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} </style> <div class="fluid-row" id="header"> <h1 class="title toc-ignore">Regularized Gaussian Derivatives: Correlated Null N(0, 1) Z Scores</h1> <h4 class="author"><em>Lei Sun</em></h4> <h4 class="date"><em>2017-05-09</em></h4> </div> <p><strong>Last updated:</strong> 2018-05-15</p> <strong>workflowr checks:</strong> <small>(Click a bullet for more information)</small> <ul> <li> <details> <p><summary> <strong style="color:blue;">✔</strong> <strong>R Markdown file:</strong> up-to-date </summary></p> <p>Great! 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Below is the status of the Git repository when the results were generated: <pre><code> Ignored files: Ignored: .DS_Store Ignored: .Rhistory Ignored: .Rproj.user/ Ignored: analysis/.DS_Store Ignored: analysis/BH_robustness_cache/ Ignored: analysis/FDR_Null_cache/ Ignored: analysis/FDR_null_betahat_cache/ Ignored: analysis/Rmosek_cache/ Ignored: analysis/StepDown_cache/ Ignored: analysis/alternative2_cache/ Ignored: analysis/alternative_cache/ Ignored: analysis/ash_gd_cache/ Ignored: analysis/average_cor_gtex_2_cache/ Ignored: analysis/average_cor_gtex_cache/ Ignored: analysis/brca_cache/ Ignored: analysis/cash_deconv_cache/ Ignored: analysis/cash_fdr_1_cache/ Ignored: analysis/cash_fdr_2_cache/ Ignored: analysis/cash_fdr_3_cache/ Ignored: analysis/cash_fdr_4_cache/ Ignored: analysis/cash_fdr_5_cache/ Ignored: analysis/cash_fdr_6_cache/ Ignored: analysis/cash_plots_cache/ Ignored: analysis/cash_sim_1_cache/ Ignored: analysis/cash_sim_2_cache/ Ignored: analysis/cash_sim_3_cache/ Ignored: analysis/cash_sim_4_cache/ Ignored: analysis/cash_sim_5_cache/ Ignored: analysis/cash_sim_6_cache/ Ignored: analysis/cash_sim_7_cache/ Ignored: analysis/correlated_z_2_cache/ Ignored: analysis/correlated_z_3_cache/ Ignored: analysis/correlated_z_cache/ Ignored: analysis/create_null_cache/ Ignored: analysis/cutoff_null_cache/ Ignored: analysis/design_matrix_2_cache/ Ignored: analysis/design_matrix_cache/ Ignored: analysis/diagnostic_ash_cache/ Ignored: analysis/diagnostic_correlated_z_2_cache/ Ignored: analysis/diagnostic_correlated_z_3_cache/ Ignored: analysis/diagnostic_correlated_z_cache/ Ignored: analysis/diagnostic_plot_2_cache/ Ignored: analysis/diagnostic_plot_cache/ Ignored: analysis/efron_leukemia_cache/ Ignored: analysis/fitting_normal_cache/ Ignored: analysis/gaussian_derivatives_2_cache/ Ignored: analysis/gaussian_derivatives_3_cache/ Ignored: analysis/gaussian_derivatives_4_cache/ Ignored: analysis/gaussian_derivatives_5_cache/ Ignored: analysis/gaussian_derivatives_cache/ Ignored: analysis/gd-ash_cache/ Ignored: analysis/gd_delta_cache/ Ignored: analysis/gd_lik_2_cache/ Ignored: analysis/gd_lik_cache/ Ignored: analysis/gd_w_cache/ Ignored: analysis/knockoff_10_cache/ Ignored: analysis/knockoff_2_cache/ Ignored: analysis/knockoff_3_cache/ Ignored: analysis/knockoff_4_cache/ Ignored: analysis/knockoff_5_cache/ Ignored: analysis/knockoff_6_cache/ Ignored: analysis/knockoff_7_cache/ Ignored: analysis/knockoff_8_cache/ Ignored: analysis/knockoff_9_cache/ Ignored: analysis/knockoff_cache/ Ignored: analysis/knockoff_var_cache/ Ignored: analysis/marginal_z_alternative_cache/ Ignored: analysis/marginal_z_cache/ Ignored: analysis/mosek_reg_2_cache/ Ignored: analysis/mosek_reg_4_cache/ Ignored: analysis/mosek_reg_5_cache/ Ignored: analysis/mosek_reg_6_cache/ Ignored: analysis/mosek_reg_cache/ Ignored: analysis/pihat0_null_cache/ Ignored: analysis/plot_diagnostic_cache/ Ignored: analysis/poster_obayes17_cache/ Ignored: analysis/real_data_simulation_2_cache/ Ignored: analysis/real_data_simulation_3_cache/ Ignored: analysis/real_data_simulation_4_cache/ Ignored: analysis/real_data_simulation_5_cache/ Ignored: analysis/real_data_simulation_cache/ Ignored: analysis/rmosek_primal_dual_2_cache/ Ignored: analysis/rmosek_primal_dual_cache/ Ignored: analysis/seqgendiff_cache/ Ignored: analysis/simulated_correlated_null_2_cache/ Ignored: analysis/simulated_correlated_null_3_cache/ Ignored: analysis/simulated_correlated_null_cache/ Ignored: analysis/simulation_real_se_2_cache/ Ignored: analysis/simulation_real_se_cache/ Ignored: analysis/smemo_2_cache/ Ignored: data/LSI/ Ignored: docs/.DS_Store Ignored: docs/figure/.DS_Store Ignored: output/fig/ </code></pre> Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes. </details> </li> </ul> <details> <summary> <small><strong>Expand here to see past versions:</strong></small> </summary> <ul> <table style="border-collapse:separate; border-spacing:5px;"> <thead> <tr> <th style="text-align:left;"> File </th> <th style="text-align:left;"> Version </th> <th style="text-align:left;"> Author </th> <th style="text-align:left;"> Date </th> <th style="text-align:left;"> Message </th> </tr> </thead> <tbody> <tr> <td style="text-align:left;"> html </td> <td style="text-align:left;"> <a href="https://cdn.rawgit.com/LSun/truncash/e05bc836b3c74dc6ebca415afb5938675d6c5436/docs/mosek_reg_4.html" target="_blank">e05bc83</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2018-05-12 </td> <td style="text-align:left;"> Update to 1.0 </td> </tr> <tr> <td style="text-align:left;"> rmd </td> <td style="text-align:left;"> <a href="https://github.com/LSun/truncash/blob/cc0ab8379469bc3726f1508cd81e4ecd6fef1b1a/analysis/mosek_reg_4.rmd" target="_blank">cc0ab83</a> </td> <td style="text-align:left;"> Lei Sun </td> <td style="text-align:left;"> 2018-05-11 </td> <td style="text-align:left;"> update </td> </tr> <tr> <td style="text-align:left;"> html </td> <td style="text-align:left;"> <a href="https://cdn.rawgit.com/LSun/truncash/0f36d998db26444c5dd01502ea1af7fbd1129b22/docs/mosek_reg_4.html" target="_blank">0f36d99</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-12-21 </td> <td style="text-align:left;"> Build site. </td> </tr> <tr> <td style="text-align:left;"> html </td> <td style="text-align:left;"> <a href="https://cdn.rawgit.com/LSun/truncash/853a484bfacf347e109f6c8fb3ffaab5f4d6cc02/docs/mosek_reg_4.html" target="_blank">853a484</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-11-07 </td> <td style="text-align:left;"> Build site. </td> </tr> <tr> <td style="text-align:left;"> html </td> <td style="text-align:left;"> <a href="https://cdn.rawgit.com/LSun/truncash/4f032ada03363cc112612f17b5856e75c479feb8/docs/mosek_reg_4.html" target="_blank">4f032ad</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-11-05 </td> <td style="text-align:left;"> transfer </td> </tr> <tr> <td style="text-align:left;"> html </td> <td style="text-align:left;"> <a href="https://cdn.rawgit.com/LSun/truncash/a3fd9a30049e1de81e2004887021f4a4f2a179e3/docs/mosek_reg_4.html" target="_blank">a3fd9a3</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-05-16 </td> <td style="text-align:left;"> correlated null </td> </tr> <tr> <td style="text-align:left;"> rmd </td> <td style="text-align:left;"> <a href="https://github.com/LSun/truncash/blob/2ea685c0198df0b399401377b368b05224a19dca/analysis/mosek_reg_4.rmd" target="_blank">2ea685c</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-05-16 </td> <td style="text-align:left;"> null only </td> </tr> <tr> <td style="text-align:left;"> html </td> <td style="text-align:left;"> <a href="https://cdn.rawgit.com/LSun/truncash/603b826484567c644686dac0daf5b02b31c0d66a/docs/mosek_reg_4.html" target="_blank">603b826</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-05-11 </td> <td style="text-align:left;"> writeups </td> </tr> <tr> <td style="text-align:left;"> rmd </td> <td style="text-align:left;"> <a href="https://github.com/LSun/truncash/blob/11bfb0ff13bb877a5d6f416bde07bc6e5e967947/analysis/mosek_reg_4.rmd" target="_blank">11bfb0f</a> </td> <td style="text-align:left;"> LSun </td> <td style="text-align:left;"> 2017-05-11 </td> <td style="text-align:left;"> regularization on null </td> </tr> </tbody> </table> </ul> </details> <hr /> <div id="introduction" class="section level2"> <h2>Introduction</h2> <p>We are using a regularization term on <span class="math inline">\(w\)</span> which is</p> <p><span class="math display">\[ \sum\limits_{l = 1}^L\lambda_l\left|w_l\right| \ , \]</span> where</p> <p><span class="math display">\[ \lambda_l = \begin{cases} 0 & l \text{ is odd;} \\ \lambda / \rho^{l/2}, \ \ \ \ \lambda >0, \ \rho\in\left(0, 1\right) & l \text{ is even.} \end{cases} \]</span></p> <p>This regularization is meant to tackle multiple issues at once, including to restrict the number of Gaussian derivatives, to prevent overfitting, to stop the algorithm going crazy and unstable, and to generate non-negative empirical densities of the correlated null.</p> <p>We are not regularizing the odd order coefficients <a href="mosek_reg_3.html#regularizing_even_orders_only">because</a> they are generally small but non-negligible. Furthermore, unlike the even order ones, we don’t have a clear idea how <span class="math inline">\(\text{var}\left(W_l^s\right) = \bar{\rho_{ij}^l}\)</span> roughly decays with respect to <span class="math inline">\(l\)</span>.</p> <p>There are three tuning parameters in this regularization scheme, <span class="math inline">\(L\)</span>, the highest order of Gaussian derivative to fit, <span class="math inline">\(\lambda\)</span>, a general (global) regularization parameter, and <span class="math inline">\(\rho\)</span>, a specific (local) shrinkage parameter to control the decaying rate of <span class="math inline">\(w_l\)</span>. We are setting <span class="math inline">\(L = 10\)</span> and <span class="math inline">\(\rho = 0.5\)</span>, and try different choices of <span class="math inline">\(\lambda\)</span>.</p> <pre class="r"><code>L = 10 rho = 0.5</code></pre> <p>We are using four different kinds of data sets of correlated nulls simulated from the real GTEx/Liver data. The first, called “typical,” are <a href="gaussian_derivatives_2.html">data sets well studied and documented</a> for being fitted by Gaussian derivatives. The second, called “hostile,” are data sets that are very unfriendly to both <code>BH</code>’s FDR-controlling procedure and <code>ASH</code> in terms of its estimated <span class="math inline">\(\hat\pi_0\)</span>. The third, called “friendly,” on the contrary, are data sets that are very friendly to both <code>BH</code> and <code>ASH</code>, whose empirical distributions are yet not necessarily close to <span class="math inline">\(N\left(0, 1\right)\)</span>. Finally, the fourth, called “iid,” are independent random <span class="math inline">\(N\left(0, 1\right)\)</span> samples.</p> <p>The hope is for all four data sets, this regularization scheme could automatically reach a variety of goals and give a sufficiently good fit.</p> </div> <div id="typical" class="section level2"> <h2>Typical</h2> <p>The results of these data sets can be compared with previous documentation with known optimal Gaussian derivative orders, such as <a href="gaussian_derivatives_2.html">here</a>, <a href="mosek_reg.html#correlated_null7">here</a>, and <a href="mosek_reg_2.html#correlated_null">here</a>.</p> <div id="no-regularization-lambda-0" class="section level3"> <h3>No regularization: <span class="math inline">\(\lambda = 0\)</span></h3> <pre class="r"><code>CorNullPlot("typical", L, lambda = 0, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 3 pihat0 estimated by ASH: 0.184423 Unnormalized w: 0 : 1 ; 1 : -0.0358645746922219 ; 2 : 0.196863594846729 ; 3 : 0.00997486072754378 ; 4 : -0.0244265081565814 ; 5 : 0.000298521020828936 ; 6 : -0.00289686959704202 ; 7 : 0.000227258831584183 ; 8 : -0.000684282416825896 ; 9 : -8.21789726780818e-06 ; 10 : -3.3953875566361e-05 ; Normalized w: 0 : 1 ; 1 : -0.0358645746922219 ; 2 : 0.278407165769766 ; 3 : 0.0244333190378092 ; 4 : -0.119664962363111 ; 5 : 0.00327013393994956 ; 6 : -0.0777311680912606 ; 7 : 0.0161337765487923 ; 8 : -0.137402818804405 ; 9 : -0.00495042202521986 ; 10 : -0.064680127772705 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-6-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 489 Number of False Discoveries by ASH at lfsr = 0.05: 1446 pihat0 estimated by ASH: 0.1522796 Unnormalized w: 0 : 1 ; 1 : 0.0345501445384415 ; 2 : 0.733251674198138 ; 3 : -0.151188207900136 ; 4 : 0.185424312479517 ; 5 : -0.0533305072968751 ; 6 : 0.0211293095698867 ; 7 : -0.00647923650278792 ; 8 : 0.000823585128891623 ; 9 : -0.00028582227222612 ; 10 : -2.52784009252051e-05 ; Normalized w: 0 : 1 ; 1 : 0.0345501445384415 ; 2 : 1.03697446228378 ; 3 : -0.370333964481153 ; 4 : 0.908389902962399 ; 5 : -0.584206436993847 ; 6 : 0.566958870190842 ; 7 : -0.459980161008776 ; 8 : 0.165374581389968 ; 9 : -0.172177970302609 ; 10 : -0.0481538609204241 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-6-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0227244539615043 ; 2 : 0.92101434792072 ; 3 : 0.0222103145256307 ; 4 : 0.175694879344268 ; 5 : -0.0134165085467778 ; 6 : 0.00392982154182872 ; 7 : -0.00480255115990118 ; 8 : -0.000586133715906366 ; 9 : -0.000291508028046953 ; 10 : 2.65975448800262e-06 ; Normalized w: 0 : 1 ; 1 : 0.0227244539615043 ; 2 : 1.30251098196969 ; 3 : 0.0544039376145207 ; 4 : 0.860725609626624 ; 5 : -0.146970487480621 ; 6 : 0.105448177283665 ; 7 : -0.340947309892716 ; 8 : -0.117694716072657 ; 9 : -0.175603042426075 ; 10 : 0.00506667522509486 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-6-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9998824 Unnormalized w: 0 : 1 ; 1 : 948001617.513726 ; 2 : -1852913923.39639 ; 3 : 2388146729.0879 ; 4 : -1942466863.08905 ; 5 : 1219931877.00972 ; 6 : -554762623.066314 ; 7 : 190275605.485957 ; 8 : -51698609.2012088 ; 9 : 8514828.56300786 ; 10 : -1308353.32230037 ; Normalized w: 0 : 1 ; 1 : 948001617.513726 ; 2 : -2620416000.37712 ; 3 : 5849740917.16201 ; 4 : -9516105313.66569 ; 5 : 13363684153.1569 ; 6 : -14885843238.6285 ; 7 : 13508227953.9901 ; 8 : -10380998339.054 ; 9 : 5129292017.85067 ; 10 : -2492335812.82459 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-6-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 357 pihat0 estimated by ASH: 0.07619716 Unnormalized w: 0 : 1 ; 1 : 0.00386042091758454 ; 2 : 0.395233653180317 ; 3 : -0.0177592602991958 ; 4 : 0.0191478560140696 ; 5 : -0.00364437632299771 ; 6 : -0.00288104662639495 ; 7 : -0.000337256191165567 ; 8 : -0.000212164374593046 ; 9 : -4.66643453550456e-05 ; 10 : 1.37192624335069e-06 ; Normalized w: 0 : 1 ; 1 : 0.00386042091758454 ; 2 : 0.558944792633868 ; 3 : -0.0435011259422965 ; 4 : 0.0938049538055052 ; 5 : -0.0399221424028716 ; 6 : -0.0773065932355867 ; 7 : -0.0239428144113575 ; 8 : -0.0426022683063849 ; 9 : -0.0281103785445223 ; 10 : 0.00261343847306088 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-6-5.