * This file was automatically generated by json-schema-to-typescript.
 * DO NOT MODIFY IT BY HAND. Instead, modify the source JSONSchema file,
 * and run json-schema-to-typescript to regenerate this file.
 */

export type Sigcom = {
  /**
   * URI to schema or module for validation of this instance
   */
  $validator: string;
  [k: string]: any;
} & {
  /**
   * Age/ age group of the subjects
   */
  Age?: string;
  /**
   * ArrayExpress Accession code
   */
  ArrayExpress_Accession?: string;
  /**
   * The assay (TODO: validate against official list)
   */
  Assay: string;
  /**
   * The authors involved with the signature.
   */
  Authors?: string;
  /**
   * The batch
   */
  Batch?: string;
  /**
   * Region of the brain where the samples were harvested
   */
  Brain_Region?: string;
  /**
   * Category code of the gene set.
   */
  Category_Code?: string;
  /**
   * The cell line context
   */
  Cell_Line?: {
    /**
     * Ontology accession
     */
    Accession?: string;
    /**
     * Official name of cell line
     */
    Name: string;
    [k: string]: any;
  }[];
  /**
   * Subcellular localization information
   */
  Cellular_Compartment?: string;
  /**
   * Source platform
   */
  Chip?: string;
  /**
   * Location in the chromosome
   */
  Chromosome_Location?: string;
  /**
   * Protein complexes
   */
  Complex?: string;
  /**
   * Complex Identifier
   */
  Complex_ID?: string;
  /**
   * Names of the contributors
   */
  Contributor?: string;
  /**
   * Contributing organization
   */
  Contributor_Org?: string;
  /**
   * Description of the signature
   */
  Description?: string;
  /**
   * Tells whether the data are up regulated or down regulated
   */
  Direction?: "up" | "down";
  /**
   * Disease perturbations
   */
  Disease?: [
    {
      /**
       * The name of the disease
       */
      Name: string;
      /**
       * The ontology accession of the disease
       */
      Accession?: string;
      /**
       * External reference for the disease
       */
      Reference?: string;
      /**
       * Remark about this perturbation
       */
      Remarks?: string;
      [k: string]: any;
    }
  ];
  /**
   * Source of the Gene set
   */
  Exact_Source?: string;
  /**
   * The group being measured
   */
  Experimental_Group?: string;
  /**
   * External link for more details
   */
  External_Details_Url?: string;
  /**
   * GEO_Dataset_Accession code
   */
  geo_dataset?: string;
  /**
   * GEO_Platform_Accession code
   */
  platform?: string;
  /**
   * GEO_Series_Accession code
   */
  geo_id?: string;
  /**
   * Gene involved
   */
  Gene?: [
    {
      /**
       * The name of the gene
       */
      Name: string;
      /**
       * Human symbol of gene
       */
      Human_Symbol?: string;
      /**
       * Mouse symbol of gene
       */
      Mouse_Symbol?: string;
      /**
       * The ontology accession of the gene
       */
      Accession?: string;
      /**
       * The type of perturbation used
       */
      Gene_Perturbation?: string;
      /**
       * Remark about this perturbation
       */
      Remarks?: string;
      [k: string]: any;
    }
  ];
  /**
   * The family of genes (TODO: validate against official list)
   */
  Gene_Family?: string;
  /**
   * Name of the gene set
   */
  Gene_Set?: string;
  /**
   * Genome assembly build
   */
  Genome_Build?: string;
  /**
   * Gene ontology annotations
   */
  GO?: {
    /**
     * GO Biological Process.
     */
    Biological_Process?: string;
    /**
     * GO Cellular Component
     */
    Cellular_Component?: string;
    /**
     * Gene ontology ID
     */
    Accession: string;
    /**
     * GO molecular funtion
     */
    Molecular_Function?: string;
    [k: string]: any;
  };
  /**
   * Grant_Number code
   */
  Grant_Number?: string;
  /**
   * Enrichr Library
   */
  Library?: string;
  /**
   * The metabolite.
