Last updated: 2018-05-15

workflowr checks: (Click a bullet for more information)
  • R Markdown file: up-to-date

    Great! Since the R Markdown file has been committed to the Git repository, you know the exact version of the code that produced these results.

  • Environment: empty

    Great job! The global environment was empty. Objects defined in the global environment can affect the analysis in your R Markdown file in unknown ways. For reproduciblity it’s best to always run the code in an empty environment.

  • Seed: set.seed(12345)

    The command set.seed(12345) was run prior to running the code in the R Markdown file. Setting a seed ensures that any results that rely on randomness, e.g. subsampling or permutations, are reproducible.

  • Session information: recorded

    Great job! Recording the operating system, R version, and package versions is critical for reproducibility.

  • Repository version: 388e65e

    Great! You are using Git for version control. Tracking code development and connecting the code version to the results is critical for reproducibility. The version displayed above was the version of the Git repository at the time these results were generated.

    Note that you need to be careful to ensure that all relevant files for the analysis have been committed to Git prior to generating the results (you can use wflow_publish or wflow_git_commit). workflowr only checks the R Markdown file, but you know if there are other scripts or data files that it depends on. Below is the status of the Git repository when the results were generated:
    
    Ignored files:
        Ignored:    .DS_Store
        Ignored:    .Rhistory
        Ignored:    .Rproj.user/
        Ignored:    analysis/.DS_Store
        Ignored:    analysis/BH_robustness_cache/
        Ignored:    analysis/FDR_Null_cache/
        Ignored:    analysis/FDR_null_betahat_cache/
        Ignored:    analysis/Rmosek_cache/
        Ignored:    analysis/StepDown_cache/
        Ignored:    analysis/alternative2_cache/
        Ignored:    analysis/alternative_cache/
        Ignored:    analysis/ash_gd_cache/
        Ignored:    analysis/average_cor_gtex_2_cache/
        Ignored:    analysis/average_cor_gtex_cache/
        Ignored:    analysis/brca_cache/
        Ignored:    analysis/cash_deconv_cache/
        Ignored:    analysis/cash_fdr_1_cache/
        Ignored:    analysis/cash_fdr_2_cache/
        Ignored:    analysis/cash_fdr_3_cache/
        Ignored:    analysis/cash_fdr_4_cache/
        Ignored:    analysis/cash_fdr_5_cache/
        Ignored:    analysis/cash_fdr_6_cache/
        Ignored:    analysis/cash_plots_cache/
        Ignored:    analysis/cash_sim_1_cache/
        Ignored:    analysis/cash_sim_2_cache/
        Ignored:    analysis/cash_sim_3_cache/
        Ignored:    analysis/cash_sim_4_cache/
        Ignored:    analysis/cash_sim_5_cache/
        Ignored:    analysis/cash_sim_6_cache/
        Ignored:    analysis/cash_sim_7_cache/
        Ignored:    analysis/correlated_z_2_cache/
        Ignored:    analysis/correlated_z_3_cache/
        Ignored:    analysis/correlated_z_cache/
        Ignored:    analysis/create_null_cache/
        Ignored:    analysis/cutoff_null_cache/
        Ignored:    analysis/design_matrix_2_cache/
        Ignored:    analysis/design_matrix_cache/
        Ignored:    analysis/diagnostic_ash_cache/
        Ignored:    analysis/diagnostic_correlated_z_2_cache/
        Ignored:    analysis/diagnostic_correlated_z_3_cache/
        Ignored:    analysis/diagnostic_correlated_z_cache/
        Ignored:    analysis/diagnostic_plot_2_cache/
        Ignored:    analysis/diagnostic_plot_cache/
        Ignored:    analysis/efron_leukemia_cache/
        Ignored:    analysis/fitting_normal_cache/
        Ignored:    analysis/gaussian_derivatives_2_cache/
        Ignored:    analysis/gaussian_derivatives_3_cache/
        Ignored:    analysis/gaussian_derivatives_4_cache/
        Ignored:    analysis/gaussian_derivatives_5_cache/
        Ignored:    analysis/gaussian_derivatives_cache/
        Ignored:    analysis/gd-ash_cache/
        Ignored:    analysis/gd_delta_cache/
        Ignored:    analysis/gd_lik_2_cache/
        Ignored:    analysis/gd_lik_cache/
        Ignored:    analysis/gd_w_cache/
        Ignored:    analysis/knockoff_10_cache/
        Ignored:    analysis/knockoff_2_cache/
        Ignored:    analysis/knockoff_3_cache/
        Ignored:    analysis/knockoff_4_cache/
        Ignored:    analysis/knockoff_5_cache/
        Ignored:    analysis/knockoff_6_cache/
        Ignored:    analysis/knockoff_7_cache/
        Ignored:    analysis/knockoff_8_cache/
        Ignored:    analysis/knockoff_9_cache/
        Ignored:    analysis/knockoff_cache/
        Ignored:    analysis/knockoff_var_cache/
        Ignored:    analysis/marginal_z_alternative_cache/
        Ignored:    analysis/marginal_z_cache/
        Ignored:    analysis/mosek_reg_2_cache/
        Ignored:    analysis/mosek_reg_4_cache/
        Ignored:    analysis/mosek_reg_5_cache/
        Ignored:    analysis/mosek_reg_6_cache/
        Ignored:    analysis/mosek_reg_cache/
        Ignored:    analysis/pihat0_null_cache/
        Ignored:    analysis/plot_diagnostic_cache/
        Ignored:    analysis/poster_obayes17_cache/
        Ignored:    analysis/real_data_simulation_2_cache/
        Ignored:    analysis/real_data_simulation_3_cache/
        Ignored:    analysis/real_data_simulation_4_cache/
        Ignored:    analysis/real_data_simulation_5_cache/
        Ignored:    analysis/real_data_simulation_cache/
        Ignored:    analysis/rmosek_primal_dual_2_cache/
        Ignored:    analysis/rmosek_primal_dual_cache/
        Ignored:    analysis/seqgendiff_cache/
        Ignored:    analysis/simulated_correlated_null_2_cache/
        Ignored:    analysis/simulated_correlated_null_3_cache/
        Ignored:    analysis/simulated_correlated_null_cache/
        Ignored:    analysis/simulation_real_se_2_cache/
        Ignored:    analysis/simulation_real_se_cache/
        Ignored:    analysis/smemo_2_cache/
        Ignored:    data/LSI/
        Ignored:    docs/.DS_Store
        Ignored:    docs/figure/.DS_Store
        Ignored:    output/fig/
    