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-1" class="section level3"> <h3><span class="math inline">\(\lambda = 1\)</span></h3> <pre class="r"><code>CorNullPlot("typical", L, lambda = 1, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 3 pihat0 estimated by ASH: 0.184423 Unnormalized w: 0 : 1 ; 1 : -0.0360764946561849 ; 2 : 0.198386768132035 ; 3 : 0.00901395541835672 ; 4 : -0.0201370500252101 ; 5 : -0.000550122547300102 ; 6 : -0.000243659125003317 ; 7 : -1.92186474132937e-05 ; 8 : -0.000125953061368301 ; 9 : -2.93811804138163e-05 ; 10 : 1.51034667667792e-10 ; Normalized w: 0 : 1 ; 1 : -0.0360764946561849 ; 2 : 0.28056125808769 ; 3 : 0.0220795913391696 ; 4 : -0.0986509949733276 ; 5 : -0.00602629057096938 ; 6 : -0.00653806040214643 ; 7 : -0.00136438861704368 ; 8 : -0.0252911739999481 ; 9 : -0.0176990826129307 ; 10 : 2.87712122398752e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-7-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 489 Number of False Discoveries by ASH at lfsr = 0.05: 1446 pihat0 estimated by ASH: 0.1522796 Unnormalized w: 0 : 1 ; 1 : 0.0382720564222799 ; 2 : 0.723957047593695 ; 3 : -0.141261297887049 ; 4 : 0.17378916477765 ; 5 : -0.0472968968741243 ; 6 : 0.0173650746067691 ; 7 : -0.00532305271510779 ; 8 : 0.000511710551126635 ; 9 : -0.000219072768393111 ; 10 : -2.31826988482601e-05 ; Normalized w: 0 : 1 ; 1 : 0.0382720564222799 ; 2 : 1.02382987528259 ; 3 : -0.346018100226566 ; 4 : 0.851389553059418 ; 5 : -0.518111546359069 ; 6 : 0.465953847061092 ; 7 : -0.377899254626673 ; 8 : 0.10275066318801 ; 9 : -0.131968388316005 ; 10 : -0.0441616722276958 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-7-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0223556913438548 ; 2 : 0.916740955025879 ; 3 : 0.0218891094396244 ; 4 : 0.172881230445589 ; 5 : -0.0134617737282905 ; 6 : 0.00376825719933721 ; 7 : -0.00480328049020991 ; 8 : -0.000564405807267297 ; 9 : -0.000291745094113606 ; 10 : 8.09167312092846e-10 ; Normalized w: 0 : 1 ; 1 : 0.0223556913438548 ; 2 : 1.29646749178046 ; 3 : 0.0536171490510185 ; 4 : 0.846941601392408 ; 5 : -0.147466342700302 ; 6 : 0.101112951053052 ; 7 : -0.340999087208252 ; 8 : -0.113331786644218 ; 9 : -0.175745849891238 ; 10 : 1.54141594332499e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-7-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9998824 Unnormalized w: 0 : 1 ; 1 : 18.0701102380429 ; 2 : -36.0134906763067 ; 3 : 45.1561454250037 ; 4 : -37.2608396643896 ; 5 : 23.0978908836177 ; 6 : -10.5550014881213 ; 7 : 3.62691359800924 ; 8 : -0.968975075928181 ; 9 : 0.164546200480334 ; 10 : -0.0232098025643446 ; Normalized w: 0 : 1 ; 1 : 18.0701102380429 ; 2 : -50.9307669428299 ; 3 : 110.609515042172 ; 4 : -182.540089130822 ; 5 : 253.024717355007 ; 6 : -283.220409960608 ; 7 : 257.485322546778 ; 8 : -194.568651056863 ; 9 : 99.1218444911693 ; 10 : -44.2133032061989 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-7-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 357 pihat0 estimated by ASH: 0.07619716 Unnormalized w: 0 : 1 ; 1 : 0.00370167318278368 ; 2 : 0.39411523441055 ; 3 : -0.0180828275775568 ; 4 : 0.0194176203907137 ; 5 : -0.00375358465692172 ; 6 : -0.00227753645456231 ; 7 : -0.00032592434598118 ; 8 : -0.000130598234701831 ; 9 : -4.35362529225419e-05 ; 10 : 3.57929373928491e-09 ; Normalized w: 0 : 1 ; 1 : 0.00370167318278368 ; 2 : 0.557363109641251 ; 3 : -0.0442937006717421 ; 4 : 0.0951265239526212 ; 5 : -0.0411184597620263 ; 6 : -0.0611127160036223 ; 7 : -0.0231383332089507 ; 8 : -0.0262239174026249 ; 9 : -0.0262260306182651 ; 10 : 6.81834319444681e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-7-5.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-10" class="section level3"> <h3><span class="math inline">\(\lambda = 10\)</span></h3> <pre class="r"><code>CorNullPlot("typical", L, lambda = 10, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 3 pihat0 estimated by ASH: 0.184423 Unnormalized w: 0 : 1 ; 1 : -0.0360231032814232 ; 2 : 0.198004631503733 ; 3 : 0.00848396367266838 ; 4 : -0.0192673173429187 ; 5 : -0.000913693546826654 ; 6 : -6.98930940597347e-10 ; 7 : -0.00013786898239914 ; 8 : -1.4550127334419e-09 ; 9 : -4.03039794052092e-05 ; 10 : 3.16144550026949e-11 ; Normalized w: 0 : 1 ; 1 : -0.0360231032814232 ; 2 : 0.280020835285267 ; 3 : 0.0207813819943463 ; 4 : -0.0943901924048558 ; 5 : -0.0100090113248772 ; 6 : -1.87542851370424e-08 ; 7 : -0.00978772679385683 ; 8 : -2.92164238120541e-07 ; 9 : -0.0242789245045857 ; 10 : 6.02236697558202e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-8-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 489 Number of False Discoveries by ASH at lfsr = 0.05: 1446 pihat0 estimated by ASH: 0.1522796 Unnormalized w: 0 : 1 ; 1 : 0.0504759960297731 ; 2 : 0.686491721129383 ; 3 : -0.111934208775094 ; 4 : 0.133707257997524 ; 5 : -0.0309742814883289 ; 6 : 0.00706330717764512 ; 7 : -0.00238881538932786 ; 8 : 1.14874587282051e-10 ; 9 : -5.83139706773415e-05 ; 10 : -3.37001119646057e-11 ; Normalized w: 0 : 1 ; 1 : 0.0504759960297731 ; 2 : 0.970845902478022 ; 3 : -0.274181696261143 ; 4 : 0.655029114001198 ; 5 : -0.339306253473448 ; 6 : 0.18952841994212 ; 7 : -0.169589069164318 ; 8 : 2.3066634058438e-08 ; 9 : -0.0351280571430325 ; 10 : -6.41967230976329e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-8-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0194979034611927 ; 2 : 0.881399833370166 ; 3 : 0.0202952891320483 ; 4 : 0.149606345019525 ; 5 : -0.0125010098851659 ; 6 : 0.00328865844826621 ; 7 : -0.00441151119171934 ; 8 : -7.86344085887155e-05 ; 9 : -0.000263759546136583 ; 10 : 4.02706012758681e-11 ; Normalized w: 0 : 1 ; 1 : 0.0194979034611927 ; 2 : 1.24648759822547 ; 3 : 0.0497131025557711 ; 4 : 0.732918415161216 ; 5 : -0.136941702114008 ; 6 : 0.0882439661412266 ; 7 : -0.313186226090982 ; 8 : -0.0157896639303183 ; 9 : -0.15888748958586 ; 10 : 7.6713117208551e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-8-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9998824 Unnormalized w: 0 : 1 ; 1 : 0.157079819472207 ; 2 : -0.176247923530239 ; 3 : 0.259270042791677 ; 4 : -0.0303625113757191 ; 5 : 0.127659806187516 ; 6 : -0.00915615359204601 ; 7 : 0.0223863800659267 ; 8 : -6.59829790247414e-10 ; 9 : 0.00116297535962442 ; 10 : 1.6560385410784e-05 ; Normalized w: 0 : 1 ; 1 : 0.157079819472207 ; 2 : -0.24925220379656 ; 3 : 0.635079310429168 ; 4 : -0.148745320359923 ; 5 : 1.3984431107128 ; 6 : -0.245685382130925 ; 7 : 1.58927532629776 ; 8 : -1.3249277035593e-07 ; 9 : 0.700570796574129 ; 10 : 0.031546556216868 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-8-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 357 pihat0 estimated by ASH: 0.07619716 Unnormalized w: 0 : 1 ; 1 : 0.0037421572469342 ; 2 : 0.388630237002326 ; 3 : -0.0184459635481736 ; 4 : 0.0207870740897271 ; 5 : -0.0037246892167014 ; 6 : -0.000505318351905671 ; 7 : -0.00023837133681814 ; 8 : 1.80694742300713e-10 ; 9 : -3.21365453502741e-05 ; 10 : 8.51227164805379e-12 ; Normalized w: 0 : 1 ; 1 : 0.0037421572469342 ; 2 : 0.54960615191696 ; 3 : -0.0451831985070036 ; 4 : 0.101835449530521 ; 5 : -0.0408019260736721 ; 6 : -0.0135591142216709 ; 7 : -0.0169226861594427 ; 8 : 3.62832162930918e-08 ; 9 : -0.0193589012775412 ; 10 : 1.62153747885429e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-8-5.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-100" class="section level3"> <h3><span class="math inline">\(\lambda = 100\)</span></h3> <pre class="r"><code>CorNullPlot("typical", L, lambda = 100, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 3 pihat0 estimated by ASH: 0.184423 Unnormalized w: 0 : 1 ; 1 : -0.0339029123785526 ; 2 : 0.191348166480557 ; 3 : 0.0110728235529016 ; 4 : -0.00672709448200233 ; 5 : 0.000170545146738018 ; 6 : 1.6210790987194e-10 ; 7 : -2.57099814035759e-05 ; 8 : -3.73974432587683e-12 ; 9 : -4.34050545775016e-05 ; 10 : 9.55207011029823e-14 ; Normalized w: 0 : 1 ; 1 : -0.0339029123785526 ; 2 : 0.270607172172028 ; 3 : 0.0271227677164805 ; 4 : -0.0329558978647961 ; 5 : 0.00186822847882882 ; 6 : 4.3498116739688e-09 ; 7 : -0.00182522761446675 ; 8 : -7.50934700860504e-10 ; 9 : -0.0261469973624583 ; 10 : 1.81961294527458e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-9-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 489 Number of False Discoveries by ASH at lfsr = 0.05: 1446 pihat0 estimated by ASH: 0.1522796 Unnormalized w: 0 : 1 ; 1 : 0.0762627046050676 ; 2 : 0.572325279030854 ; 3 : -0.0742295791781891 ; 4 : 0.0658408653406101 ; 5 : -0.016034236226993 ; 6 : 3.27433486078147e-09 ; 7 : -0.000630588723767359 ; 8 : -5.65549557412152e-11 ; 9 : -1.3162188080067e-05 ; 10 : -2.96109552393859e-12 ; Normalized w: 0 : 1 ; 1 : 0.0762627046050676 ; 2 : 0.809390171694399 ; 3 : -0.181824592808086 ; 4 : 0.322553048615586 ; 5 : -0.175646257477812 ; 6 : 8.78596239576562e-08 ; 7 : -0.0447673584015679 ; 8 : -1.13561449850589e-08 ; 9 : -0.00792883917238705 ; 10 : -5.64071210254656e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-9-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0132006489023589 ; 2 : 0.752373085029163 ; 3 : 0.0203345251933944 ; 4 : 0.0867415022867811 ; 5 : -0.00760820428774983 ; 6 : -1.10494922428467e-09 ; 7 : -0.00294317971105688 ; 8 : -1.58067898541077e-11 ; 9 : -0.000164456475629658 ; 10 : 2.12731019116624e-13 ; Normalized w: 0 : 1 ; 1 : 0.0132006489023589 ; 2 : 1.06401622081273 ; 3 : 0.0498092108855858 ; 4 : 0.424944840250148 ; 5 : -0.0833437022101621 ; 6 : -2.96488989262341e-08 ; 7 : -0.208945031839351 ; 8 : -3.17397821250152e-09 ; 9 : -0.0990677946700876 ; 10 : 4.05240028366978e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-9-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9998824 Unnormalized w: 0 : 1 ; 1 : 0.108378799022329 ; 2 : -0.118544204689578 ; 3 : 0.149535650571497 ; 4 : 1.04844549405109e-09 ; 5 : 0.0707641605237991 ; 6 : -9.1503517984161e-11 ; 7 : 0.0127375051159948 ; 8 : 5.05937935302799e-13 ; 9 : 0.000656454459567348 ; 10 : -4.32761979200679e-14 ; Normalized w: 0 : 1 ; 1 : 0.108378799022329 ; 2 : -0.167646822012733 ; 3 : 0.36628604225529 ; 4 : 5.13631296709075e-09 ; 5 : 0.775182539636027 ; 6 : -2.4552970367155e-09 ; 7 : 0.90427315804638 ; 8 : 1.01591531130008e-10 ; 9 : 0.395445028003221 ; 10 : -8.24386013171354e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-9-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 357 pihat0 estimated by ASH: 0.07619716 Unnormalized w: 0 : 1 ; 1 : 0.00731060610766733 ; 2 : 0.336253769001316 ; 3 : -0.014871486629131 ; 4 : 2.14561337556813e-07 ; 5 : -0.00280073551495972 ; 6 : -2.10100795862411e-09 ; 7 : -0.000291179301407538 ; 8 : 2.33753552855575e-11 ; 9 : -4.88929337454658e-05 ; 10 : -2.42600452715082e-13 ; Normalized w: 0 : 1 ; 1 : 0.00731060610766733 ; 2 : 0.475534640520731 ; 3 : -0.0364275539579937 ; 4 : 1.05113159108651e-06 ; 5 : -0.0306805203829858 ; 6 : -5.63759594010189e-08 ; 7 : -0.0206716797397704 ; 8 : 4.69373408962992e-09 ; 9 : -0.0294528695362634 ; 10 : -4.62139535401769e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-9-5.png" width="672" style="display: block; margin: auto;" /></p> </div> </div> <div id="hostile" class="section level2"> <h2>Hostile</h2> <p>All “hostile” data sets are inflated.</p> <div id="no-regularization-lambda-0-1" class="section level3"> <h3>No regularization: <span class="math inline">\(\lambda = 0\)</span></h3> <pre class="r"><code>CorNullPlot("hostile", L, lambda = 0, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0227244539615043 ; 2 : 0.92101434792072 ; 3 : 0.0222103145256307 ; 4 : 0.175694879344268 ; 5 : -0.0134165085467778 ; 6 : 0.00392982154182872 ; 7 : -0.00480255115990118 ; 8 : -0.000586133715906366 ; 9 : -0.000291508028046953 ; 10 : 2.65975448800262e-06 ; Normalized w: 0 : 1 ; 1 : 0.0227244539615043 ; 2 : 1.30251098196969 ; 3 : 0.0544039376145207 ; 4 : 0.860725609626624 ; 5 : -0.146970487480621 ; 6 : 0.105448177283665 ; 7 : -0.340947309892716 ; 8 : -0.117694716072657 ; 9 : -0.175603042426075 ; 10 : 0.00506667522509486 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 408 Number of False Discoveries by ASH at lfsr = 0.05: 2448 pihat0 estimated by ASH: 0.03139009 Unnormalized w: 0 : 1 ; 1 : 0.0154288916215935 ; 2 : 0.952920646422686 ; 3 : 0.0299159225977431 ; 4 : 0.141467724356241 ; 5 : 0.00918576726155382 ; 6 : -0.0084931811923254 ; 7 : 0.000415049492994605 ; 8 : -0.00154678887803449 ; 9 : 2.66655506029959e-05 ; 10 : -3.79757318599317e-05 ; Normalized w: 0 : 1 ; 1 : 0.0154288916215935 ; 2 : 1.3476333020363 ; 3 : 0.0732787455490672 ; 4 : 0.693047479490981 ; 5 : 0.10062503874291 ; 6 : -0.227895965895148 ; 7 : 0.0294655909738936 ; 8 : -0.310592741697347 ; 9 : 0.0160632001980348 ; 10 : -0.0723415264970773 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 331 Number of False Discoveries by ASH at lfsr = 0.05: 1822 pihat0 estimated by ASH: 0.04301549 Unnormalized w: 0 : 1 ; 1 : 0.0071244364456378 ; 2 : 0.780475489960925 ; 3 : -0.110297574001406 ; 4 : 0.107848037343858 ; 5 : -0.0224625109915279 ; 6 : -0.0128392334784825 ; 7 : -0.000573937582144242 ; 8 : -0.00292373634747594 ; 9 : 1.6026836774617e-06 ; 10 : -0.000112993982390249 ; Normalized w: 0 : 1 ; 1 : 0.0071244364456378 ; 2 : 1.10375902300253 ; 3 : -0.270172776170312 ; 4 : 0.528345322506156 ; 5 : -0.246064479365351 ; 6 : -0.344512786042534 ; 7 : -0.0407455263178155 ; 8 : -0.587081599213887 ; 9 : 0.000965448985039801 ; 10 : -0.215246863477015 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 114 Number of False Discoveries by ASH at lfsr = 0.05: 1685 pihat0 estimated by ASH: 0.02583276 Unnormalized w: 0 : 1 ; 1 : 0.0458630182725496 ; 2 : 0.756062141050916 ; 3 : 0.000522286088833344 ; 4 : 0.0893796469651393 ; 5 : -0.00182535146538549 ; 6 : -0.00670505702133343 ; 7 : 0.00155750252807623 ; 8 : -0.00152348453369753 ; 9 : 0.000174010174048529 ; 10 : -6.54073091086348e-05 ; Normalized w: 0 : 1 ; 1 : 0.0458630182725496 ; 2 : 1.06923333387105 ; 3 : 0.00127933441739562 ; 4 : 0.437869056909381 ; 5 : -0.0199957234593349 ; 6 : -0.179915559512566 ; 7 : 0.11057171062174 ; 8 : -0.305913266493032 ; 9 : 0.104822896922382 ; 10 : -0.124597061155712 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 79 Number of False Discoveries by ASH at lfsr = 0.05: 1814 pihat0 estimated by ASH: 0.01606004 Unnormalized w: 0 : 1 ; 1 : 0.0352466614174826 ; 2 : 0.76764549272395 ; 3 : 0.0294087568867211 ; 4 : 0.063983964946533 ; 5 : -0.00272625339888582 ; 6 : -0.0166812243244297 ; 7 : -0.00175235100172814 ; 8 : -0.00249016360710572 ; 9 : -0.000110171636609466 ; 10 : -0.000108201442747287 ; Normalized w: 0 : 1 ; 1 : 0.0352466614174826 ; 2 : 1.08561466690479 ; 3 : 0.0720364483420274 ; 4 : 0.313456131678262 ; 5 : -0.0298646096808979 ; 6 : -0.447604218448174 ; 7 : -0.124404580010619 ; 8 : -0.500020883902863 ; 9 : -0.0663668671744645 ; 10 : -0.206117358485555 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 35 Number of False Discoveries by ASH at lfsr = 0.05: 1137 pihat0 estimated by ASH: 0.04829662 Unnormalized w: 0 : 1 ; 1 : 0.0155701631204155 ; 2 : 0.610648478330274 ; 3 : 0.0551077467439953 ; 4 : 0.0685970418092259 ; 5 : 0.0169280711830408 ; 6 : 4.77079679243324e-05 ; 7 : 0.000459249911420758 ; 8 : 8.16221666285944e-05 ; 9 : -9.11879625666256e-05 ; 10 : 1.76195080904653e-05 ; Normalized w: 0 : 1 ; 1 : 0.0155701631204155 ; 2 : 0.863587359897166 ; 3 : 0.134985860397309 ; 4 : 0.336055500593935 ; 5 : 0.185437728840093 ; 6 : 0.00128013911216624 ; 7 : 0.0326035093961596 ; 8 : 0.0163896009833396 ; 9 : -0.0549311926900185 ; 10 : 0.0335641223740764 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 28 Number of False Discoveries by ASH at lfsr = 0.05: 1653 pihat0 estimated by ASH: 0.02316832 Unnormalized w: 0 : 1 ; 1 : -0.0454462107392084 ; 2 : 0.731635414118698 ; 3 : -0.00197063805379626 ; 4 : 0.0671792199803835 ; 5 : -0.0152667648045991 ; 6 : -0.00791142637750884 ; 7 : -0.00214165049860173 ; 8 : -0.000257366565348708 ; 9 : 5.48859085063099e-06 ; 10 : 3.10611293325516e-05 ; Normalized w: 0 : 1 ; 1 : -0.0454462107392084 ; 2 : 1.03468872535912 ; 3 : -0.00482705769951215 ; 4 : 0.329109620540248 ; 5 : -0.167239029272098 ; 6 : -0.212285846149136 ; 7 : -0.152042102606915 ; 8 : -0.0516787961744721 ; 9 : 0.003306300888041 ; 10 : 0.0591696170314166 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 16 Number of False Discoveries by ASH at lfsr = 0.05: 1506 pihat0 estimated by ASH: 0.05110069 Unnormalized w: 0 : 1 ; 1 : -0.0307690864088977 ; 2 : 0.712131187119833 ; 3 : -0.0222867102459425 ; 4 : 0.0797018945257774 ; 5 : -0.000212502676097517 ; 6 : -0.00304346991756197 ; 7 : 0.000776824043771723 ; 8 : -6.59826931703547e-05 ; 9 : 7.95517863468703e-05 ; 10 : 4.39916990470856e-05 ; Normalized w: 0 : 1 ; 1 : -0.0307690864088977 ; 2 : 1.00710558301372 ; 3 : -0.0545910681478169 ; 4 : 0.390457946242557 ; 5 : -0.00232785018457648 ; 6 : -0.081664867477731 ; 7 : 0.055149036244603 ; 8 : -0.0132492196364877 ; 9 : 0.04792161576658 ; 10 : 0.0838015887094456 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 12 Number of False Discoveries by ASH at lfsr = 0.05: 795 pihat0 estimated by ASH: 0.04316169 Unnormalized w: 0 : 1 ; 1 : -0.0344695490777356 ; 2 : 0.522571163393063 ; 3 : 0.0313607610699586 ; 4 : 0.0339792130749094 ; 5 : 0.0103080681023228 ; 6 : -0.00198873199841041 ; 7 : 4.4467825695412e-05 ; 8 : 0.00021300079871282 ; 9 : -8.34952321992777e-06 ; 10 : 1.98696121319262e-05 ; Normalized w: 0 : 1 ; 1 : -0.0344695490777356 ; 2 : 