   */
  Metabolite?: {
    /**
     * HMDB ID
     */
    HMDID?: string;
    /**
     * Name of the metabolite
     */
    Name: string;
    [k: string]: any;
  };
  /**
   * The microRNA
   */
  MicroRNA?: string;
  /**
   * Mouse model
   */
  Mouse_Model?: string;
  /**
   * MGS_ID code
   */
  MGS_ID?: string;
  /**
   * NCI_PID_UUID code
   */
  NCI_PID_UUID?: string;
  /**
   * Number of genes in the signature
   */
  Number_of_genes: number;
  /**
   * The organism (TODO: validate against official list)
   */
  Organism: string;
  /**
   * The original string recognized during processing
   */
  Original_String: string;
  /**
   * Other perturbations
   */
  Other?: [
    {
      /**
       * The name of the perturbation
       */
      Name: string;
      /**
       * The ontology accession of the perturbation
       */
      Accession?: string;
      /**
       * Other metadata
       */
      Remarks?: string;
      [k: string]: any;
    }
  ];
  /**
   * PubMed ID
   */
  PMID?: string;
  /**
   * Post translational modification
   */
  PTM?: string;
  /**
   * Position Weight Matrices (PWMs)
   */
  PWM?: string;
  /**
   * The signature's pathway
   */
  Pathway?: {
    /**
     * External accession of the pathway (Wiki Pathway ID/Pathway ID/KEGG ID)
     */
    Accession?: string;
    /**
     * Name/ description of the pathway
     */
    Name: string;
    [k: string]: any;
  };
  /**
   * Patient Identifier
   */
  Patient_ID?: string;
  /**
   * The type of perturbation performed the study.
   */
  Perturbation_ID?: string;
  /**
   * The type of perturbation performed the study.
   */
  Perturbation_Type: string;
  /**
   * Phenotype perturbations
   */
  Phenotype?: [
    {
      /**
       * The name of the phenotype
       */
      Name: string;
      /**
       * External ID of the phenotype
       */
      Phenotype_ID?: string;
      [k: string]: any;
    }
  ];
  /**
   * The program/project involved witht the signature
   */
  Program?: string;
  /**
   * Structural protein domain.
   */
  Protein_Domain?: string;
  /**
   * The readout
   */
  Readout: string;
  /**
   * the sex of the sample
   */
  Sex?: "female" | "male" | "male v female" | "mixed sex";
  /**
   * Small Molecule used in the study
   */
  Small_Molecule?: [
    {
      /**
       * The name of the small molecule
       */
      Name: string;
      /**
       * The ontology accession of the small molecule
       */
      Accession?: string;
      /**
       * The concentration used for the study
       */
      Concentration?: string;
      /**
       * The Drug Bank ID accession of the small molecule
       */
      DrugBankID?: string;
      /**
       * The pubchem ID accession of the small molecule
       */
      PubChemID?: string;
      /**
       * Remark about this perturbation
       */
      Remarks?: string;
      /**
       * Remark about this perturbation
       */
      Smiles?: string;
      [k: string]: any;
    }
  ];
  /**
   * Sub-collection the signature belongs to
   */
  Sub_Category_Code?: "CGN" | "CM";
  /**
   * Alternative identifier
   */
  Systematic_Name?: string;
  /**
   * Figure/Table number from the published literature where the signature was extracted
   */
  Table_Number?: string;
  /**
   * The taxon involved in the study
   */
  Taxon?: string;
  /**
   * Time points used in the study.
   */
  Time_Point?: string;
  /**
   * The tissue context
   */
  Tissue?: {
    /**
     * Ontology accession
     */
    Accession?: string;
    /**
     * Name of the tissue
     */
    Name: string;
    [k: string]: any;
  }[];
  /**
   * Virus perturbations TODO: Merge with disease perturbations
   */
  Virus?: [
    {
      /**
       * The name of the disease
       */
      Name: string;
      /**
       * The ontology accession of the disease
       */
      Accession?: string;
      /**
       * External reference for the disease
       */
      Reference?: string;
      /**
       * Remark about this perturbation
       */
      Remarks?: string;
      [k: string]: any;
    }
  ];
  [k: string]: any;
};