    
    Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.
Expand here to see past versions:
    File Version Author Date Message
    html 69e0c7d LSun 2018-05-14 Update to 1.0
    html e05bc83 LSun 2018-05-12 Update to 1.0
    rmd cc0ab83 Lei Sun 2018-05-11 update
    html 0f36d99 LSun 2017-12-21 Build site.
    html 7e06347 LSun 2017-11-11 Build site.
    html 2c74856 LSun 2017-11-11 Build site.
    rmd 60487d0 LSun 2017-11-11 wflow_publish(“analysis/seqgendiff.rmd”)

Introduction

In order to perform a large-scale simulation, we explore the seqgendiff::poisthin function developed by David.

library(seqgendiff)
source("../code/count_to_summary.R")
source("../code/gdash_lik.R")
counts <- readRDS("../data/liver.sim.rds")

More flexible effects

Instead of \(g = \pi_0\delta_0 + (1 - \pi_0)N(0, \sigma^2)\), we would like to add effects following \(g = \pi_0\delta_0 + \pi_1N(0, \sigma_1^2) + \pi_2N(0, \sigma_2^2)\).

The data is simulated by Poisson thinning, not by normal mean models.

Expand here to see past versions of plot_pihat0-1.png:
Version Author Date
0f36d99 LSun 2017-12-21
2c74856 LSun 2017-11-11

Expand here to see past versions of plot_mse-1.png:
Version Author Date
0f36d99 LSun 2017-12-21
2c74856 LSun 2017-11-11

Expand here to see past versions of plot_auc-1.png:
Version Author Date
0f36d99 LSun 2017-12-21
2c74856 LSun 2017-11-11

Expand here to see past versions of qvalue calibration plotting-1.png:
Version Author Date
0f36d99 LSun 2017-12-21
2c74856 LSun 2017-11-11

Expand here to see past versions of qvalue calibration plotting-2.png:
Version Author Date
0f36d99 LSun 2017-12-21
2c74856 LSun 2017-11-11

Session information

sessionInfo()
R version 3.4.3 (2017-11-30)
Platform: x86_64-apple-darwin15.6.0 (64-bit)
Running under: macOS High Sierra 10.13.4

Matrix products: default
BLAS: /Library/Frameworks/R.framework/Versions/3.4/Resources/lib/libRblas.0.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/3.4/Resources/lib/libRlapack.dylib

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] ashr_2.2-2        Rmosek_8.0.69     PolynomF_1.0-1   
 [4] CVXR_0.95         REBayes_1.2       Matrix_1.2-12    
 [7] SQUAREM_2017.10-1 EQL_1.0-0         ttutils_1.0-1    
[10] seqgendiff_0.1.0 

loaded via a namespace (and not attached):
 [1] gmp_0.5-13.1      Rcpp_0.12.16      compiler_3.4.3   
 [4] git2r_0.21.0      workflowr_1.0.1   R.methodsS3_1.7.1
 [7] R.utils_2.6.0     iterators_1.0.9   tools_3.4.3      
[10] digest_0.6.15     bit_1.1-12        evaluate_0.10.1  
[13] lattice_0.20-35   foreach_1.4.4     parallel_3.4.3   
[16] yaml_2.1.18       Rmpfr_0.6-1       ECOSolveR_0.4    
[19] stringr_1.3.0     knitr_1.20        rprojroot_1.3-2  
[22] bit64_0.9-7       grid_3.4.3        R6_2.2.2         
[25] rmarkdown_1.9     magrittr_1.5      whisker_0.3-2    
[28] MASS_7.3-47       codetools_0.2-15  backports_1.1.2  
[31] htmltools_0.3.6   scs_1.1-1         stringi_1.1.6    
[34] pscl_1.5.2        doParallel_1.0.11 truncnorm_1.0-7  
[37] R.oo_1.21.0      

This reproducible R Markdown analysis was created with workflowr 1.0.1