0.739027226575557 ; 3 : 0.0768178625667375 ; 4 : 0.166463467789669 ; 5 : 0.112919228478833 ; 6 : -0.0533632792496961 ; 7 : 0.00315690245514029 ; 8 : 0.0427702209366833 ; 9 : -0.00502971286948678 ; 10 : 0.0378504376908398 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 11 Number of False Discoveries by ASH at lfsr = 0.05: 1028 pihat0 estimated by ASH: 0.03156173 Unnormalized w: 0 : 1 ; 1 : 0.0104975596282685 ; 2 : 0.579125687844271 ; 3 : 0.0712077182038672 ; 4 : 0.0472520309498492 ; 5 : 0.00766045653227167 ; 6 : -0.0029999092141953 ; 7 : -0.00143274142610634 ; 8 : 0.000281761349107555 ; 9 : -9.24875783860482e-05 ; 10 : 6.5126905978099e-05 ; Normalized w: 0 : 1 ; 1 : 0.0104975596282685 ; 2 : 0.819007402068015 ; 3 : 0.174422575347368 ; 4 : 0.231486730274658 ; 5 : 0.0839160968702599 ; 6 : -0.080496011151224 ; 7 : -0.101714551024765 ; 8 : 0.056577229876945 ; 9 : -0.0557140750463113 ; 10 : 0.124062909751538 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 9 Number of False Discoveries by ASH at lfsr = 0.05: 614 pihat0 estimated by ASH: 0.04794909 Unnormalized w: 0 : 1 ; 1 : -0.012281703930413 ; 2 : 0.484378296227544 ; 3 : 0.0440712708998003 ; 4 : 0.0237103488082757 ; 5 : 0.00836396915392277 ; 6 : -0.00537574147672548 ; 7 : -0.0013054623533153 ; 8 : -0.000847592148032516 ; 9 : -0.000133525903750732 ; 10 : -7.55297387329877e-05 ; Normalized w: 0 : 1 ; 1 : -0.012281703930413 ; 2 : 0.685014355844165 ; 3 : 0.107952126020479 ; 4 : 0.116156512407366 ; 5 : 0.091622691517618 ; 6 : -0.144246280457079 ; 7 : -0.0926786332325558 ; 8 : -0.17019515257511 ; 9 : -0.0804353660460534 ; 10 : -0.143879691799561 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 1307 pihat0 estimated by ASH: 0.05151585 Unnormalized w: 0 : 1 ; 1 : 0.0316501559909339 ; 2 : 0.63639003184346 ; 3 : 0.150623605408836 ; 4 : 0.0710578049167553 ; 5 : 0.0205410586065359 ; 6 : -0.00232338209328991 ; 7 : -0.00256591761351304 ; 8 : -0.000399841651727246 ; 9 : -0.000252319687963247 ; 10 : -2.53525509589763e-06 ; Normalized w: 0 : 1 ; 1 : 0.0316501559909339 ; 2 : 0.899991413992067 ; 3 : 0.368950976469964 ; 4 : 0.348110728576561 ; 5 : 0.225016023076707 ; 6 : -0.0623428835796239 ; 7 : -0.182162079820845 ; 8 : -0.0802875664664511 ; 9 : -0.151996173715008 ; 10 : -0.00482951123557513 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 689 pihat0 estimated by ASH: 0.04567195 Unnormalized w: 0 : 1 ; 1 : -0.0114149221900095 ; 2 : 0.494122018875004 ; 3 : 0.0407811769078796 ; 4 : 0.0293810611708229 ; 5 : 0.00420083938040471 ; 6 : -0.000169735520043324 ; 7 : -0.00059122469963324 ; 8 : 0.000651774557153136 ; 9 : -0.000106315927362571 ; 10 : 5.69253997014753e-05 ; Normalized w: 0 : 1 ; 1 : -0.0114149221900095 ; 2 : 0.698794060560205 ; 3 : 0.0998930745344773 ; 4 : 0.143937215940032 ; 5 : 0.0460178897820737 ; 6 : -0.00455448193215781 ; 7 : -0.0419727899132323 ; 8 : 0.130875292387675 ; 9 : -0.0640442063578776 ; 10 : 0.108439524642999 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 6 Number of False Discoveries by ASH at lfsr = 0.05: 1392 pihat0 estimated by ASH: 0.0308234 Unnormalized w: 0 : 1 ; 1 : 0.0370556597109904 ; 2 : 0.682882414087328 ; 3 : 0.0463829983693932 ; 4 : 0.0372206294202173 ; 5 : 0.00893458882312159 ; 6 : -0.00365903877733973 ; 7 : -0.0015718648201254 ; 8 : 0.000865302913818613 ; 9 : -0.000182427628339264 ; 10 : 6.67747079772481e-05 ; Normalized w: 0 : 1 ; 1 : 0.0370556597109904 ; 2 : 0.965741571508379 ; 3 : 0.113614678745358 ; 4 : 0.182343099969512 ; 5 : 0.0978735168091446 ; 6 : -0.0981823132612724 ; 7 : -0.111591332209313 ; 8 : 0.173751446120518 ; 9 : -0.109893531144151 ; 10 : 0.127201875247267 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 4 Number of False Discoveries by ASH at lfsr = 0.05: 1149 pihat0 estimated by ASH: 0.02083846 Unnormalized w: 0 : 1 ; 1 : -0.00719663878755195 ; 2 : 0.590959201932682 ; 3 : -0.0172003042045236 ; 4 : 0.00678574739612099 ; 5 : -0.0053623338822082 ; 6 : -0.00164100416474657 ; 7 : -0.000531083271301875 ; 8 : 0.00140201962800745 ; 9 : -8.24861592639277e-05 ; 10 : 4.67626846601773e-05 ; Normalized w: 0 : 1 ; 1 : -0.00719663878755195 ; 2 : 0.83574251818238 ; 3 : -0.042131968721731 ; 4 : 0.0332432372878321 ; 5 : -0.0587414245631936 ; 6 : -0.0440327623648031 ; 7 : -0.0377031720538972 ; 8 : 0.281523307000802 ; 9 : -0.0496892679828852 ; 10 : 0.0890801526589662 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 508 pihat0 estimated by ASH: 0.03271534 Unnormalized w: 0 : 1 ; 1 : 0.0111841878604641 ; 2 : 0.450895624947067 ; 3 : 0.038980313866716 ; 4 : 0.00296353543192371 ; 5 : 0.00351438732862135 ; 6 : -0.00390912755146694 ; 7 : -0.00142442285360721 ; 8 : -2.45080424286452e-05 ; 9 : -0.000143353997765883 ; 10 : 1.92180553113022e-05 ; Normalized w: 0 : 1 ; 1 : 0.0111841878604641 ; 2 : 0.637662708014834 ; 3 : 0.0954818789869898 ; 4 : 0.0145182992857433 ; 5 : 0.0384981843139247 ; 6 : -0.104892899253569 ; 7 : -0.101123990961728 ; 8 : -0.00492117586287565 ; 9 : -0.0863557628936899 ; 10 : 0.0366092604259125 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 662 pihat0 estimated by ASH: 0.02787007 Unnormalized w: 0 : 1 ; 1 : 0.0350137302803461 ; 2 : 0.470765168889938 ; 3 : -0.0160615011202655 ; 4 : -0.0399330192505554 ; 5 : 0.0329287497698357 ; 6 : -0.0240277513400892 ; 7 : 0.00930686045653883 ; 8 : -0.00274549884057576 ; 9 : 0.000566764428394551 ; 10 : -0.00012523163696814 ; Normalized w: 0 : 1 ; 1 : 0.0350137302803461 ; 2 : 0.665762486537011 ; 3 : -0.0393424822477908 ; 4 : -0.195631042105197 ; 5 : 0.360716380787642 ; 6 : -0.644732224114812 ; 7 : 0.660721547892703 ; 8 : -0.551291791873294 ; 9 : 0.341416182023392 ; 10 : -0.238558872740559 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 227 pihat0 estimated by ASH: 0.0531628 Unnormalized w: 0 : 1 ; 1 : 0.00286426406281591 ; 2 : 0.386810691223569 ; 3 : -0.0143590887965683 ; 4 : -0.0255496121929127 ; 5 : 0.00347603061961416 ; 6 : -4.76789154803652e-05 ; 7 : 0.001068930017731 ; 8 : 0.00076319617815179 ; 9 : 9.22925378517028e-05 ; 10 : 1.63550318067118e-07 ; Normalized w: 0 : 1 ; 1 : 0.00286426406281591 ; 2 : 0.547032925599282 ; 3 : -0.035172440722907 ; 4 : -0.125167025997255 ; 5 : 0.0380780076188267 ; 6 : -0.00127935955329076 ; 7 : 0.0758865032093603 ; 8 : 0.153248576319164 ; 9 : 0.0555965835608901 ; 10 : 0.000311553697284798 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 1340 pihat0 estimated by ASH: 0.03239883 Unnormalized w: 0 : 1 ; 1 : 0.0237520134361132 ; 2 : 0.651112971445468 ; 3 : 0.0517998517501412 ; 4 : 0.0324107063786448 ; 5 : 0.00273028493662741 ; 6 : -0.00897163791412935 ; 7 : -0.00341090892964708 ; 8 : -0.000654091985324589 ; 9 : -0.000329087147961516 ; 10 : -2.8333501939919e-05 ; Normalized w: 0 : 1 ; 1 : 0.0237520134361132 ; 2 : 0.920812794855227 ; 3 : 0.12688320553966 ; 4 : 0.158779385661696 ; 5 : 0.0299087729641479 ; 6 : -0.240734306946092 ; 7 : -0.242150512328148 ; 8 : -0.131340628271375 ; 9 : -0.198240524600764 ; 10 : -0.0539736479313062 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 193 pihat0 estimated by ASH: 0.0465218 Unnormalized w: 0 : 1 ; 1 : 0.0232306825787541 ; 2 : 0.347387389370562 ; 3 : 0.0676187492916692 ; 4 : -0.0186668985504176 ; 5 : -1.39143386157503e-05 ; 6 : -0.00637803149808692 ; 7 : -0.00224350173369652 ; 8 : -0.00103131474862092 ; 9 : -0.000100620230928565 ; 10 : -9.227370323808e-05 ; Normalized w: 0 : 1 ; 1 : 0.0232306825787541 ; 2 : 0.491279957445232 ; 3 : 0.165631432809771 ; 4 : -0.0914487530576442 ; 5 : -0.000152423942652233 ; 6 : -0.171140543908286 ; 7 : -0.159272823000851 ; 8 : -0.207086357987078 ; 9 : -0.0606131460565619 ; 10 : -0.175775955349633 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-10-20.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-1-1" class="section level3"> <h3><span class="math inline">\(\lambda = 1\)</span></h3> <pre class="r"><code>CorNullPlot("hostile", L, lambda = 1, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0223556913438548 ; 2 : 0.916740955025879 ; 3 : 0.0218891094396244 ; 4 : 0.172881230445589 ; 5 : -0.0134617737282905 ; 6 : 0.00376825719933721 ; 7 : -0.00480328049020991 ; 8 : -0.000564405807267297 ; 9 : -0.000291745094113606 ; 10 : 8.09167312092846e-10 ; Normalized w: 0 : 1 ; 1 : 0.0223556913438548 ; 2 : 1.29646749178046 ; 3 : 0.0536171490510185 ; 4 : 0.846941601392408 ; 5 : -0.147466342700302 ; 6 : 0.101112951053052 ; 7 : -0.340999087208252 ; 8 : -0.113331786644218 ; 9 : -0.175745849891238 ; 10 : 1.54141594332499e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 408 Number of False Discoveries by ASH at lfsr = 0.05: 2448 pihat0 estimated by ASH: 0.03139009 Unnormalized w: 0 : 1 ; 1 : 0.0160250568304281 ; 2 : 0.9504830866948 ; 3 : 0.0320675120076468 ; 4 : 0.14407168991174 ; 5 : 0.0107790382487586 ; 6 : -0.00526204614013953 ; 7 : 0.000756481972585031 ; 8 : -0.000849111882761341 ; 9 : 4.68462535131963e-05 ; 10 : 1.29313347330595e-09 ; Normalized w: 0 : 1 ; 1 : 0.0160250568304281 ; 2 : 1.34418607201003 ; 3 : 0.0785490417393073 ; 4 : 0.705804253328493 ; 5 : 0.118078447941122 ; 6 : -0.141195514441109 ; 7 : 0.0537048924514755 ; 8 : -0.170500312886761 ; 9 : 0.0282199591493084 ; 10 : 2.46334289931413e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 331 Number of False Discoveries by ASH at lfsr = 0.05: 1822 pihat0 estimated by ASH: 0.04301549 Unnormalized w: 0 : 1 ; 1 : 0.00800939747755179 ; 2 : 0.772931414214873 ; 3 : -0.106128587896109 ; 4 : 0.106527061288674 ; 5 : -0.0193302012185171 ; 6 : -0.00828037456931695 ; 7 : 0.000169920604917084 ; 8 : -0.00139066109304468 ; 9 : 5.67707086212788e-05 ; 10 : -5.56172208067091e-10 ; Normalized w: 0 : 1 ; 1 : 0.00800939747755179 ; 2 : 1.09309008876689 ; 3 : -0.259960887467581 ; 4 : 0.521873887910883 ; 5 : -0.211751744969913 ; 6 : -0.222185764993839 ; 7 : 0.0120631662657842 ; 8 : -0.2792425312816 ; 9 : 0.0341984034586349 ; 10 : -1.05947521104326e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 114 Number of False Discoveries by ASH at lfsr = 0.05: 1685 pihat0 estimated by ASH: 0.02583276 Unnormalized w: 0 : 1 ; 1 : 0.0468410510368395 ; 2 : 0.755754656003814 ; 3 : 0.00152739035621532 ; 4 : 0.0950718054969482 ; 5 : -0.00162974613494927 ; 6 : -0.00174587263329282 ; 7 : 0.00157609614107534 ; 8 : -0.000428763024102919 ; 9 : 0.000175781331705588 ; 10 : 3.67761976479942e-11 ; Normalized w: 0 : 1 ; 1 : 0.0468410510368395 ; 2 : 1.06879848434721 ; 3 : 0.00374132701077537 ; 4 : 0.465754824785304 ; 5 : -0.0178529744223714 ; 6 : -0.0468466786571918 ; 7 : 0.111891726197245 ; 8 : -0.0860949319494669 ; 9 : 0.105889833827275 ; 10 : 7.00564846630688e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 79 Number of False Discoveries by ASH at lfsr = 0.05: 1814 pihat0 estimated by ASH: 0.01606004 Unnormalized w: 0 : 1 ; 1 : 0.0360981599057933 ; 2 : 0.766706667103251 ; 3 : 0.0330500715335886 ; 4 : 0.0707762394225816 ; 5 : 0.00105602955835814 ; 6 : -0.00976762391923616 ; 7 : -0.000675158695623136 ; 8 : -0.000810026978642787 ; 9 : -3.07395198886815e-05 ; 10 : -3.1752817001347e-12 ; Normalized w: 0 : 1 ; 1 : 0.0360981599057933 ; 2 : 1.08428696697929 ; 3 : 0.0809558112197755 ; 4 : 0.34673134499676 ; 5 : 0.0115682242100995 ; 6 : -0.26209285274478 ; 7 : -0.0479315125147193 ; 8 : -0.162652126426702 ; 9 : -0.0185173398185105 ; 10 : -6.04872411921417e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 35 Number of False Discoveries by ASH at lfsr = 0.05: 1137 pihat0 estimated by ASH: 0.04829662 Unnormalized w: 0 : 1 ; 1 : 0.0155958690836745 ; 2 : 0.60877758371477 ; 3 : 0.0560325159085344 ; 4 : 0.0677202724819457 ; 5 : 0.0175329111032881 ; 6 : -0.000124217564025771 ; 7 : 0.00056431159268912 ; 8 : -4.73345914542686e-05 ; 9 : -8.61622929437318e-05 ; 10 : 1.50454483871259e-08 ; Normalized w: 0 : 1 ; 1 : 0.0155958690836745 ; 2 : 0.860941515358149 ; 3 : 0.13725107298029 ; 4 : 0.331760225646016 ; 5 : 0.192063418200074 ; 6 : -0.00333310700593268 ; 7 : 0.0400621488585222 ; 8 : -0.00950471053010591 ; 9 : -0.0519037533363884 ; 10 : 2.86606906529709e-05 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 28 Number of False Discoveries by ASH at lfsr = 0.05: 1653 pihat0 estimated by ASH: 0.02316832 Unnormalized w: 0 : 1 ; 1 : -0.0467537900187071 ; 2 : 0.728715830709401 ; 3 : -0.00454531684862811 ; 4 : 0.0678560947849051 ; 5 : -0.0165052214031922 ; 6 : -0.00657507131583426 ; 7 : -0.00233869772539313 ; 8 : -8.57153442382681e-05 ; 9 : -3.28397506708893e-06 ; 10 : 3.01661943643426e-05 ; Normalized w: 0 : 1 ; 1 : -0.0467537900187071 ; 2 : 1.03055981090521 ; 3 : -0.0111337069984141 ; 4 : 0.332425616321896 ; 5 : -0.180805641582909 ; 6 : -0.176427677029373 ; 7 : -0.166031067983752 ; 8 : -0.017211504524344 ; 9 : -0.00197825088007286 ; 10 : 0.0574648187682878 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 16 Number of False Discoveries by ASH at lfsr = 0.05: 1506 pihat0 estimated by ASH: 0.05110069 Unnormalized w: 0 : 1 ; 1 : -0.0308735233034481 ; 2 : 0.710414629721538 ; 3 : -0.0224290573030673 ; 4 : 0.0802203328578481 ; 5 : -8.15728257277138e-05 ; 6 : -0.00253347090141121 ; 7 : 0.00086434512182603 ; 8 : -0.000120288962542039 ; 9 : 8.86376362061075e-05 ; 10 : 2.82403852890122e-05 ; Normalized w: 0 : 1 ; 1 : -0.0308735233034481 ; 2 : 1.00467800426046 ; 3 : -0.0549397458041594 ; 4 : 0.392997764995902 ; 5 : -0.000893585534610132 ; 6 : -0.0679801578548776 ; 7 : 0.061362416410269 ; 8 : -0.0241538319821229 ; 9 : 0.0533948882832861 ; 10 : 0.0537962662104288 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 12 Number of False Discoveries by ASH at lfsr = 0.05: 795 pihat0 estimated by ASH: 0.04316169 Unnormalized w: 0 : 1 ; 1 : -0.0344491971673983 ; 2 : 0.520936039054011 ; 3 : 0.031757736259423 ; 4 : 0.0329279384845785 ; 5 : 0.0104107162019601 ; 6 : -0.00254902120037916 ; 7 : 3.1968927166989e-05 ; 8 : -1.36409251995725e-07 ; 9 : -1.06924717257244e-05 ; 10 : 2.86812841151204e-10 ; Normalized w: 0 : 1 ; 1 : -0.0344491971673983 ; 2 : 0.736714811559102 ; 3 : 0.07779024922147 ; 4 : 0.161313295137941 ; 5 : 0.114043682071961 ; 6 : -0.068397416161631 ; 7 : 0.00226956868440009 ; 8 : -2.73907604146168e-05 ; 9 : -0.00644109384798677 ; 10 : 5.46361524364291e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 11 Number of False Discoveries by ASH at lfsr = 0.05: 1028 pihat0 estimated by ASH: 0.03156173 Unnormalized w: 0 : 1 ; 1 : 0.0102619591643994 ; 2 : 0.577204176450881 ; 3 : 0.0716691788973413 ; 4 : 0.0463837601494875 ; 5 : 0.00774791950289155 ; 6 : -0.00354664115712136 ; 7 : -0.0015028275036553 ; 8 : -6.98406544085581e-06 ; 9 : -0.000101225663517891 ; 10 : 3.45077259999144e-05 ; Normalized w: 0 : 1 ; 1 : 0.0102619591643994 ; 2 : 0.816289974595229 ; 3 : 0.17555291858273 ; 4 : 0.227233089435769 ; 5 : 0.0848742057093583 ; 6 : -0.0951663686294624 ; 7 : -0.106690168942334 ; 8 : -0.00140238921049491 ; 9 : -0.0609778557538617 ; 10 : 0.0657351801404145 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 9 Number of False Discoveries by ASH at lfsr = 0.05: 614 pihat0 estimated by ASH: 0.04794909 Unnormalized w: 0 : 1 ; 1 : -0.0126799288193667 ; 2 : 0.486188521556034 ; 3 : 0.0437265990842193 ; 4 : 0.0284309423589625 ; 5 : 0.00940845797947052 ; 6 : -0.0020632828501766 ; 7 : -0.000839908561892715 ; 8 : 1.24668582342578e-08 ; 9 : -9.33124196200708e-05 ; 10 : -1.04035292420919e-05 ; Normalized w: 0 : 1 ; 1 : -0.0126799288193667 ; 2 : 0.687574401054668 ; 3 : 0.107107855943588 ; 4 : 0.139282603371877 ; 5 : 0.10306449333391 ; 6 : -0.0553636885176527 ; 7 : -0.0596275927519892 ; 8 : 2.50332526585696e-06 ; 9 : -0.0562109554622068 ; 10 : -0.0198181088150137 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 1307 pihat0 estimated by ASH: 0.05151585 Unnormalized w: 0 : 1 ; 1 : 0.0306804507050371 ; 2 : 0.634712838779934 ; 3 : 0.150255672592719 ; 4 : 0.0715689849145911 ; 5 : 0.0206710637611877 ; 6 : -0.00134610645675362 ; 7 : -0.00258223263719139 ; 8 : -0.000244952762316003 ; 9 : -0.000258568506140566 ; 10 : 9.58815036407773e-10 ; Normalized w: 0 : 1 ; 1 : 0.0306804507050371 ; 2 : 0.897619504814911 ; 3 : 0.368049728810852 ; 4 : 0.35061498889939 ; 5 : 0.226440158192601 ; 6 : -0.0361198265070298 ; 7 : -0.183320331601776 ; 8 : -0.0491861243085364 ; 9 : -0.155760431910079 ; 10 : 1.8264860205439e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 689 pihat0 estimated by ASH: 0.04567195 Unnormalized w: 0 : 1 ; 1 : -0.0107395958908629 ; 2 : 0.49119549307977 ; 3 : 0.0425074224662843 ; 4 : 0.0259082103162259 ; 5 : 0.00474546555839352 ; 6 : -0.00238060698745243 ; 7 : -0.00063182892294805 ; 8 : 6.86094327098021e-09 ; 9 : -0.000116844928262916 ; 10 : 3.09442899779814e-06 ; Normalized w: 0 : 1 ; 1 : -0.0107395958908629 ; 2 : 0.69465532808995 ; 3 : 0.104121495323315 ; 4 : 0.12692379084693 ; 5 : 0.0519839706439196 ; 6 : -0.0638783886198554 ; 7 : -0.0448554038091668 ; 8 : 1.3776664749953e-06 ; 9 : -0.0703868261621931 ; 10 : 0.00589470449610292 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 6 Number of False Discoveries by ASH at lfsr = 0.05: 1392 pihat0 estimated by ASH: 0.0308234 Unnormalized w: 0 : 1 ; 1 : 0.0395233563283826 ; 2 : 0.680264280751089 ; 3 : 0.0511438867100666 ; 4 : 0.0353532943160099 ; 5 : 0.0105267613164501 ; 6 : -0.0056843507574596 ; 7 : -0.00146725994667897 ; 8 : 8.65180076466989e-05 ; 9 : -0.000185202574268701 ; 10 : 2.45519292971495e-07 ; Normalized w: 0 : 1 ; 1 : 0.0395233563283826 ; 2 : 0.962038971836169 ; 3 : 0.125276425902373 ; 4 : 0.173195063601322 ; 5 : 0.11531489260985 ; 6 : -0.152527136419585 ; 7 : -0.104165122885192 ; 8 : 0.017372678057607 ; 9 : -0.111565145305318 ; 10 : 0.000467699753715108 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 4 Number of False Discoveries by ASH at lfsr = 0.05: 1149 pihat0 estimated by ASH: 0.02083846 Unnormalized w: 0 : 1 ; 1 : -0.00733293919888795 ; 2 : 0.585506635320233 ; 3 : -0.0182658004946831 ; 4 : 0.000900817247036314 ; 5 : -0.00665105236070717 ; 6 : -0.00456309511180789 ; 7 : -0.000973246314961311 ; 8 : 0.000722084782573559 ; 9 : -0.000121189542456088 ; 10 : 7.11918933506316e-11 ; Normalized w: 0 : 1 ; 1 : -0.00733293919888795 ; 2 : 0.828031424529312 ; 3 : -0.04474189095545 ; 4 : 0.00441308521347526 ; 5 : -0.0728586281821461 ; 6 : -0.122440690293593 ; 7 : -0.0690936341750258 ; 8 : 0.144993473603483 ; 9 : -0.0730040009810133 ; 10 : 1.35616352522115e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 508 pihat0 estimated by ASH: 0.03271534 Unnormalized w: 0 : 1 ; 1 : 0.0103611213527301 ; 2 : 0.449348604274889 ; 3 : 0.0376698222646347 ; 4 : 0.00233077225788051 ; 5 : 0.00299322662214977 ; 6 : -0.00389555766707583 ; 7 : -0.00149981007408626 ; 8 : -0.000113503792230453 ; 9 : -0.000146481027592927 ; 10 : 3.88311902097037e-06 ; Normalized w: 0 : 1 ; 1 : 0.0103611213527301 ; 2 : 0.635474890398968 ; 3 : 0.0922718432496881 ; 4 : 0.0114184054768838 ; 5 : 0.0327891548135284 ; 6 : -0.104528781046225 ; 7 : -0.10647595269349 ; 8 : -0.0227913805966197 ; 9 : -0.0882394707114983 ; 10 : 0.00739711241334159 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 662 pihat0 estimated by ASH: 0.02787007 Unnormalized w: 0 : 1 ; 1 : 0.0311809657713659 ; 2 : 0.479099518096388 ; 3 : -0.0340921650111574 ; 4 : -0.0190169406633145 ; 5 : 0.0149671032218498 ; 6 : -0.0123102633908051 ; 7 : 0.0041468828899631 ; 8 : -0.000554980614344054 ; 9 : 0.000172179597824328 ; 10 : -3.11742492225663e-08 ; Normalized w: 0 : 1 ; 1 : 0.0311809657713659 ; 2 : 0.677549036218326 ; 3 : -0.0835084085041016 ; 4 : -0.0931636021878106 ; 5 : 0.163956401102308 ; 6 : -0.330319029153206 ; 7 : 0.294399480338309 ; 8 : -0.111439222925518 ; 9 : 0.103720166556717 ; 10 : -5.93851037414825e-05 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 227 pihat0 estimated by ASH: 0.0531628 Unnormalized w: 0 : 1 ; 1 : 0.00268257272570874 ; 2 : 0.386084316089081 ; 3 : -0.0146004362562152 ; 4 : -0.0256328742061264 ; 5 : 0.00345646277117476 ; 6 : -0.000247660785930062 ; 7 : 0.00106365565313052 ; 8 : 0.0007123441528231 ; 9 : 9.08119481819637e-05 ; 10 : -6.80147235458954e-10 ; Normalized w: 0 : 1 ; 1 : 0.00268257272570874 ; 2 : 0.54600567603272 ; 3 : -0.0357636188497589 ; 4 : -0.125574924891916 ; 5 : 0.0378636525789846 ; 6 : -0.00664543623240772 ; 7 : 0.075512060467981 ; 8 : 0.143037570672568 ; 9 : 0.0547046834223836 ; 10 : -1.29564031675139e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 1340 pihat0 estimated by ASH: 0.03239883 Unnormalized w: 0 : 1 ; 1 : 0.0226975128282614 ; 2 : 0.650247039913163 ; 3 : 0.0515460203709436 ; 4 : 0.0348890000926562 ; 5 : 0.00416045591030353 ; 6 : -0.00657513883441439 ; 7 : -0.00282017341343353 ; 8 : -0.000144622303014227 ; 9 : -0.000278135537474042 ; 10 : 2.60602458287274e-10 ; Normalized w: 0 : 1 ; 1 : 0.0226975128282614 ; 2 : 0.919588182738155 ; 3 : 0.126261448179919 ; 4 : 0.170920495725845 ; 5 : 0.0455755110315787 ; 6 : -0.176429488742992 ; 7 : -0.200212450992589 ; 8 : -0.0290399279705525 ; 9 : -0.167547518037433 ; 10 : 4.96432292889751e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 193 pihat0 estimated by ASH: 0.0465218 Unnormalized w: 0 : 1 ; 1 : 0.0214845657823466 ; 2 : 0.351396401277223 ; 3 : 0.063230593886195 ; 4 : -0.010037839370954 ; 5 : -0.00161352166619517 ; 6 : -0.00169194380273747 ; 7 : -0.00220701437405813 ; 8 : -2.20452212744048e-10 ; 9 : -7.64797879258848e-05 ; 10 : -1.69006427401707e-05 ; Normalized w: 0 : 1 ; 1 : 0.0214845657823466 ; 2 : 0.496949556455348 ; 3 : 0.154882691154323 ; 4 : -0.0491751691577139 ; 5 : -0.0176752442719683 ; 6 : -0.0453996162843658 ; 7 : -0.156682477432507 ; 8 : -4.42664529993434e-08 ; 9 : -0.0460710586046817 ; 10 : -0.0321947263351014 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-11-20.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-10-1" class="section level3"> <h3><span class="math inline">\(\lambda = 10\)</span></h3> <pre class="r"><code>CorNullPlot("hostile", L, lambda = 10, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0194979034611927 ; 2 : 0.881399833370166 ; 3 : 0.0202952891320483 ; 4 : 0.149606345019525 ; 5 : -0.0125010098851659 ; 6 : 0.00328865844826621 ; 7 : -0.00441151119171934 ; 8 : -7.86344085887155e-05 ; 9 : -0.000263759546136583 ; 10 : 4.02706012758681e-11 ; Normalized w: 0 : 1 ; 1 : 0.0194979034611927 ; 2 : 1.24648759822547 ; 3 : 0.0497131025557711 ; 4 : 0.732918415161216 ; 5 : -0.136941702114008 ; 6 : 0.0882439661412266 ; 7 : -0.313186226090982 ; 8 : -0.0157896639303183 ; 9 : -0.15888748958586 ; 10 : 7.6713117208551e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 408 Number of False Discoveries by ASH at lfsr = 0.05: 2448 pihat0 estimated by ASH: 0.03139009 Unnormalized w: 0 : 1 ; 1 : 0.0157245248645571 ; 2 : 0.929021872834485 ; 3 : 0.033984050303064 ; 4 : 0.140368261784685 ; 5 : 0.0127121650881182 ; 6 : 3.86030488190746e-09 ; 7 : 0.00124250846025535 ; 8 : -4.78228642870409e-09 ; 9 : 7.91371830919831e-05 ; 10 : 8.56994353557394e-11 ; Normalized w: 0 : 1 ; 1 : 0.0157245248645571 ; 2 : 1.31383533230378 ; 3 : 0.0832435826355829 ; 4 : 0.687661234907779 ; 5 : 0.13925479146984 ; 6 : 1.03582849557833e-07 ; 7 : 0.0882093501845627 ; 8 : -9.60275493679947e-07 ; 9 : 0.0476718607480108 ; 10 : 1.63252363283959e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 331 Number of False Discoveries by ASH at lfsr = 0.05: 1822 pihat0 estimated by ASH: 0.04301549 Unnormalized w: 0 : 1 ; 1 : 0.00892124119206404 ; 2 : 0.759107789311292 ; 3 : -0.117082898525434 ; 4 : 0.111843761652649 ; 5 : -0.0297056700788412 ; 6 : 7.95126961962164e-11 ; 7 : -0.00211837385159652 ; 8 : -0.000229022454624607 ; 9 : -8.25473971461178e-05 ; 10 : 1.35581200265726e-12 ; Normalized w: 0 : 1 ; 1 : 0.00892124119206404 ; 2 : 1.07354053094709 ; 3 : -0.286793358993374 ; 4 : 0.547920293924901 ; 5 : -0.325409311759752 ; 6 : 2.13354952522835e-09 ; 7 : -0.150389624597725 ; 8 : -0.0459873439111496 ; 9 : -0.0497261573903446 ; 10 : 2.58274179618304e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 114 Number of False Discoveries by ASH at lfsr = 0.05: 1685 pihat0 estimated by ASH: 0.02583276 Unnormalized w: 0 : 1 ; 1 : 0.0480925696964731 ; 2 : 0.738515711602417 ; 3 : 0.00221250120053595 ; 4 : 0.0875509069264066 ; 5 : -0.00191476888655657 ; 6 : 1.55690130537233e-09 ; 7 : 0.00144844988545919 ; 8 : -7.20481946924742e-10 ; 9 : 0.000165048470111177 ; 10 : 1.38434287175444e-11 ; Normalized w: 0 : 1 ; 1 : 0.0480925696964731 ; 2 : 1.04441893537376 ; 3 : 0.00541949899660829 ; 4 : 0.428910096975195 ; 5 : -0.0209752422315216 ; 6 : 4.17760458368483e-08 ; 7 : 0.102829741010377 ; 8 : -1.44671626759531e-07 ; 9 : 0.0994244093154905 ; 10 : 2.6370914168932e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 79 Number of False Discoveries by ASH at lfsr = 0.05: 1814 pihat0 estimated by ASH: 0.01606004 Unnormalized w: 0 : 1 ; 1 : 0.036961161009979 ; 2 : 0.762234174397852 ; 3 : 0.0396536511894158 ; 4 : 0.0849620330092261 ; 5 : 0.00658028034188953 ; 6 : -0.00149261374799646 ; 7 : 0.000589489550662833 ; 8 : -2.63303502727629e-11 ; 9 : 4.91304899156167e-05 ; 10 : 1.39322722895517e-12 ; Normalized w: 0 : 1 ; 1 : 0.036961161009979 ; 2 : 1.0779619071377 ; 3 : 0.0971312118523761 ; 4 : 0.41622725676421 ; 5 : 0.072083359559214 ; 6 : -0.0400510296560499 ; 7 : 0.0418496065562984 ; 8 : -5.28709237388671e-09 ; 9 : 0.029595972237431 ; 10 : 2.6540155926857e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 35 Number of False Discoveries by ASH at lfsr = 0.05: 1137 pihat0 estimated by ASH: 0.04829662 Unnormalized w: 0 : 1 ; 1 : 0.0140143989353616 ; 2 : 0.597743966910777 ; 3 : 0.0535575884068385 ; 4 : 0.0630838568812921 ; 5 : 0.0166752029879321 ; 6 : -5.24874438717071e-09 ; 7 : 0.000478996844103069 ; 8 : -4.43928396179664e-11 ; 9 : -8.77921415623364e-05 ; 10 : 4.86920576666347e-12 ; Normalized w: 0 : 1 ; 1 : 0.0140143989353616 ; 2 : 0.845337624831916 ; 3 : 0.131188763450754 ; 4 : 0.309046520731854 ; 5 : 0.182667696549359 ; 6 : -1.4083859095481e-07 ; 7 : 0.0340054025468002 ; 8 : -8.91401144944578e-09 ; 9 : -0.0528855663520999 ; 10 : 9.27554942951506e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 28 Number of False Discoveries by ASH at lfsr = 0.05: 1653 pihat0 estimated by ASH: 0.02316832 Unnormalized w: 0 : 1 ; 1 : -0.052541093240518 ; 2 : 0.71740670301995 ; 3 : -0.0148451815829716 ; 4 : 0.0706308962096519 ; 5 : -0.0216927945431339 ; 6 : -0.00329645136528347 ; 7 : -0.00321089191984477 ; 8 : -5.51891940791841e-12 ; 9 : -4.485109559428e-05 ; 10 : 1.26313279205792e-12 ; Normalized w: 0 : 1 ; 1 : -0.052541093240518 ; 2 : 1.01456628914818 ; 3 : -0.0363631200172426 ; 4 : 0.346019311578251 ; 5 : -0.237632658131989 ; 6 : -0.0884530720475501 ; 7 : -0.227950713272539 ; 8 : -1.10819022198443e-09 ; 9 : -0.0270180855575947 ; 10 : 2.40619337325787e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 16 Number of False Discoveries by ASH at lfsr = 0.05: 1506 pihat0 estimated by ASH: 0.05110069 Unnormalized w: 0 : 1 ; 1 : -0.0298742128887614 ; 2 : 0.699187239719963 ; 3 : -0.0203438591846129 ; 4 : 0.0800846069265758 ; 5 : 0.00139184678102155 ; 6 : -3.32097337202773e-09 ; 7 : 0.00127034253818031 ; 8 : -1.18095009628928e-10 ; 9 : 0.000121048879283542 ; 10 : 6.3863496996739e-12 ; Normalized w: 0 : 1 ; 1 : -0.0298742128887614 ; 2 : 0.988800077050181 ; 3 : -0.0498320744013346 ; 4 : 0.39233284644294 ; 5 : 0.0152469175711291 ; 6 : -8.91110665358483e-08 ; 7 : 0.0901853736928798 ; 8 : -2.37132897335234e-08 ; 9 : 0.0729192661583677 ; 10 : 1.2165619025397e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 12 Number of False Discoveries by ASH at lfsr = 0.05: 795 pihat0 estimated by ASH: 0.04316169 Unnormalized w: 0 : 1 ; 1 : -0.0340541695971239 ; 2 : 0.513452746960379 ; 3 : 0.0332197000452204 ; 4 : 0.032903765181378 ; 5 : 0.0113186061652928 ; 6 : -0.00161876973099202 ; 7 : 0.000233268302218612 ; 8 : 1.07332741281119e-09 ; 9 : 2.68357174057194e-06 ; 10 : -1.00292555933494e-11 ; Normalized w: 0 : 1 ; 1 : -0.0340541695971239 ; 2 : 0.726131838389089 ; 3 : 0.0813713145191013 ; 4 : 0.161194870621464 ; 5 : 0.123989118324959 ; 6 : -0.0434361499010066 ; 7 : 0.016560406641522 ; 8 : 2.15522434003767e-07 ; 9 : 0.00161657078664457 ; 10 : -1.91051396172764e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 11 Number of False Discoveries by ASH at lfsr = 0.05: 1028 pihat0 estimated by ASH: 0.03156173 Unnormalized w: 0 : 1 ; 1 : 0.00890469934508206 ; 2 : 0.570145988689668 ; 3 : 0.0742781809986447 ; 4 : 0.049710222895347 ; 5 : 0.0105652157303946 ; 6 : -0.000780824169897197 ; 7 : -0.000868342123034908 ; 8 : -9.34567110080382e-10 ; 9 : -6.17440887286602e-05 ; 10 : 1.36250969299168e-10 ; Normalized w: 0 : 1 ; 1 : 0.00890469934508206 ; 2 : 0.806308189737545 ; 3 : 0.181943642468772 ; 4 : 0.243529362187236 ; 5 : 0.115736139608911 ; 6 : -0.0209517110683797 ; 7 : -0.0616461753468075 ; 8 : -1.87659586348254e-07 ; 9 : -0.0371943438581111 ; 10 : 2.59550050073108e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 9 Number of False Discoveries by ASH at lfsr = 0.05: 614 pihat0 estimated by ASH: 0.04794909 Unnormalized w: 0 : 1 ; 1 : -0.0124963683703915 ; 2 : 0.479455691782456 ; 3 : 0.0437902382837533 ; 4 : 0.0283590951436181 ; 5 : 0.00932976751648813 ; 6 : -0.00148770349123624 ; 7 : -0.000860378572827223 ; 8 : 3.94801560648696e-09 ; 9 : -9.53163745720882e-05 ; 10 : -9.98282366267257e-11 ; Normalized w: 0 : 1 ; 1 : -0.0124963683703915 ; 2 : 0.678052741875724 ; 3 : 0.107263739510085 ; 4 : 0.138930625337809 ; 5 : 0.10220248250119 ; 6 : -0.0399192736412158 ; 7 : -0.0610808193661828 ; 8 : 7.92755242099278e-07 ; 9 : -0.0574181283446029 ; 10 : -1.90166895314227e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 1307 pihat0 estimated by ASH: 0.05151585 Unnormalized w: 0 : 1 ; 1 : 0.0249866787261641 ; 2 : 0.622453028945155 ; 3 : 0.14478886016202 ; 4 : 0.0675724682587178 ; 5 : 0.020066114921205 ; 6 : -1.33026910243792e-08 ; 7 : -0.0024599148314936 ; 8 : -6.12782788990293e-10 ; 9 : -0.000245829910999426 ; 10 : 2.38424680814678e-11 ; Normalized w: 0 : 1 ; 1 : 0.0249866787261641 ; 2 : 0.880281515474451 ; 3 : 0.354658827836135 ; 4 : 0.331036135788542 ; 5 : 0.219813275676699 ; 6 : -3.56948656970259e-07 ; 7 : -0.174636628832954 ; 8 : -1.23045807479098e-07 ; 9 : -0.148086763098947 ; 10 : 4.54184936536026e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 689 pihat0 estimated by ASH: 0.04567195 Unnormalized w: 0 : 1 ; 1 : -0.0111641599125746 ; 2 : 0.483366099358236 ; 3 : 0.0430333304341389 ; 4 : 0.0252239744266155 ; 5 : 0.0053145247650554 ; 6 : -0.00149181259538353 ; 7 : -0.000500470553509336 ; 8 : 1.30187220486791e-09 ; 9 : -0.000109169976941762 ; 10 : 8.26950723192313e-12 ; Normalized w: 0 : 1 ; 1 : -0.0111641599125746 ; 2 : 0.683582893303798 ; 3 : 0.105409701496223 ; 4 : 0.12357173326044 ; 5 : 0.0582177019248137 ; 6 : -0.0400295324756155 ; 7 : -0.0355298846838391 ; 8 : 2.61413864032502e-07 ; 9 : -0.0657634721794694 ; 10 : 1.57529229125175e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 6 Number of False Discoveries by ASH at lfsr = 0.05: 1392 pihat0 estimated by ASH: 0.0308234 Unnormalized w: 0 : 1 ; 1 : 0.0396883802556293 ; 2 : 0.67106650481609 ; 3 : 0.0512893461267695 ; 4 : 0.0343206332660759 ; 5 : 0.0105514758544046 ; 6 : -0.00535610846077317 ; 7 : -0.0015066089219249 ; 8 : 2.09359032358976e-09 ; 9 : -0.000190699294743056 ; 10 : -1.35217763257903e-11 ; Normalized w: 0 : 1 ; 1 : 0.0396883802556293 ; 2 : 0.949031352365224 ; 3 : 0.125632727251578 ; 4 : 0.168136078302152 ; 5 : 0.11558562680857 ; 6 : -0.143719471357807 ; 7 : -0.106958623008449 ; 8 : 4.20389600564663e-07 ; 9 : -0.114876343439823 ; 10 : -2.57581853581548e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 4 Number of False Discoveries by ASH at lfsr = 0.05: 1149 pihat0 estimated by ASH: 0.02083846 Unnormalized w: 0 : 1 ; 1 : -0.00598719228952374 ; 2 : 0.580917336155386 ; 3 : -0.0165349746829778 ; 4 : 0.000950465157557428 ; 5 : -0.00671289660355908 ; 6 : -0.00617523768078916 ; 7 : -0.00125345735224704 ; 8 : 0.000270706421193476 ; 9 : -0.000154093702661098 ; 10 : -9.37294496814268e-11 ; Normalized w: 0 : 1 ; 1 : -0.00598719228952374 ; 2 : 0.821541175408597 ; 3 : -0.0405022508831337 ; 4 : 0.00465630930861943 ; 5 : -0.0735360979193824 ; 6 : -0.165699014777553 ; 7 : -0.0889866444072755 ; 8 : 0.0543574179692827 ; 9 : -0.0928253097771609 ; 10 : -1.78549066353598e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 508 pihat0 estimated by ASH: 0.03271534 Unnormalized w: 0 : 1 ; 1 : 0.00921377905881179 ; 2 : 0.44227129467301 ; 3 : 0.0372495054752143 ; 4 : 0.00273567450396983 ; 5 : 0.00394518920913478 ; 6 : -0.00222978584354968 ; 7 : -0.00106801649732043 ; 8 : -5.61894618061238e-11 ; 9 : -0.000106260001823252 ; 10 : 2.17619087094125e-11 ; Normalized w: 0 : 1 ; 1 : 0.00921377905881179 ; 2 : 0.625466063174878 ; 3 : 0.0912422815852832 ; 4 : 0.0134020132741351 ; 5 : 0.0432173824693818 ; 6 : -0.0598314326573256 ; 7 : -0.0758216496937715 ; 8 : -1.12827543853553e-08 ; 9 : -0.0640105170803662 ; 10 : 4.14551509194212e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 662 pihat0 estimated by ASH: 0.02787007 Unnormalized w: 0 : 1 ; 1 : 0.0351655201412852 ; 2 : 0.477980299062328 ; 3 : -0.0317266100935275 ; 4 : -0.00766843242627895 ; 5 : 0.0126420659517014 ; 6 : -0.00662466864866664 ; 7 : 0.00302793885516535 ; 8 : 1.98536054334988e-11 ; 9 : 7.04066901859213e-05 ; 10 : 5.64394017027393e-12 ; Normalized w: 0 : 1 ; 1 : 0.0351655201412852 ; 2 : 0.675966221481093 ; 3 : -0.0777140059973769 ; 4 : -0.0375674931427924 ; 5 : 0.138486893904298 ; 6 : -0.177758513121963 ; 7 : 0.214962334146066 ; 8 : 3.98657233170917e-09 ; 9 : 0.0424126535609731 ; 10 : 1.07513727156521e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 227 pihat0 estimated by ASH: 0.0531628 Unnormalized w: 0 : 1 ; 1 : 0.00154431090479713 ; 2 : 0.381972653262992 ; 3 : -0.0152915626373851 ; 4 : -0.0256118391191644 ; 5 : 0.00444072504619955 ; 6 : -0.00214165427285971 ; 7 : 0.00143888814188744 ; 8 : 0.00024743732335813 ; 9 : 0.000120611072083836 ; 10 : -9.14622234340302e-11 ; Normalized w: 0 : 1 ; 1 : 0.00154431090479713 ; 2 : 0.540190906700158 ; 3 : -0.0374565258314013 ; 4 : -0.125471874432412 ; 5 : 0.0486457055896333 ; 6 : -0.0574666144610064 ; 7 : 0.102150924556344 ; 8 : 0.04968502020632 ; 9 : 0.0726555331943753 ; 10 : -1.74230134245697e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 1340 pihat0 estimated by ASH: 0.03239883 Unnormalized w: 0 : 1 ; 1 : 0.0225205134556117 ; 2 : 0.641457207632186 ; 3 : 0.0533352583485684 ; 4 : 0.0364851668184028 ; 5 : 0.00612535217697635 ; 6 : -0.00444687379603166 ; 7 : -0.00232291022077059 ; 8 : 2.94218456475473e-10 ; 9 : -0.000245725498327179 ; 10 : -2.50902898268473e-12 ; Normalized w: 0 : 1 ; 1 : 0.0225205134556117 ; 2 : 0.907157482715412 ; 3 : 0.130644168253509 ; 4 : 0.178740083770822 ; 5 : 0.0670998711998665 ; 6 : -0.119322145143472 ; 7 : -0.164910266340676 ; 8 : 5.90785971843801e-08 ; 9 : -0.148023865404372 ; 10 : -4.77955203871478e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 193 pihat0 estimated by ASH: 0.0465218 Unnormalized w: 0 : 1 ; 1 : 0.0234366645597321 ; 2 : 0.351530157056736 ; 3 : 0.066259278805185 ; 4 : -0.00480114776628634 ; 5 : -0.00203790224616046 ; 6 : -0.000823976416513142 ; 7 : -0.00268310405895844 ; 8 : 1.90426127259697e-09 ; 9 : -0.000125066918170818 ; 10 : -3.02780954426344e-11 ; Normalized w: 0 : 1 ; 1 : 0.0234366645597321 ; 2 : 0.49713871569278 ; 3 : 0.162301423797512 ; 4 : -0.0235207244142095 ; 5 : -0.0223241006042506 ; 6 : -0.0221096073501608 ; 7 : -0.190481492149878 ; 8 : 3.8237262884611e-07 ; 9 : -0.0753397135742388 ; 10 : -5.76779837139999e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-12-20.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-100-1" class="section level3"> <h3><span class="math inline">\(\lambda = 100\)</span></h3> <pre class="r"><code>CorNullPlot("hostile", L, lambda = 100, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 639 Number of False Discoveries by ASH at lfsr = 0.05: 2300 pihat0 estimated by ASH: 0.04750946 Unnormalized w: 0 : 1 ; 1 : 0.0132006489023589 ; 2 : 0.752373085029163 ; 3 : 0.0203345251933944 ; 4 : 0.0867415022867811 ; 5 : -0.00760820428774983 ; 6 : -1.10494922428467e-09 ; 7 : -0.00294317971105688 ; 8 : -1.58067898541077e-11 ; 9 : -0.000164456475629658 ; 10 : 2.12731019116624e-13 ; Normalized w: 0 : 1 ; 1 : 0.0132006489023589 ; 2 : 1.06401622081273 ; 3 : 0.0498092108855858 ; 4 : 0.424944840250148 ; 5 : -0.0833437022101621 ; 6 : -2.96488989262341e-08 ; 7 : -0.208945031839351 ; 8 : -3.17397821250152e-09 ; 9 : -0.0990677946700876 ; 10 : 4.05240028366978e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 408 Number of False Discoveries by ASH at lfsr = 0.05: 2448 pihat0 estimated by ASH: 0.03139009 Unnormalized w: 0 : 1 ; 1 : 0.0105834739058566 ; 2 : 0.804961786327664 ; 3 : 0.0261787584314404 ; 4 : 0.0926865453395142 ; 5 : 0.00989805656833703 ; 6 : -2.5354523725189e-09 ; 7 : 0.00095688222754701 ; 8 : 2.04811826297778e-11 ; 9 : 7.72597502545557e-05 ; 10 : -8.7238564600081e-13 ; Normalized w: 0 : 1 ; 1 : 0.0105834739058566 ; 2 : 1.13838787541666 ; 3 : 0.0641246002566118 ; 4 : 0.454069484206296 ; 5 : 0.108427777158807 ; 6 : -6.80333263039845e-08 ; 7 : 0.0679318992143783 ; 8 : 4.11258883259499e-09 ; 9 : 0.0465409041825547 ; 10 : -1.66184313599561e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 331 Number of False Discoveries by ASH at lfsr = 0.05: 1822 pihat0 estimated by ASH: 0.04301549 Unnormalized w: 0 : 1 ; 1 : 0.0320131581939377 ; 2 : 0.649515689894355 ; 3 : -0.0900465711396185 ; 4 : 0.0650229035742284 ; 5 : -0.0206964966588597 ; 6 : -2.21942942133303e-10 ; 7 : -0.00135553600458204 ; 8 : -3.74724715625219e-12 ; 9 : -8.11909005353444e-05 ; 10 : -2.22930395954244e-13 ; Normalized w: 0 : 1 ; 1 : 0.0320131581939377 ; 2 : 0.918553897622715 ; 3 : -0.220568152379291 ; 4 : 0.318545870702104 ; 5 : -0.226718761627755 ; 6 : -5.95535406883642e-09 ; 7 : -0.0962335098236571 ; 8 : -7.52441257243127e-10 ; 9 : -0.0489090103172832 ; 10 : -4.24669238907905e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 114 Number of False Discoveries by ASH at lfsr = 0.05: 1685 pihat0 estimated by ASH: 0.02583276 Unnormalized w: 0 : 1 ; 1 : 0.0478741427101273 ; 2 : 0.636744066444071 ; 3 : 0.00280039305560423 ; 4 : 0.0471915925960114 ; 5 : -0.00175976181128063 ; 6 : -1.19238687936139e-10 ; 7 : 0.0011904959700241 ; 8 : 1.02063407037529e-12 ; 9 : 0.000131391532916318 ; 10 : -3.43621756805811e-14 ; Normalized w: 0 : 1 ; 1 : 0.0478741427101273 ; 2 : 0.900492094525801 ; 3 : 0.00685953406546381 ; 4 : 0.231190644019065 ; 5 : -0.019277224797491 ; 6 : -3.19950974127709e-09 ; 7 : 0.0845168296814539 ; 8 : 2.04941694816425e-10 ; 9 : 0.079149631259606 ; 10 : -6.5457915377709e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 79 Number of False Discoveries by ASH at lfsr = 0.05: 1814 pihat0 estimated by ASH: 0.01606004 Unnormalized w: 0 : 1 ; 1 : 0.0295010267165937 ; 2 : 0.659217346324276 ; 3 : 0.0316891852491315 ; 4 : 0.0493837441677906 ; 5 : 0.00471433747948774 ; 6 : -2.37451148091981e-10 ; 7 : 0.000401980706948216 ; 8 : 1.94606595925071e-12 ; 9 : 3.81187051320671e-05 ; 10 : -1.35441607673461e-13 ; Normalized w: 0 : 1 ; 1 : 0.0295010267165937 ; 2 : 0.932274111723392 ; 3 : 0.0776223342249036 ; 4 : 0.241929949598464 ; 5 : 0.0516429796241497 ; 6 : -6.37148290162847e-09 ; 7 : 0.0285377992028692 ; 8 : 3.90766943304903e-10 ; 9 : 0.0229625257300127 ; 10 : -2.58008263973824e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 35 Number of False Discoveries by ASH at lfsr = 0.05: 1137 pihat0 estimated by ASH: 0.04829662 Unnormalized w: 0 : 1 ; 1 : 0.00424558401539101 ; 2 : 0.511849996157535 ; 3 : 0.0374277614247891 ; 4 : 0.0281204777136469 ; 5 : 0.0113184645140339 ; 6 : -2.90301822299753e-09 ; 7 : 5.69592362256861e-05 ; 8 : 4.37033454229306e-11 ; 9 : -8.45744624616698e-05 ; 10 : -7.98561492042503e-13 ; Normalized w: 0 : 1 ; 1 : 0.00424558401539101 ; 2 : 0.723865206466603 ; 3 : 0.0916789177053568 ; 4 : 0.137761643443482 ; 5 : 0.123987566613162 ; 6 : -7.78961530385176e-08 ; 7 : 0.00404370463074693 ; 8 : 8.77556211388247e-09 ; 9 : -0.0509472518452458 ; 10 : -1.52121248246675e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 28 Number of False Discoveries by ASH at lfsr = 0.05: 1653 pihat0 estimated by ASH: 0.02316832 Unnormalized w: 0 : 1 ; 1 : -0.0579073929769914 ; 2 : 0.624297610453676 ; 3 : -0.0095361725642879 ; 4 : 0.0443091090631803 ; 5 : -0.0181144765657234 ; 6 : -5.04721944409982e-11 ; 7 : -0.00249283417116588 ; 8 : 6.12226107696798e-13 ; 9 : -8.99258314026113e-07 ; 10 : -1.16057368162252e-14 ; Normalized w: 0 : 1 ; 1 : -0.0579073929769914 ; 2 : 0.882890147660704 ; 3 : -0.0233587568816336 ; 4 : 0.217069416324243 ; 5 : -0.198434148648908 ; 6 : -1.35431109292391e-09 ; 7 : -0.176973670111852 ; 8 : 1.2293402676251e-10 ; 9 : -0.000541708909109335 ; 10 : -2.21082432461269e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 16 Number of False Discoveries by ASH at lfsr = 0.05: 1506 pihat0 estimated by ASH: 0.05110069 Unnormalized w: 0 : 1 ; 1 : -0.0255909251559379 ; 2 : 0.600752193190829 ; 3 : -0.0163386802555427 ; 4 : 0.0405728780387057 ; 5 : 0.00103539670420155 ; 6 : -2.44797260617011e-09 ; 7 : 0.000832340077074178 ; 8 : 2.22226746125963e-11 ; 9 : 8.01163387009444e-05 ; 10 : -4.91281792152021e-13 ; Normalized w: 0 : 1 ; 1 : -0.0255909251559379 ; 2 : 0.849591899235853 ; 3 : -0.0400214296965659 ; 4 : 0.198765697182005 ; 5 : 0.0113422026171538 ; 6 : -6.56859978534442e-08 ; 7 : 0.0590902836317055 ; 8 : 4.4622776474479e-09 ; 9 : 0.0482616994056085 ; 10 : -9.35862800895627e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 12 Number of False Discoveries by ASH at lfsr = 0.05: 795 pihat0 estimated by ASH: 0.04316169 Unnormalized w: 0 : 1 ; 1 : -0.0401783346044442 ; 2 : 0.442275121559582 ; 3 : 0.0256458281127914 ; 4 : 0.00801944125993727 ; 5 : 0.00883988432919291 ; 6 : -3.95773494187874e-09 ; 7 : 0.000148824574319465 ; 8 : 6.11514127702424e-11 ; 9 : 2.03215738949129e-05 ; 10 : -1.26491688747154e-12 ; Normalized w: 0 : 1 ; 1 : -0.0401783346044442 ; 2 : 0.62547147520977 ; 3 : 0.0628191929074629 ; 4 : 0.0392870782181371 ; 5 : 0.0968360810567076 ; 6 : -1.06197172403604e-07 ; 7 : 0.0105654966643175 ; 8 : 1.22791062314273e-08 ; 9 : 0.012241618958975 ; 10 : -2.40959196965922e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 11 Number of False Discoveries by ASH at lfsr = 0.05: 1028 pihat0 estimated by ASH: 0.03156173 Unnormalized w: 0 : 1 ; 1 : -0.00713289775443022 ; 2 : 0.490130637935728 ; 3 : 0.0579248234639622 ; 4 : 0.018975962213149 ; 5 : 0.00726873754490585 ; 6 : -7.24970694698185e-09 ; 7 : -0.000689894217038701 ; 8 : 7.44854402225804e-11 ; 9 : -1.98960670986822e-05 ; 10 : -7.81088085699679e-13 ; Normalized w: 0 : 1 ; 1 : -0.00713289775443022 ; 2 : 0.693149395503284 ; 3 : 0.141886260927502 ; 4 : 0.0929628496010994 ; 5 : 0.0796250303585931 ; 6 : -1.94530050604847e-07 ; 7 : -0.0489776307588 ; 8 : 1.49565576943263e-08 ; 9 : -0.0119852956992292 ; 10 : -1.48792667529374e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 9 Number of False Discoveries by ASH at lfsr = 0.05: 614 pihat0 estimated by ASH: 0.04794909 Unnormalized w: 0 : 1 ; 1 : -0.0216291449788825 ; 2 : 0.412382435293265 ; 3 : 0.0328952487332636 ; 4 : 0.00476671911085713 ; 5 : 0.00692737740690498 ; 6 : -4.67825631219419e-09 ; 7 : -0.000695071135321422 ; 8 : 8.4765279556321e-11 ; 9 : -5.62605303714553e-05 ; 10 : -2.18482832828739e-12 ; Normalized w: 0 : 1 ; 1 : -0.0216291449788825 ; 2 : 0.583196832876181 ; 3 : 0.0805765743584305 ; 4 : 0.0233520591375462 ; 5 : 0.0758856174022701 ; 6 : -1.25530789562804e-07 ; 7 : -0.049345155497894 ; 8 : 1.70207330502624e-08 ; 9 : -0.0338910745200501 ; 10 : -4.16196893809255e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 1307 pihat0 estimated by ASH: 0.05151585 Unnormalized w: 0 : 1 ; 1 : -0.00576684163508081 ; 2 : 0.533396059333378 ; 3 : 0.112031445464562 ; 4 : 0.0313056394050992 ; 5 : 0.013527135945386 ; 6 : -1.943881958565e-09 ; 7 : -0.00189092404907672 ; 8 : 2.15307400468982e-11 ; 9 : -0.000133799657639083 ; 10 : -3.69261244798069e-13 ; Normalized w: 0 : 1 ; 1 : -0.00576684163508081 ; 2 : 0.754335941225627 ; 3 : 0.274419876534617 ; 4 : 0.153365685228119 ; 5 : 0.148182349914538 ; 6 : -5.21598263950411e-08 ; 7 : -0.134242290457436 ; 8 : 4.32333828934467e-09 ; 9 : -0.0806002740796074 ; 10 : -7.0342086423588e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 7 Number of False Discoveries by ASH at lfsr = 0.05: 689 pihat0 estimated by ASH: 0.04567195 Unnormalized w: 0 : 1 ; 1 : -0.0196084763181005 ; 2 : 0.41744821858852 ; 3 : 0.033978148075886 ; 4 : 0.00159291246628547 ; 5 : 0.00320468943817534 ; 6 : -7.15177316371031e-09 ; 7 : -0.000437503823423119 ; 8 : 1.05264756576142e-10 ; 9 : -8.59829439510085e-05 ; 10 : -1.91203575190933e-12 ; Normalized w: 0 : 1 ; 1 : -0.0196084763181005 ; 2 : 0.590360932316373 ; 3 : 0.0832291251906506 ; 4 : 0.00780364549463543 ; 5 : 0.0351056139017439 ; 6 : -1.9190221144458e-07 ; 7 : -0.0310596902973876 ; 8 : 2.11369953672236e-08 ; 9 : -0.0517957143606207 ; 10 : -3.64231519013986e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 6 Number of False Discoveries by ASH at lfsr = 0.05: 1392 pihat0 estimated by ASH: 0.0308234 Unnormalized w: 0 : 1 ; 1 : 0.0355436726283037 ; 2 : 0.585233420234378 ; 3 : 0.0476532741151539 ; 4 : 0.0178494867394756 ; 5 : 0.0122996901187348 ; 6 : -2.66739447471334e-09 ; 7 : -0.000751737424430662 ; 8 : 2.77298665063982e-11 ; 9 : -0.00013791935465543 ; 10 : -7.00702380706679e-13 ; Normalized w: 0 : 1 ; 1 : 0.0355436726283037 ; 2 : 0.82764504004945 ; 3 : 0.116726206155104 ; 4 : 0.0874442693645797 ; 5 : 0.134736354567089 ; 6 : -7.15737044191964e-08 ; 7 : -0.0533680629464834 ; 8 : 5.56811300328707e-09 ; 9 : -0.0830819598664138 ; 10 : -1.33479665454296e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 4 Number of False Discoveries by ASH at lfsr = 0.05: 1149 pihat0 estimated by ASH: 0.02083846 Unnormalized w: 0 : 1 ; 1 : -0.00969769073359043 ; 2 : 0.514996324871894 ; 3 : -0.0282187966040121 ; 4 : 9.64676465435185e-08 ; 5 : -0.0120747164945973 ; 6 : -2.24791804163654e-08 ; 7 : -0.00173122912010175 ; 8 : 1.92088522400817e-10 ; 9 : -0.000142282975799265 ; 10 : -3.47438547259262e-12 ; Normalized w: 0 : 1 ; 1 : -0.00969769073359043 ; 2 : 0.728314787206133 ; 3 : -0.0691216528352123 ; 4 : 4.72593021437563e-07 ; 5 : -0.132271891991413 ; 6 : -6.031797058737e-07 ; 7 : -0.122905075168167 ; 8 : 3.8571069179702e-08 ; 9 : -0.0857105843814436 ; 10 : -6.6184991418641e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 508 pihat0 estimated by ASH: 0.03271534 Unnormalized w: 0 : 1 ; 1 : 0.00654401496867742 ; 2 : 0.40702927663415 ; 3 : 0.0352668942739153 ; 4 : 2.73924919551974e-09 ; 5 : 0.0044439418035202 ; 6 : -2.34446864226924e-10 ; 7 : -0.000744264268223872 ; 8 : 3.409573903626e-12 ; 9 : -8.07206253491806e-05 ; 10 : -3.65500557341514e-14 ; Normalized w: 0 : 1 ; 1 : 0.00654401496867742 ; 2 : 0.575626323298925 ; 3 : 0.0863858957837742 ; 4 : 1.34195256147054e-08 ; 5 : 0.0486809434005641 ; 6 : -6.29086950627678e-09 ; 7 : -0.0528375214862722 ; 8 : 6.8463700624263e-10 ; 9 : -0.0486257187934747 ; 10 : -6.96256976722428e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 662 pihat0 estimated by ASH: 0.02787007 Unnormalized w: 0 : 1 ; 1 : 0.0453588752881293 ; 2 : 0.438090234532152 ; 3 : -0.0291189579394965 ; 4 : 2.86793713120655e-09 ; 5 : 0.0110860517404839 ; 6 : -5.70878155827704e-10 ; 7 : 0.00236930640711469 ; 8 : 8.82670765931082e-12 ; 9 : 2.12285880554833e-05 ; 10 : -2.14657496309032e-13 ; Normalized w: 0 : 1 ; 1 : 0.0453588752881293 ; 2 : 0.619553151218579 ; 3 : -0.0713265887933314 ; 4 : 1.40499651716749e-08 ; 5 : 0.121441612238648 ; 6 : -1.53182683596056e-08 ; 7 : 0.168204068821195 ; 8 : 1.7723888314674e-09 ; 9 : 0.0127879999529627 ; 10 : -4.08909853648414e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 227 pihat0 estimated by ASH: 0.0531628 Unnormalized w: 0 : 1 ; 1 : -0.00364409182611866 ; 2 : 0.389125880616772 ; 3 : -0.0255220177701119 ; 4 : -4.63675182385451e-07 ; 5 : -1.39719095146074e-05 ; 6 : -1.263904769272e-09 ; 7 : 0.000725526774932154 ; 8 : 9.04561852541172e-11 ; 9 : 8.39572550250558e-05 ; 10 : -1.78894463147996e-12 ; Normalized w: 0 : 1 ; 1 : -0.00364409182611866 ; 2 : 0.550307097838612 ; 3 : -0.0625159207430191 ; 4 : -2.27153520647256e-06 ; 5 : -0.00015305460025143 ; 6 : -3.39141237741406e-08 ; 7 : 0.051507291423283 ; 8 : 1.81634578451714e-08 ; 9 : 0.0505754490362338 ; 10 : -3.40783387499525e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 1340 pihat0 estimated by ASH: 0.03239883 Unnormalized w: 0 : 1 ; 1 : 0.0149991776855961 ; 2 : 0.559603231383086 ; 3 : 0.0465049266719185 ; 4 : 0.0184397682568843 ; 5 : 0.00703650419080853 ; 6 : -1.03776921070471e-09 ; 7 : -0.00149386108442593 ; 8 : 1.3106876747849e-11 ; 9 : -0.000178408010293136 ; 10 : -3.29469209420909e-13 ; Normalized w: 0 : 1 ; 1 : 0.0149991776855961 ; 2 : 0.791398479369769 ; 3 : 0.113913340871748 ; 4 : 0.0903360464090738 ; 5 : 0.0770810414257094 ; 6 : -2.78462700011043e-08 ; 7 : -0.106053616323978 ; 8 : 2.63183996343221e-09 ; 9 : -0.107472132450538 ; 10 : -6.27619386802165e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 193 pihat0 estimated by ASH: 0.0465218 Unnormalized w: 0 : 1 ; 1 : 0.0226849154498927 ; 2 : 0.335107595160482 ; 3 : 0.0658274203844355 ; 4 : -1.28338913347439e-08 ; 5 : -0.00247141282053187 ; 6 : -2.49427997598805e-10 ; 7 : -0.00298977044563244 ; 8 : 1.268457383768e-11 ; 9 : -0.000163497363465059 ; 10 : -4.22926284937891e-13 ; Normalized w: 0 : 1 ; 1 : 0.0226849154498927 ; 2 : 0.473913705930186 ; 3 : 0.161243591025551 ; 4 : -6.28729703688982e-08 ; 5 : -0.0270729710142555 ; 6 : -6.69285549747098e-09 ; 7 : -0.212252645874178 ; 8 : 2.54704221206563e-09 ; 9 : -0.0984900300875476 ; 10 : -8.05649596457834e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-13-20.png" width="672" style="display: block; margin: auto;" /></p> </div> </div> <div id="friendly" class="section level2"> <h2>Friendly</h2> <p>A good part of “friendly” data sets are deflated.</p> <div id="no-regularization-lambda-0-2" class="section level3"> <h3>No regularization: <span class="math inline">\(\lambda = 0\)</span></h3> <pre class="r"><code>CorNullPlot("friendly", L, lambda = 0, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 137264954.214438 ; 2 : -722937240.714833 ; 3 : 418842016.840356 ; 4 : -1016772968.34235 ; 5 : 240045934.151314 ; 6 : -374946652.070722 ; 7 : 41386034.8214318 ; 8 : -47114090.7012788 ; 9 : 2040876.13279973 ; 10 : -1807482.83610991 ; Normalized w: 0 : 1 ; 1 : 137264954.214438 ; 2 : -1022387650.5635 ; 3 : 1025949224.09707 ; 4 : -4981149913.38756 ; 5 : 2629571459.44149 ; 6 : -10060874423.5932 ; 7 : 2938117006.91675 ; 8 : -9460434330.30259 ; 9 : 1229414025.18311 ; 10 : -3443148060.02248 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -106261819.01034 ; 2 : -1150357596.48619 ; 3 : -232331281.30916 ; 4 : -1340627938.14957 ; 5 : -112068963.548569 ; 6 : -456263013.117482 ; 7 : -17279425.242415 ; 8 : -54979962.6558813 ; 9 : -796936.796482575 ; 10 : -2072478.27497457 ; Normalized w: 0 : 1 ; 1 : -106261819.01034 ; 2 : -1626851314.52968 ; 3 : -569093090.49446 ; 4 : -6567708766.77187 ; 5 : -1227653986.63551 ; 6 : -12242821355.3948 ; 7 : -1226717500.08279 ; 8 : -11039888883.4829 ; 9 : -480070916.129586 ; 10 : -3947948721.48013 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -419300836.933388 ; 2 : -1694585535.52468 ; 3 : -810682683.439507 ; 4 : -1975460074.67748 ; 5 : -352299236.564591 ; 6 : -662240105.602199 ; 7 : -48370939.631651 ; 8 : -77601017.7932235 ; 9 : -1837301.55401029 ; 10 : -2799846.58349772 ; Normalized w: 0 : 1 ; 1 : -419300836.933388 ; 2 : -2396505846.94028 ; 3 : -1985758917.73701 ; 4 : -9677738380.40037 ; 5 : -3859244777.16551 ; 6 : -17769766722.6379 ; 7 : -3433996056.53211 ; 8 : -15582160705.4279 ; 9 : -1106781672.18913 ; 10 : -5333542393.72954 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -89489789.7327784 ; 2 : -726111664.311445 ; 3 : -272260748.650809 ; 4 : -1053172284.98039 ; 5 : -156103245.723899 ; 6 : -394990362.858399 ; 7 : -26803318.7269033 ; 8 : -50144491.564265 ; 9 : -1312898.58614155 ; 10 : -1939839.37563693 ; Normalized w: 0 : 1 ; 1 : -89489789.7327784 ; 2 : -1026876963.46655 ; 3 : -666899911.182626 ; 4 : -5159469418.88598 ; 5 : -1710025379.65503 ; 6 : -10598703621.7043 ; 7 : -1902846864.48249 ; 8 : -10068933994.247 ; 9 : -790883831.460775 ; 10 : -3695279451.36922 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 112889894.796798 ; 2 : -742338300.549163 ; 3 : 348258998.62458 ; 4 : -1034780345.77285 ; 5 : 201205933.841486 ; 6 : -381144424.471816 ; 7 : 34878380.5459064 ; 8 : -48017141.8842725 ; 9 : 1727489.57462506 ; 10 : -1850641.97462528 ; Normalized w: 0 : 1 ; 1 : 112889894.796798 ; 2 : -1049824892.50562 ; 3 : 853056844.962849 ; 4 : -5069367686.00843 ; 5 : 2204100573.37748 ; 6 : -10227178108.3682 ; 7 : 2476119384.1787 ; 8 : -9641765568.71662 ; 9 : 1040631460.80706 ; 10 : -3525363670.08672 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0470784370671212 ; 2 : -0.522631688675864 ; 3 : -0.0953426864633527 ; 4 : -0.740438283008238 ; 5 : -0.0559007315179676 ; 6 : -0.323435338420103 ; 7 : -0.0120562733702888 ; 8 : -0.0484360784107513 ; 9 : -0.000623238470056528 ; 10 : -0.00232871526180744 ; Normalized w: 0 : 1 ; 1 : -0.0470784370671212 ; 2 : -0.73911282225136 ; 3 : -0.233540932541375 ; 4 : -3.62739195878534 ; 5 : -0.612361832668617 ; 6 : -8.67868083639599 ; 7 : -0.855910501745851 ; 8 : -9.72588735560298 ; 9 : -0.375435874724077 ; 10 : -4.43606504905667 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00193985466749854 ; 2 : -0.0459043485242219 ; 3 : -0.0122824286035569 ; 4 : -0.00607306381602981 ; 5 : 0.00351725498554623 ; 6 : 0.0013871020433342 ; 7 : 0.000277482321742012 ; 8 : 1.13547480823551e-05 ; 9 : 6.74311181102265e-05 ; 10 : -3.01075670970948e-06 ; Normalized w: 0 : 1 ; 1 : -0.00193985466749854 ; 2 : -0.0649185522548561 ; 3 : -0.0300856828808792 ; 4 : -0.0297518150492654 ; 5 : 0.0385295979216235 ; 6 : 0.0372198535274896 ; 7 : 0.0196992906459055 ; 8 : 0.00228001531964903 ; 9 : 0.0406201831684736 ; 10 : -0.00573531372864746 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 2.02099465369633 ; 2 : -12.7500510381693 ; 3 : 6.38103409252514 ; 4 : -19.5151088875592 ; 5 : 3.76180647511564 ; 6 : -7.60904274513008 ; 7 : 0.668035566785343 ; 8 : -1.00409684615153 ; 9 : 0.03413427725234 ; 10 : -0.0406102718894945 ; Normalized w: 0 : 1 ; 1 : 2.02099465369633 ; 2 : -18.0312950991282 ; 3 : 15.6302775579901 ; 4 : -95.604118098746 ; 5 : 41.2085252677967 ; 6 : -204.17204186175 ; 7 : 47.4258205326031 ; 8 : -201.621046546541 ; 9 : 20.5623254243983 ; 10 : -77.3601696679102 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00956223065055579 ; 2 : -0.139729871584823 ; 3 : -0.0126291983086343 ; 4 : -0.0264973264835549 ; 5 : -0.0135840230877693 ; 6 : -0.0171736274688293 ; 7 : -0.00307870144367361 ; 8 : -0.00289615242500924 ; 9 : -0.000290457029780478 ; 10 : -0.000167919884508643 ; Normalized w: 0 : 1 ; 1 : 0.00956223065055579 ; 2 : -0.197607879463907 ; 3 : -0.0309350917165744 ; 4 : -0.12980985886529 ; 5 : -0.148805517336844 ; 6 : -0.46081678128672 ; 7 : -0.218566120429404 ; 8 : -0.58154279154119 ; 9 : -0.174969926095063 ; 10 : -0.319877463306641 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -594780833.462949 ; 2 : -1270269526.86431 ; 3 : -1419762879.07984 ; 4 : -1225019415.59396 ; 5 : -679108078.765335 ; 6 : -325170028.421899 ; 7 : -98308952.1848364 ; 8 : -27646118.6308513 ; 9 : -3938191.62464207 ; 10 : -573780.43118111 ; Normalized w: 0 : 1 ; 1 : -594780833.462949 ; 2 : -1796432392.76076 ; 3 : -3477694609.49039 ; 4 : -6001344986.41527 ; 5 : -7439256274.47538 ; 6 : -8725227453.56286 ; 7 : -6979243254.22101 ; 8 : -5551296563.34054 ; 9 : -2372347806.6019 ; 10 : -1093017836.20365 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 541173520.168442 ; 2 : -1829704125.01795 ; 3 : 1176846048.20616 ; 4 : -2016580491.23649 ; 5 : 536195866.719198 ; 6 : -626478339.28782 ; 7 : 74728716.7247109 ; 8 : -66565470.6376099 ; 9 : 2831468.61953214 ; 10 : -2084985.52075391 ; Normalized w: 0 : 1 ; 1 : 541173520.168442 ; 2 : -2587592388.73039 ; 3 : 2882672323.91591 ; 4 : -9879186457.56089 ; 5 : 5873731428.86276 ; 6 : -16810177836.9449 ; 7 : 5305212602.78448 ; 8 : -13366240423.1798 ; 9 : 1705663159.45067 ; 10 : -3971774286.06145 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -56432232.5590155 ; 2 : -942778323.786737 ; 3 : -117054726.547689 ; 4 : -996286639.780001 ; 5 : -54991463.4341151 ; 6 : -316578729.109756 ; 7 : -8028402.56625314 ; 8 : -35258958.3436016 ; 9 : -342254.887985098 ; 10 : -1218041.30050927 ; Normalized w: 0 : 1 ; 1 : -56432232.5590155 ; 2 : -1333289891.81058 ; 3 : -286724352.022854 ; 4 : -4880787810.02606 ; 5 : -602401299.861707 ; 6 : -8494698702.23887 ; 7 : -569960041.353543 ; 8 : -7079942645.59718 ; 9 : -206172708.237381 ; 10 : -2320296744.78231 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -1.95677009214905 ; 2 : -12.2569463569483 ; 3 : -6.0748809266641 ; 4 : -18.9489453242006 ; 5 : -3.56745776349149 ; 6 : -7.40452267280642 ; 7 : -0.632340146447155 ; 8 : -0.979899114651218 ; 9 : -0.0321248697380335 ; 10 : -0.0397131144151632 ; Normalized w: 0 : 1 ; 1 : -1.95677009214905 ; 2 : -17.3339397712759 ; 3 : -14.8803585184929 ; 4 : -92.8304944163773 ; 5 : -39.0795418002244 ; 6 : -198.684192448003 ; 7 : -44.8916970772592 ; 8 : -196.762180623553 ; 9 : -19.3518679445473 ; 10 : -75.6511376618707 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 7.92438556157571 ; 2 : -16.5970527053141 ; 3 : 24.2623695599727 ; 4 : -23.6100003489604 ; 5 : 14.0732466851824 ; 6 : -8.4629472072654 ; 7 : 2.45683144457811 ; 8 : -1.01755591322698 ; 9 : 0.12335441226633 ; 10 : -0.036891785992626 ; Normalized w: 0 : 1 ; 1 : 7.92438556157571 ; 2 : -23.4717770312763 ; 3 : 59.4304253727679 ; 4 : -115.664907363771 ; 5 : 154.164693336184 ; 6 : -227.084702945249 ; 7 : 174.417730077024 ; 8 : -204.323605766494 ; 9 : 74.308108204687 ; 10 : -70.2766736334032 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 2074419142.47283 ; 2 : -3573068586.86138 ; 3 : 4229152806.46 ; 4 : -2931614091.00329 ; 5 : 1490639188.00118 ; 6 : -493475675.41199 ; 7 : 116534592.449922 ; 8 : -3852453.55778051 ; 9 : -642084.639127706 ; 10 : 1572783.00239395 ; Normalized w: 0 : 1 ; 1 : 2074419142.47283 ; 2 : -5053082054.82863 ; 3 : 10359266420.0865 ; 4 : -14361917291.4224 ; 5 : 16329134167.3886 ; 6 : -13241341865.566 ; 7 : 8273135357.09687 ; 8 : -773566535.009745 ; 9 : -386788716.87099 ; 10 : 2996058737.23481 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 618987692.527178 ; 2 : -1801617642.29182 ; 3 : 1634174783.76893 ; 4 : -2191247482.97095 ; 5 : 887369121.590212 ; 6 : -748173277.136419 ; 7 : 147704383.115058 ; 8 : -88172740.9916949 ; 9 : 7183741.46857466 ; 10 : -3199467.88204137 ; Normalized w: 0 : 1 ; 1 : 618987692.527178 ; 2 : -2547872103.93973 ; 3 : 4002894370.75692 ; 4 : -10734876466.8736 ; 5 : 9720641694.57007 ; 6 : -20075595679.5099 ; 7 : 10485970977.8663 ; 8 : -17704945876.2465 ; 9 : 4327451515.95236 ; 10 : -6094797367.40641 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00984700926515223 ; 2 : -0.14656240112422 ; 3 : -0.0118379136012733 ; 4 : 0.010345781454132 ; 5 : -0.0011892934303944 ; 6 : -0.000753308229453712 ; 7 : -0.000550648736682494 ; 8 : -0.000132519405015875 ; 9 : -4.83894388687729e-05 ; 10 : -2.69726822353638e-06 ; Normalized w: 0 : 1 ; 1 : 0.00984700926515223 ; 2 : -0.207270535403837 ; 3 : -0.0289968479422725 ; 4 : 0.0506837711059456 ; 5 : -0.0130280567863943 ; 6 : -0.0202133809088221 ; 7 : -0.0390921823041198 ; 8 : -0.0266096853400468 ; 9 : -0.0291495666296999 ; 10 : -0.00513813667587426 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -1014237.02898209 ; 2 : -597951917.012121 ; 3 : -2677628.90712859 ; 4 : -672071077.344696 ; 5 : -927136.046849423 ; 6 : -223161520.271774 ; 7 : -135927.093818087 ; 8 : -26093284.1988066 ; 9 : -6567.46435896308 ; 10 : -950757.022531773 ; Normalized w: 0 : 1 ; 1 : -1014237.02898209 ; 2 : -845631710.685534 ; 3 : -6558824.54299121 ; 4 : -3292462420.75415 ; 5 : -10156266.5347119 ; 6 : -5988051951.4786 ; 7 : -9649866.380552 ; 8 : -5239489884.03232 ; 9 : -3956209.13147879 ; 10 : -1811135979.98446 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0403717474792552 ; 2 : -0.229979607667662 ; 3 : 0.0189204963837437 ; 4 : -0.0173306848000264 ; 5 : 0.0141130226810881 ; 6 : -0.0231338566722466 ; 7 : 0.00350234700086261 ; 8 : -0.00330846703656365 ; 9 : 0.000289669799494303 ; 10 : -0.000209805713849822 ; Normalized w: 0 : 1 ; 1 : -0.0403717474792552 ; 2 : -0.32524028023285 ; 3 : 0.0463455618203464 ; 4 : -0.0849026693061461 ; 5 : 0.15460041754028 ; 6 : -0.620746513210565 ; 7 : 0.248641971422434 ; 8 : -0.66433490846363 ; 9 : 0.174495702334337 ; 10 : -0.399667494590647 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 254386788.899495 ; 2 : -971207864.341701 ; 3 : 766962554.079245 ; 4 : -1422015137.03137 ; 5 : 436058921.203189 ; 6 : -527639757.022056 ; 7 : 74048282.6100759 ; 8 : -65810466.7577094 ; 9 : 3571375.30780089 ; 10 : -2484460.4768662 ; Normalized w: 0 : 1 ; 1 : 254386788.899495 ; 2 : -1373495333.63544 ; 3 : 1878666909.3159 ; 4 : -6966422984.4815 ; 5 : 4776786150.88709 ; 6 : -14158060371.9935 ; 7 : 5256906572.6726 ; 8 : -13214636847.294 ; 9 : 2151379411.04724 ; 10 : -4732750486.04897 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-20.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 4.57639504918881 ; 2 : -57.5764820561853 ; 3 : 13.8021136775458 ; 4 : -87.1897901256237 ; 5 : 7.92280745858439 ; 6 : -33.4062693534841 ; 7 : 1.36236273420077 ; 8 : -4.30800695157544 ; 9 : 0.0667879534755144 ; 10 : -0.168853283481368 ; Normalized w: 0 : 1 ; 1 : 4.57639504918881 ; 2 : -81.4254417975884 ; 3 : 33.8081358818758 ; 4 : -427.140993176266 ; 5 : 86.790007276737 ; 6 : -896.3842697887 ; 7 : 96.7181595486419 ; 8 : -865.040930499382 ; 9 : 40.2327438674259 ; 10 : -321.655533226841 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-21.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -843569484.171597 ; 2 : -2345053461.51224 ; 3 : -2329106746.43836 ; 4 : -2884547641.49376 ; 5 : -1293771901.31835 ; 6 : -978697186.533303 ; 7 : -219384288.369108 ; 8 : -114612626.09425 ; 9 : -10793693.7396976 ; 10 : -4120637.71361765 ; Normalized w: 0 : 1 ; 1 : -843569484.171597 ; 2 : -3316406409.76059 ; 3 : -5705123085.24786 ; 4 : -14131339720.8167 ; 5 : -14172561092.3681 ; 6 : -26261201261.7151 ; 7 : -15574739437.8021 ; 8 : -23014032669.3972 ; 9 : -6502069505.27235 ; 10 : -7849571495.92278 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-22.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -7152914.17785539 ; 2 : -899812481.155632 ; 3 : -40879305.0143522 ; 4 : -1187298049.39919 ; 5 : -25143119.9087468 ; 6 : -430889410.822665 ; 7 : -4669710.06078191 ; 8 : -53924887.6615304 ; 9 : -249560.649671704 ; 10 : -2083856.47599957 ; Normalized w: 0 : 1 ; 1 : -7152914.17785539 ; 2 : -1272527014.44288 ; 3 : -100133438.324761 ; 4 : -5816548787.25959 ; 5 : -275429078.801557 ; 6 : -11561976160.6118 ; 7 : -331516527.402345 ; 8 : -10828031506.0183 ; 9 : -150334142.238856 ; 10 : -3969623522.48133 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-23.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0666527623858572 ; 2 : -18.8360112512122 ; 3 : 0.477117467186015 ; 4 : -28.861485359655 ; 5 : 0.284559239513281 ; 6 : -11.2479882203183 ; 7 : 0.05364623108289 ; 8 : -1.48182311010333 ; 9 : 0.00302767512853031 ; 10 : -0.0597102447593446 ; Normalized w: 0 : 1 ; 1 : 0.0666527623858572 ; 2 : -26.6381425724766 ; 3 : 1.16869434197483 ; 4 : -141.391824699924 ; 5 : 3.11719028855879 ; 6 : -301.815195248984 ; 7 : 3.80850459778771 ; 8 : -297.547719028286 ; 9 : 1.82385702242837 ; 10 : -113.744490016337 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-24.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -1.13483165329766 ; 2 : -3.14189240521057 ; 3 : -3.85556204061568 ; 4 : -4.81394735425755 ; 5 : -2.35539461777473 ; 6 : -1.86406141067735 ; 7 : -0.436853034827643 ; 8 : -0.246595549989843 ; 9 : -0.0237534508055248 ; 10 : -0.0100330687573344 ; Normalized w: 0 : 1 ; 1 : -1.13483165329766 ; 2 : -4.44330685096582 ; 3 : -9.44415967115228 ; 4 : -23.5834293331042 ; 5 : -25.8020552796295 ; 6 : -50.0180163421044 ; 7 : -31.0134888903544 ; 8 : -49.5159934554448 ; 9 : -14.3089652024829 ; 10 : -19.1124034694775 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-25.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 1.50510433909097 ; 2 : -3.64397245792185 ; 3 : 4.81169521394091 ; 4 : -5.47553289210348 ; 5 : 2.90126212491159 ; 6 : -2.08900027148297 ; 7 : 0.532758762679652 ; 8 : -0.271508175617894 ; 9 : 0.0285383088217531 ; 10 : -0.0108432259294952 ; Normalized w: 0 : 1 ; 1 : 1.50510433909097 ; 2 : -5.1533552709071 ; 3 : 11.7861980719472 ; 4 : -26.8245233109588 ; 5 : 31.7817342209889 ; 6 : -56.0537593446173 ; 7 : 37.8221201418991 ; 8 : -54.5184089800045 ; 9 : 17.1913407955528 ; 10 : -20.6557050377746 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-26.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.345757815160744 ; 2 : -4.37784867134509 ; 3 : 0.983155629773327 ; 4 : -6.70261562851948 ; 5 : 0.582526225317591 ; 6 : -2.69298081052719 ; 7 : 0.104848166218479 ; 8 : -0.367463138049622 ; 9 : 0.00547179228580678 ; 10 : -0.0155521724928187 ; Normalized w: 0 : 1 ; 1 : 0.345757815160744 ; 2 : -6.19121296503327 ; 3 : 2.4082296306893 ; 4 : -32.8359764637534 ; 5 : 6.38125507889563 ; 6 : -72.2602578532954 ; 7 : 7.44348139752256 ; 8 : -73.786012519414 ; 9 : 3.29618151290307 ; 10 : -29.6259701492 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-14-27.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-1-2" class="section level3"> <h3><span class="math inline">\(\lambda = 1\)</span></h3> <pre class="r"><code>CorNullPlot("friendly", L, lambda = 1, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.990193622763482 ; 2 : -5.06198921317001 ; 3 : 3.08726746712871 ; 4 : -6.63454555986282 ; 5 : 1.79513442315682 ; 6 : -2.42359996013425 ; 7 : 0.323704259987644 ; 8 : -0.311160663080113 ; 9 : 0.0170326428239071 ; 10 : -0.0124270992850921 ; Normalized w: 0 : 1 ; 1 : 0.990193622763482 ; 2 : -7.15873379785134 ; 3 : 7.56222999395997 ; 4 : -32.5025025938233 ; 5 : 19.6647123463403 ; 6 : -65.0320111335117 ; 7 : 22.9807227385935 ; 8 : -62.4805652709523 ; 9 : 10.2603826058368 ; 10 : -23.6728902429088 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -3.12684190211306 ; 2 : -17.6353975654966 ; 3 : -8.46737310674435 ; 4 : -20.254336932018 ; 5 : -4.64802228386959 ; 6 : -6.80704817888075 ; 7 : -0.790739086096404 ; 8 : -0.807908388025388 ; 9 : -0.0397126751314222 ; 10 : -0.029734876458029 ; Normalized w: 0 : 1 ; 1 : -3.12684190211306 ; 2 : -24.9402184149668 ; 3 : -20.7407435732884 ; 4 : -99.2255811237051 ; 5 : -50.9165330532411 ; 6 : -182.652269449122 ; 7 : -56.1369062515392 ; 8 : -162.226716806982 ; 9 : -23.9227256370203 ; 10 : -56.6431836286852 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -10.7940524339494 ; 2 : -26.247769705336 ; 3 : -28.248298873281 ; 4 : -28.3993929685435 ; 5 : -14.9756538800984 ; 6 : -8.69700899339039 ; 7 : -2.45772441408362 ; 8 : -0.908393242956987 ; 9 : -0.117273938365903 ; 10 : -0.0278007549535556 ; Normalized w: 0 : 1 ; 1 : -10.7940524339494 ; 2 : -37.1199518993318 ; 3 : -69.1939183411753 ; 4 : -139.128043555432 ; 5 : -164.050068870393 ; 6 : -233.365239721775 ; 7 : -174.481124623085 ; 8 : -182.403915541384 ; 9 : -70.6452597971797 ; 10 : -52.9587963842078 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.331063312897156 ; 2 : -3.1562793110714 ; 3 : -1.19059699958548 ; 4 : -3.87849247704236 ; 5 : -0.689041864478171 ; 6 : -1.46387307310445 ; 7 : -0.125483240535191 ; 8 : -0.191160642893188 ; 9 : -0.0067641794121115 ; 10 : -0.00793607331546585 ; Normalized w: 0 : 1 ; 1 : -0.331063312897156 ; 2 : -4.46365300835478 ; 3 : -2.91635513827306 ; 4 : -19.000655079954 ; 5 : -7.54807544480224 ; 6 : -39.2798364227168 ; 7 : -8.90842634937685 ; 8 : -38.3847524532686 ; 9 : -4.07470933902129 ; 10 : -15.1177509929509 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.951032913951243 ; 2 : -5.84897758568653 ; 3 : 2.90624068444014 ; 4 : -7.73953612586871 ; 5 : 1.70378526127289 ; 6 : -2.82906893276751 ; 7 : 0.306395914747298 ; 8 : -0.364262701586486 ; 9 : 0.016118466422511 ; 10 : -0.0145937977983201 ; Normalized w: 0 : 1 ; 1 : 0.951032913951243 ; 2 : -8.27170342769413 ; 3 : 7.1188067465953 ; 4 : -37.9158287084305 ; 5 : 18.6640324148799 ; 6 : -75.9118853604111 ; 7 : 21.7519521223296 ; 8 : -73.1433699779336 ; 9 : 9.70968711221761 ; 10 : -27.8003229539881 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0249702803783759 ; 2 : -0.145657076906457 ; 3 : -0.0157505623782447 ; 4 : -0.0847934620633242 ; 5 : -4.75765185936808e-05 ; 6 : -0.0371188234915361 ; 7 : -0.000870044588121193 ; 8 : -0.00566998863502667 ; 9 : 2.68712178291464e-05 ; 10 : -0.000297923943091384 ; Normalized w: 0 : 1 ; 1 : -0.0249702803783759 ; 2 : -0.205990213616732 ; 3 : -0.0385808409885771 ; 4 : -0.415401431158374 ; 5 : -0.000521174648826459 ; 6 : -0.996002550862689 ; 7 : -0.0617670383781483 ; 8 : -1.13852468203904 ; 9 : 0.0161870931517943 ; 10 : -0.567527517382724 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00196487934640798 ; 2 : -0.0460336617730664 ; 3 : -0.012293675176516 ; 4 : -0.00594223839628071 ; 5 : 0.00365133072737254 ; 6 : 0.00145804112996473 ; 7 : 0.000325135346931134 ; 8 : 1.87667642822963e-05 ; 9 : 7.09738813481104e-05 ; 10 : -3.22422762322365e-07 ; Normalized w: 0 : 1 ; 1 : -0.00196487934640798 ; 2 : -0.0651014288051664 ; 3 : -0.0301132312459841 ; 4 : -0.0291109040017239 ; 5 : 0.0399983240858737 ; 6 : 0.039123348967101 ; 7 : 0.0230823198330043 ; 8 : 0.00376833636057234 ; 9 : 0.0427543268053942 ; 10 : -0.000614196321214654 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.174535157389586 ; 2 : -1.31940719334627 ; 3 : 0.608000101526193 ; 4 : -1.69157445372129 ; 5 : 0.355179353621336 ; 6 : -0.653402655127321 ; 7 : 0.0662604334520652 ; 8 : -0.0887948633866882 ; 9 : 0.00369286851125707 ; 10 : -0.0038219020120779 ; Normalized w: 0 : 1 ; 1 : 0.174535157389586 ; 2 : -1.86592354712292 ; 3 : 1.48929001229954 ; 4 : -8.28698854708872 ; 5 : 3.8907948787702 ; 6 : -17.5326330425225 ; 7 : 4.70402412918216 ; 8 : -17.8298670617271 ; 9 : 2.22456633596294 ; 10 : -7.28049762663516 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.010384245552025 ; 2 : -0.122495494717022 ; 3 : -0.00452512868369771 ; 4 : 0.00477788548918738 ; 5 : -0.00662659651902575 ; 6 : -0.0018962703120297 ; 7 : -0.00136806854923071 ; 8 : -0.000301367963661958 ; 9 : -0.000152455470711193 ; 10 : -1.04691243707978e-05 ; Normalized w: 0 : 1 ; 1 : 0.010384245552025 ; 2 : -0.173234789958415 ; 3 : -0.0110842562954915 ; 4 : 0.0234067629959142 ; 5 : -0.0725907278591123 ; 6 : -0.0508822718569577 ; 7 : -0.0971232322319784 ; 8 : -0.0605142068337442 ; 9 : -0.0918384466827538 ; 10 : -0.0199430636614102 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -54.4330577997137 ; 2 : -75.3822582526047 ; 3 : -127.859373985824 ; 4 : -70.8745891606404 ; 5 : -62.1956911684788 ; 6 : -16.804005937536 ; 7 : -9.32467943951548 ; 8 : -1.05535708335353 ; 9 : -0.402535746802676 ; 10 : 1.2533478632639e-16 ; Normalized w: 0 : 1 ; 1 : -54.4330577997137 ; 2 : -106.606611983145 ; 3 : -313.190225096953 ; 4 : -347.213158345921 ; 5 : -681.319660652013 ; 6 : -450.898794847688 ; 7 : -661.986570192026 ; 8 : -211.914020486758 ; 9 : -242.485609392606 ; 10 : 2.38755366176433e-13 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 18.2167132280335 ; 2 : -37.2481635623401 ; 3 : 46.1255530784785 ; 4 : -38.2497706023594 ; 5 : 23.4756614518062 ; 6 : -10.7758172978181 ; 7 : 3.67072070506425 ; 8 : -0.98639919204478 ; 9 : 0.165296958584317 ; 10 : -0.0231442798200358 ; Normalized w: 0 : 1 ; 1 : 18.2167132280335 ; 2 : -52.6768580833527 ; 3 : 112.984069145934 ; 4 : -187.384841508578 ; 5 : 257.162986590174 ; 6 : -289.145519892473 ; 7 : 260.595318631629 ; 8 : -198.06738580545 ; 9 : 99.574097583713 ; 10 : -44.088486247804 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -7.17853175053795 ; 2 : -27.0506794832733 ; 3 : -18.2475960181493 ; 4 : -28.2131254788656 ; 5 : -9.6095878910105 ; 6 : -8.77280537330281 ; 7 : -1.55284600963663 ; 8 : -0.942375623132412 ; 9 : -0.0735891904070297 ; 10 : -0.0306917638899097 ; Normalized w: 0 : 1 ; 1 : -7.17853175053795 ; 2 : -38.2554377966527 ; 3 : -44.6972992769079 ; 4 : -138.215522944672 ; 5 : -105.267761124699 ; 6 : -235.399070016966 ; 7 : -110.241130606538 ; 8 : -189.227523325207 ; 9 : -44.329776478968 ; 10 : -58.4659976764417 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.221054473926752 ; 2 : -1.43221033522857 ; 3 : -0.750033598456729 ; 4 : -1.98498166157922 ; 5 : -0.452597605035338 ; 6 : -0.760018870400118 ; 7 : -0.0860219012244282 ; 8 : -0.103249684371707 ; 9 : -0.00468799688277602 ; 10 : -0.00443544626823974 ; Normalized w: 0 : 1 ; 1 : -0.221054473926752 ; 2 : -2.02545128025117 ; 3 : -1.83719960616251 ; 4 : -9.72438443930199 ; 5 : -4.95795835501337 ; 6 : -20.3934463007672 ; 7 : -6.10694916885158 ; 8 : -20.7323720798561 ; 9 : -2.82402690936123 ; 10 : -8.44926320113332 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 1.19624893178564 ; 2 : -2.78874517700335 ; 3 : 3.62922444518989 ; 4 : -3.54630222772657 ; 5 : 2.14075870122612 ; 6 : -1.2352662665503 ; 7 : 0.386386406860824 ; 8 : -0.148139424670228 ; 9 : 0.0208324224662385 ; 10 : -0.0052923077513501 ; Normalized w: 0 : 1 ; 1 : 1.19624893178564 ; 2 : -3.9438812513207 ; 3 : 8.88974805275061 ; 4 : -17.3732618632507 ; 5 : 23.4508366167402 ; 6 : -33.1456721078263 ; 7 : 27.4307137211259 ; 8 : -29.7461603940805 ; 9 : 12.549351696028 ; 10 : -10.0815337236181 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 173.100946298253 ; 2 : -132.056233792338 ; 3 : 346.270132417169 ; 4 : -96.7141880167721 ; 5 : 152.034197990412 ; 6 : -15.6177233256506 ; 7 : 21.0879731371861 ; 8 : -1.17392349241305e-13 ; 9 : 0.852421119433525 ; 10 : 0.0632963828889122 ; Normalized w: 0 : 1 ; 1 : 173.100946298253 ; 2 : -186.755716825037 ; 3 : 848.185137588027 ; 4 : -473.800823057374 ; 5 : 1665.45119503111 ; 6 : -419.067492119265 ; 7 : 1497.09757852145 ; 8 : -2.35721966474706e-11 ; 9 : 513.494407010491 ; 10 : 120.57587137007 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 5.3495265524959 ; 2 : -14.9487809688657 ; 3 : 14.7915257998395 ; 4 : -17.516684025336 ; 5 : 8.30244894568615 ; 6 : -5.8646959351151 ; 7 : 1.41827520328496 ; 8 : -0.674850522217663 ; 9 : 0.0713638273861906 ; 10 : -0.0236897651229084 ; Normalized w: 0 : 1 ; 1 : 5.3495265524959 ; 2 : -21.1407687871147 ; 3 : 36.2316907268197 ; 4 : -85.813875695269 ; 5 : 90.9487714017457 ; 6 : -157.366305339409 ; 7 : 100.687551084308 ; 8 : -135.50890939804 ; 9 : 42.9892284344425 ; 10 : -45.1276035355778 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00977765933816548 ; 2 : -0.145932485463695 ; 3 : -0.0113791478754545 ; 4 : 0.0112463330904812 ; 5 : -0.000710737922922955 ; 6 : -0.000368517744149794 ; 7 : -0.000430361315273652 ; 8 : -6.51178268932423e-05 ; 9 : -3.72003634967045e-05 ; 10 : 8.81824604196897e-10 ; Normalized w: 0 : 1 ; 1 : 0.00977765933816548 ; 2 : -0.206379700133572 ; 3 : -0.0278731060025389 ; 4 : 0.0550955550981134 ; 5 : -0.00778574385718541 ; 6 : -0.00988836872200579 ; 7 : -0.0305526225206233 ; 8 : -0.013075555866322 ; 9 : -0.0224093211193656 ; 10 : 1.67982379393173e-06 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0384872560271654 ; 2 : -20.0257032861721 ; 3 : 0.113946543302254 ; 4 : -22.2940309104237 ; 5 : 0.0899959890306396 ; 6 : -7.39771516628133 ; 7 : 0.0159779049132858 ; 8 : -0.863265886010817 ; 9 : 0.00077959307039399 ; 10 : -0.0312699095652114 ; Normalized w: 0 : 1 ; 1 : 0.0384872560271654 ; 2 : -28.320621183364 ; 3 : 0.27911088904447 ; 4 : -109.218000080748 ; 5 : 0.985856665541376 ; 6 : -198.501527879835 ; 7 : 1.13431872280534 ; 8 : -173.342414182985 ; 9 : 0.469623138452364 ; 10 : -59.5673310449011 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0424900126823913 ; 2 : -0.204862447943877 ; 3 : 0.00823062156162634 ; 4 : 0.0242143926329621 ; 5 : 0.00461118704563706 ; 6 : -0.00302938347417584 ; 7 : 0.00123143806005101 ; 8 : -5.90971996918201e-08 ; 9 : 0.000112710544350614 ; 10 : -1.61792155923727e-05 ; Normalized w: 0 : 1 ; 1 : -0.0424900126823913 ; 2 : -0.289719252303183 ; 3 : 0.0201608230919338 ; 4 : 0.11862581276433 ; 5 : 0.0505130232354205 ; 6 : -0.0812868885380598 ; 7 : 0.0874234297344866 ; 8 : -1.18666235189395e-05 ; 9 : 0.0678962930594794 ; 10 : -0.030820450223172 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.930400264415246 ; 2 : -3.70186603891747 ; 3 : 2.85944248854643 ; 4 : -4.60728914576893 ; 5 : 1.683640400931 ; 6 : -1.69847916780134 ; 7 : 0.303804292845106 ; 8 : -0.215579216554214 ; 9 : 0.0162110032605313 ; 10 : -0.00859144761394906 ; Normalized w: 0 : 1 ; 1 : 0.930400264415246 ; 2 : -5.23522915832545 ; 3 : 7.00417504577288 ; 4 : -22.5710150091945 ; 5 : 18.443356526339 ; 6 : -45.5749785308527 ; 7 : 21.5679652190377 ; 8 : -43.2879631301865 ; 9 : 9.76543086103208 ; 10 : -16.3662003277549 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-20.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.189357436074152 ; 2 : -2.18713998400049 ; 3 : 0.523457390283247 ; 4 : -2.73704853728455 ; 5 : 0.314494381158206 ; 6 : -1.05126845117824 ; 7 : 0.0578881914886824 ; 8 : -0.139964604172638 ; 9 : 0.00313233378949845 ; 10 : -0.00591258914801345 ; Normalized w: 0 : 1 ; 1 : 0.189357436074152 ; 2 : -3.09308302818197 ; 3 : 1.28220350828286 ; 4 : -13.4087446351564 ; 5 : 3.44511333537955 ; 6 : -28.2084926332256 ; 7 : 4.10965391215672 ; 8 : -28.1046694658186 ; 9 : 1.88690289943346 ; 10 : -11.2631331529029 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-21.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -5.29085254945192 ; 2 : -14.3122890576611 ; 3 : -14.7633316610083 ; 4 : -17.2110730605033 ; 5 : -8.31779378885616 ; 6 : -5.77119243820943 ; 7 : -1.43202147996183 ; 8 : -0.668110253268745 ; 9 : -0.0720887000158238 ; 10 : -0.0235738734129143 ; Normalized w: 0 : 1 ; 1 : -5.29085254945192 ; 2 : -20.2406332939483 ; 3 : -36.162629472946 ; 4 : -84.3166938479896 ; 5 : -91.1168657366576 ; 6 : -154.857343236828 ; 7 : -101.663439918799 ; 8 : -134.155474134604 ; 9 : -43.4258882409932 ; 10 : -44.9068366721439 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-22.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.011031824614049 ; 2 : -8.51372794977676 ; 3 : -0.410722731336789 ; 4 : -10.715802734123 ; 5 : -0.232420664177928 ; 6 : -3.89870034133524 ; 7 : -0.0444726298975924 ; 8 : -0.496342841465798 ; 9 : -0.00247893408959616 ; 10 : -0.0198482864164879 ; Normalized w: 0 : 1 ; 1 : -0.011031824614049 ; 2 : -12.0402295329292 ; 3 : -1.00606111753736 ; 4 : -52.4964977658445 ; 5 : -2.54604081201168 ; 6 : -104.613107845527 ; 7 : -3.15724351966102 ; 8 : -99.6648515785855 ; 9 : -1.49329804404798 ; 10 : -37.809813462342 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-23.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0666353041034338 ; 2 : -1.60032561962479 ; 3 : 0.0517533578936664 ; 4 : -2.07037521903444 ; 5 : 0.0166280812133002 ; 6 : -0.800999203808154 ; 7 : 0.00365296790993558 ; 8 : -0.109256481675998 ; 9 : 0.000232838623536709 ; 10 : -0.00472374471145179 ; Normalized w: 0 : 1 ; 1 : -0.0666353041034338 ; 2 : -2.26320219548651 ; 3 : 0.126769319315123 ; 4 : -10.1427257254747 ; 5 : 0.182151503371048 ; 6 : -21.4930640356589 ; 7 : 0.259334995203378 ; 8 : -21.9385274059344 ; 9 : 0.140260873641394 ; 10 : -8.99845470968976 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-24.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.188237567641041 ; 2 : -0.727450065306265 ; 3 : -0.827449304863473 ; 4 : -0.996064881386437 ; 5 : -0.518184044043969 ; 6 : -0.368364827100734 ; 7 : -0.0996552594120817 ; 8 : -0.0489492642681959 ; 9 : -0.00588586410791703 ; 10 : -0.00200580461455446 ; Normalized w: 0 : 1 ; 1 : -0.188237567641041 ; 2 : -1.02876974830531 ; 3 : -2.02682858493615 ; 4 : -4.87970142020524 ; 5 : -5.67642179724264 ; 6 : -9.88426552700637 ; 7 : -7.07482158584837 ; 8 : -9.82893425794854 ; 9 : -3.54561639890819 ; 10 : -3.82093933586174 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-25.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.318575961780774 ; 2 : -0.860139438027326 ; 3 : 1.03590672218289 ; 4 : -1.13605981347938 ; 5 : 0.637587012294198 ; 6 : -0.413538763943057 ; 7 : 0.122934836233099 ; 8 : -0.0531536223784576 ; 9 : 0.00710771583295954 ; 10 : -0.00209124180424253 ; Normalized w: 0 : 1 ; 1 : 0.318575961780774 ; 2 : -1.21642085879022 ; 3 : 2.53744289046714 ; 4 : -5.56553372061184 ; 5 : 6.98441578011712 ; 6 : -11.096409450095 ; 7 : 8.72750759132757 ; 8 : -10.6731626662902 ; 9 : 4.28165403652843 ; 10 : -3.98369213663598 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-26.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0620172351956328 ; 2 : -0.589578226923912 ; 3 : 0.113546479302921 ; 4 : -0.633477934320979 ; 5 : 0.0701074140159413 ; 6 : -0.254175761793915 ; 7 : 0.0137122611200663 ; 8 : -0.0357105237849158 ; 9 : 0.000780670980072819 ; 10 : -0.00161871095325211 ; Normalized w: 0 : 1 ; 1 : 0.0620172351956328 ; 2 : -0.833789524595679 ; 3 : 0.278130936381648 ; 4 : -3.10339540479743 ; 5 : 0.767988242097698 ; 6 : -6.82025137924784 ; 7 : 0.973473969516084 ; 8 : -7.170616266584 ; 9 : 0.470272466089517 ; 10 : -3.083548771297 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-15-27.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-10-2" class="section level3"> <h3><span class="math inline">\(\lambda = 10\)</span></h3> <pre class="r"><code>CorNullPlot("friendly", L, lambda = 10, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0195328556153761 ; 2 : -0.0594702211988415 ; 3 : 0.0327668711521069 ; 4 : -0.0169877651859634 ; 5 : 0.00795464094593129 ; 6 : -2.07582093003884e-11 ; 7 : 0.00224884250417521 ; 8 : -0.000339881382700872 ; 9 : 0.000129544930260427 ; 10 : 4.48933975887091e-13 ; Normalized w: 0 : 1 ; 1 : -0.0195328556153761 ; 2 : -0.0841035933767297 ; 3 : 0.080262114790184 ; 4 : -0.0832227131516528 ; 5 : 0.087138725658816 ; 6 : -5.57001205042042e-10 ; 7 : 0.159651980091913 ; 8 : -0.068247640000548 ; 9 : 0.0780372466481116 ; 10 : 8.55192711804991e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0358065026199347 ; 2 : -0.109813620241973 ; 3 : -0.0921611131009101 ; 4 : -0.00449357364221964 ; 5 : -0.0504514864252425 ; 6 : -1.94204096867876e-08 ; 7 : -0.0093778326270938 ; 8 : -8.94253451505833e-05 ; 9 : -0.0006100283237745 ; 10 : 9.25920346995506e-06 ; Normalized w: 0 : 1 ; 1 : -0.0358065026199347 ; 2 : -0.155299911079488 ; 3 : -0.22574770122416 ; 4 : -0.0220139250901157 ; 5 : -0.55266834349542 ; 6 : -5.21104274526629e-07 ; 7 : -0.665760072173299 ; 8 : -0.0179564667951614 ; 9 : -0.367478145760112 ; 10 : 0.0176382357984341 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0460601509345883 ; 2 : -0.126969252938243 ; 3 : -0.106549961827225 ; 4 : -0.00238883209912362 ; 5 : -0.0419417937955603 ; 6 : -0.00035906754302965 ; 7 : -0.00862519569198984 ; 8 : -1.54466744023286e-10 ; 9 : -0.000393557258811038 ; 10 : 3.5719540097369e-06 ; Normalized w: 0 : 1 ; 1 : -0.0460601509345883 ; 2 : -0.179561639509643 ; 3 : -0.260993038589726 ; 4 : -0.0117028394480691 ; 5 : -0.459449331281172 ; 6 : -0.00963479321673753 ; 7 : -0.612328150303908 ; 8 : -3.10166760367572e-08 ; 9 : -0.237077011151655 ; 10 : 0.00680436144311315 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.052220166264115 ; 2 : -0.21578873505685 ; 3 : -0.0244235984878817 ; 4 : 0.0211278222084139 ; 5 : -1.9126721069789e-05 ; 6 : -0.00287676898704295 ; 7 : -0.000720157379246019 ; 8 : -1.47354411958072e-09 ; 9 : -1.17986761712105e-05 ; 10 : 1.67359379171181e-11 ; Normalized w: 0 : 1 ; 1 : 0.052220166264115 ; 2 : -0.305171355724732 ; 3 : -0.0598253539779209 ; 4 : 0.103504767573713 ; 5 : -0.000209522731620656 ; 6 : -0.077191812127095 ; 7 : -0.0511261021440885 ; 8 : -2.95885310925008e-07 ; 9 : -0.00710746611729978 ; 10 : 3.18809733739997e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0197859117021518 ; 2 : -0.00406558148012681 ; 3 : 0.0104864413529932 ; 4 : -0.0241463436813757 ; 5 : 0.0095341067489564 ; 6 : -2.30755579411994e-08 ; 7 : 0.00132100603554299 ; 8 : -0.000272497380541538 ; 9 : 8.72209435131181e-05 ; 10 : -1.68394832766551e-11 ; Normalized w: 0 : 1 ; 1 : -0.0197859117021518 ; 2 : -0.00574960046812822 ; 3 : 0.0256864305324541 ; 4 : -0.118292442346494 ; 5 : 0.104440906641313 ; 6 : -6.19182194103084e-07 ; 7 : 0.0937821252027416 ; 8 : -0.0547170397522438 ; 9 : 0.052541479378089 ; 10 : -3.20782211689395e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0218574539676484 ; 2 : -0.0824037408603593 ; 3 : -0.00614002807237893 ; 4 : 0.00211489988953475 ; 5 : 0.00698604161515864 ; 6 : -2.35189922485386e-07 ; 7 : 0.000594880543450452 ; 8 : -1.74727509540128e-11 ; 9 : 0.000114857534915558 ; 10 : -1.99581782474016e-12 ; Normalized w: 0 : 1 ; 1 : -0.0218574539676484 ; 2 : -0.116536487914998 ; 3 : -0.015039935783693 ; 4 : 0.0103608511728573 ; 5 : 0.0765282516058443 ; 6 : -6.31080785160275e-06 ; 7 : 0.0422323290775984 ; 8 : -3.50850054643384e-09 ; 9 : 0.0691896299112644 ; 10 : -3.8019150910457e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00237432331769622 ; 2 : -0.0462398949391692 ; 3 : -0.0124993074733049 ; 4 : -0.00552754002397608 ; 5 : 0.00393970330098859 ; 6 : 0.00118301483874229 ; 7 : 0.000429658426868888 ; 8 : 2.74361575907938e-11 ; 9 : 7.80029473540958e-05 ; 10 : -7.39434057412163e-12 ; Normalized w: 0 : 1 ; 1 : -0.00237432331769622 ; 2 : -0.0653930865456801 ; 3 : -0.0306169254477536 ; 4 : -0.0270793051831058 ; 5 : 0.0431572873565804 ; 6 : 0.0317436191738246 ; 7 : 0.030502722394049 ; 8 : 5.50913672109759e-09 ; 9 : 0.04698860256217 ; 10 : -1.40857821132771e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0219431041356869 ; 2 : -0.0876866619950901 ; 3 : 0.0103921746392133 ; 4 : 0.00287985137303969 ; 5 : -0.00286862935053328 ; 6 : -1.43079259662589e-08 ; 7 : -0.000390282821116643 ; 8 : -5.56132021440079e-10 ; 9 : -3.40538734311794e-05 ; 10 : -1.77299089694446e-12 ; Normalized w: 0 : 1 ; 1 : -0.0219431041356869 ; 2 : -0.124007666632682 ; 3 : 0.0254555251839644 ; 4 : 0.0141083327980016 ; 5 : -0.0314242600881694 ; 6 : -3.8392194093107e-07 ; 7 : -0.027707331692391 ; 8 : -1.11670423635481e-07 ; 9 : -0.0205138905469334 ; 10 : -3.37744295286939e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0102699849664691 ; 2 : -0.118163058545407 ; 3 : -0.00428146303544641 ; 4 : 0.00897886931340816 ; 5 : -0.00607702256265007 ; 6 : -2.18022463958924e-08 ; 7 : -0.00118125633382797 ; 8 : -6.11416895527969e-11 ; 9 : -0.000134049780259931 ; 10 : 1.00710494016409e-12 ; Normalized w: 0 : 1 ; 1 : 0.0102699849664691 ; 2 : -0.1671077999664 ; 3 : -0.0104873997894313 ; 4 : 0.0439872965699679 ; 5 : -0.0665704468006259 ; 6 : -5.85015660040982e-07 ; 7 : -0.0838608805826161 ; 8 : -1.22771538248595e-08 ; 9 : -0.0807509467505956 ; 10 : 1.91847543538952e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.690852916751373 ; 2 : -0.770513800087517 ; 3 : -1.5951688203757 ; 4 : -0.476494992189659 ; 5 : -0.778618867408852 ; 6 : -0.0880627775922175 ; 7 : -0.123013457323572 ; 8 : -2.33870595579938e-09 ; 9 : -0.0057429502369907 ; 10 : 0.000532638661057973 ; Normalized w: 0 : 1 ; 1 : -0.690852916751373 ; 2 : -1.0896710660794 ; 3 : -3.90734966351781 ; 4 : -2.33433919171224 ; 5 : -8.52934234757905 ; 6 : -2.36297228380372 ; 7 : -8.73308913505404 ; 8 : -4.69608428888282e-07 ; 9 : -3.45952576631845 ; 10 : 1.01464519378883 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.108170384139922 ; 2 : -0.206147375474361 ; 3 : 0.348130623086922 ; 4 : -0.0689149401615465 ; 5 : 0.168482070248735 ; 6 : -0.012301961557552 ; 7 : 0.0290133584820416 ; 8 : -2.05835313635092e-11 ; 9 : 0.00150964681283809 ; 10 : 0.000108494336084961 ; Normalized w: 0 : 1 ; 1 : 0.108170384139922 ; 2 : -0.29153641424346 ; 3 : 0.852742390400132 ; 4 : -0.337612878100449 ; 5 : 1.84562860820805 ; 6 : -0.330096267591305 ; 7 : 2.05974412266513 ; 8 : -4.13314029522206e-09 ; 9 : 0.909404022590064 ; 10 : 0.206675302996705 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0637215144298066 ; 2 : -0.262073035099418 ; 3 : -0.117674346743829 ; 4 : -1.31362021474771e-08 ; 5 : -0.0677801757615273 ; 6 : -0.00976843860254607 ; 7 : -0.0113770055593337 ; 8 : -0.000159614148663148 ; 9 : -0.000668956679339544 ; 10 : 1.55414115533463e-14 ; Normalized w: 0 : 1 ; 1 : -0.0637215144298066 ; 2 : -0.370627240569877 ; 3 : -0.288242105337721 ; 4 : -6.4353984838743e-08 ; 5 : -0.742494624325068 ; 6 : -0.262114712991913 ; 7 : -0.807687270981434 ; 8 : -0.0320502666853735 ; 9 : -0.402976305422186 ; 10 : 2.96054711950034e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0204714511128345 ; 2 : -0.0019488370924672 ; 3 : -0.00517120655273784 ; 4 : -0.0115228121135017 ; 5 : 0.00619618674533238 ; 6 : -0.000185925539428495 ; 7 : 0.000897022879882511 ; 8 : -2.25200579835849e-12 ; 9 : 0.000144329328823017 ; 10 : -2.09476166451391e-13 ; Normalized w: 0 : 1 ; 1 : 0.0204714511128345 ; 2 : -0.00275607184702286 ; 3 : -0.0126668174087445 ; 4 : -0.0564500201600805 ; 5 : 0.0678758250186613 ; 6 : -0.00498890573898519 ; 7 : 0.0636823070958086 ; 8 : -4.52199175442281e-10 ; 9 : 0.0869432976595516 ; 10 : -3.99039726258398e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0121335548047993 ; 2 : -0.0663113142773513 ; 3 : 0.0687073217928708 ; 4 : -0.0161256952537096 ; 5 : 0.0495645889278382 ; 6 : -6.25991565418021e-11 ; 7 : 0.00810031746570205 ; 8 : -0.000443511317927794 ; 9 : 0.000584817950651624 ; 10 : 7.69983331647635e-06 ; Normalized w: 0 : 1 ; 1 : 0.0121335548047993 ; 2 : -0.0937783599898149 ; 3 : 0.16829787998574 ; 4 : -0.0789994502384182 ; 5 : 0.542952868184955 ; 6 : -1.67971163233944e-09 ; 7 : 0.575065492746343 ; 8 : -0.0890563658461515 ; 9 : 0.35229153751905 ; 10 : 0.0146677277462732 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 10.2719823637698 ; 2 : -7.20318460817093 ; 3 : 20.5304480391493 ; 4 : -5.14993400932367 ; 5 : 9.07432025323978 ; 6 : -0.832396689612991 ; 7 : 1.27984170747343 ; 8 : -2.59643563638919e-13 ; 9 : 0.0529876608783972 ; 10 : 0.00336478860889876 ; Normalized w: 0 : 1 ; 1 : 10.2719823637698 ; 2 : -10.1868413651525 ; 3 : 50.2891218866391 ; 4 : -25.2294210636972 ; 5 : 99.4041979345084 ; 6 : -22.3355469866453 ; 7 : 90.859747813815 ; 8 : -5.21360138024495e-11 ; 9 : 31.9195135846789 ; 10 : 6.40972358888335 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0804250190946633 ; 2 : -0.20913154981791 ; 3 : 0.103270453174378 ; 4 : 3.84587195093193e-09 ; 5 : 0.0748879788157968 ; 6 : -0.00542799485448755 ; 7 : 0.012861860087431 ; 8 : -0.000338450326123986 ; 9 : 0.000885476047793812 ; 10 : 6.65904652059143e-11 ; Normalized w: 0 : 1 ; 1 : 0.0804250190946633 ; 2 : -0.295756674072593 ; 3 : 0.252959915783209 ; 4 : 1.88408477917306e-08 ; 5 : 0.820356705667619 ; 6 : -0.145648385713839 ; 7 : 0.913101485235675 ; 8 : -0.0679602861204866 ; 9 : 0.53340653782257 ; 10 : 1.26850903648523e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00966818161582002 ; 2 : -0.144352607254812 ; 3 : -0.0107263199007162 ; 4 : 0.0118047643901818 ; 5 : -4.37703199769233e-05 ; 6 : -1.41492575058493e-06 ; 7 : -0.000264633093185441 ; 8 : -2.56939343985045e-09 ; 9 : -1.84313786140173e-05 ; 10 : 1.04972765882325e-10 ; Normalized w: 0 : 1 ; 1 : 0.00966818161582002 ; 2 : -0.204145414943672 ; 3 : -0.0262740105746155 ; 4 : 0.057831298579445 ; 5 : -0.000479479832011598 ; 6 : -3.79664419370737e-05 ; 7 : -0.018787085910402 ; 8 : -5.15930108054822e-07 ; 9 : -0.0111029743585896 ; 10 : 1.9996691973065e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00447501157548617 ; 2 : -0.167572985101847 ; 3 : 0.0132150369856437 ; 4 : -2.32228572015251e-09 ; 5 : 0.0122440938412845 ; 6 : -0.00467197615102844 ; 7 : 0.00164054685429511 ; 8 : -7.7293018796906e-05 ; 9 : 6.07882820999004e-05 ; 10 : 4.78949215975624e-13 ; Normalized w: 0 : 1 ; 1 : 0.00447501157548617 ; 2 : -0.236983988218376 ; 3 : 0.0323700975468345 ; 4 : -1.13768301026509e-08 ; 5 : 0.134127327861632 ; 6 : -0.125362275155489 ; 7 : 0.116467272935076 ; 8 : -0.0155203149978044 ; 9 : 0.0366185705145578 ; 10 : 9.12369971592623e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0434220236573529 ; 2 : -0.200385262367952 ; 3 : 0.0103381531632292 ; 4 : 0.0227892305136963 ; 5 : 0.00696555414161558 ; 6 : -0.00265351698638848 ; 7 : 0.00189670056127292 ; 8 : 3.18781806534009e-09 ; 9 : 0.000165032100099215 ; 10 : -4.78218419472237e-11 ; Normalized w: 0 : 1 ; 1 : -0.0434220236573529 ; 2 : -0.283387555740449 ; 3 : 0.0253232001326513 ; 4 : 0.111643972778441 ; 5 : 0.0763038225777278 ; 6 : -0.0712013323321804 ; 7 : 0.134652382141685 ; 8 : 6.40108787311978e-07 ; 9 : 0.0994145480985482 ; 10 : -9.10977847411613e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00291477779865538 ; 2 : -0.194376806506933 ; 3 : 0.0431939408090762 ; 4 : 0.0168149612240841 ; 5 : 0.0197021958887266 ; 6 : -0.00330098871309094 ; 7 : 0.00401295902122041 ; 8 : -1.55454575419173e-11 ; 9 : 0.000247924354977249 ; 10 : -1.48433368797897e-13 ; Normalized w: 0 : 1 ; 1 : 0.00291477779865538 ; 2 : -0.274890315972875 ; 3 : 0.105803114962216 ; 4 : 0.0823761500873819 ; 5 : 0.215826742412822 ; 6 : -0.0885748218651706 ; 7 : 0.284891828830192 ; 8 : -3.12150310068116e-09 ; 9 : 0.14934844613787 ; 10 : -2.82756801673994e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-20.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0224977140060591 ; 2 : -0.158381286470429 ; 3 : 0.0127132227896865 ; 4 : 0.013098081242688 ; 5 : 0.00569201257749691 ; 6 : -0.00245792671521922 ; 7 : 0.00139279701419496 ; 8 : -2.66567369529955e-10 ; 9 : 9.76562903258117e-05 ; 10 : 6.46192629315638e-12 ; Normalized w: 0 : 1 ; 1 : 0.0224977140060591 ; 2 : -0.223984963352579 ; 3 : 0.0311409088210544 ; 4 : 0.0641672313082098 ; 5 : 0.0623528737259636 ; 6 : -0.0659530946273154 ; 7 : 0.0988787790916838 ; 8 : -5.35263029913721e-08 ; 9 : 0.0588276824077534 ; 10 : 1.23095879727273e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-21.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0471633256581118 ; 2 : -0.0580469017988411 ; 3 : -0.065202196387677 ; 4 : -0.00992353133348181 ; 5 : -0.0468154044704704 ; 6 : -0.000377171005801114 ; 7 : -0.00749811376477714 ; 8 : -3.86046041338126e-10 ; 9 : -0.000452502905774796 ; 10 : 1.24095567127934e-10 ; Normalized w: 0 : 1 ; 1 : -0.0471633256581118 ; 2 : -0.0820907157776602 ; 3 : -0.159712111258549 ; 4 : -0.0486151764271023 ; 5 : -0.512837061344097 ; 6 : -0.0101205600973591 ; 7 : -0.532313271062148 ; 8 : -7.75174298854396e-08 ; 9 : -0.272585587069647 ; 10 : 2.36394726786745e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-22.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0565341807814713 ; 2 : -0.110894994292429 ; 3 : -0.025953693174393 ; 4 : 0.00036040577475903 ; 5 : 0.000968086367006428 ; 6 : -0.00342344857240058 ; 7 : -0.000682305062755083 ; 8 : -2.93638345418113e-12 ; 9 : -2.94916183019017e-05 ; 10 : -2.33817712705689e-13 ; Normalized w: 0 : 1 ; 1 : 0.0565341807814713 ; 2 : -0.15682920492764 ; 3 : -0.0635733052180175 ; 4 : 0.00176562049702414 ; 5 : 0.0106048548164529 ; 6 : -0.0918607647043476 ; 7 : -0.0484388542520623 ; 8 : -5.89621118085457e-10 ; 9 : -0.0177656098687214 ; 10 : -4.45408934357664e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-23.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.077141970314195 ; 2 : -0.0941861763202096 ; 3 : 0.00518987912704219 ; 4 : 0.00177463673695511 ; 5 : -0.01003843133676 ; 6 : -1.73298544241002e-08 ; 7 : -0.00158454069673423 ; 8 : -4.51728148651004e-05 ; 9 : -0.000121666159524278 ; 10 : -6.0880774132438e-13 ; Normalized w: 0 : 1 ; 1 : -0.077141970314195 ; 2 : -0.133199367940104 ; 3 : 0.0127125556879744 ; 4 : 0.00869390896867551 ; 5 : -0.109965505702203 ; 6 : -4.65008790389564e-07 ; 7 : -0.112491230177376 ; 8 : -0.00907062923607692 ; 9 : -0.0732911128242349 ; 10 : -1.15974279345258e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-24.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0741245213820646 ; 2 : -0.0114951117333178 ; 3 : -0.0117838281938442 ; 4 : -0.0199818298544024 ; 5 : -0.0147475947233081 ; 6 : -1.50088466727849e-10 ; 7 : -0.00208966218713219 ; 8 : -0.000109361186096124 ; 9 : -0.000215171106929808 ; 10 : 7.72261250350425e-14 ; Normalized w: 0 : 1 ; 1 : 0.0741245213820646 ; 2 : -0.0162565429142521 ; 3 : -0.0288643662915406 ; 4 : -0.0978905745407946 ; 5 : -0.161551805978 ; 6 : -4.02729617090624e-09 ; 7 : -0.148351298625606 ; 8 : -0.0219595518866355 ; 9 : -0.129618046103947 ; 10 : 1.47111207523129e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-25.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0127087577771728 ; 2 : -0.0307315829632796 ; 3 : 0.066735541246966 ; 4 : -0.0139685311010714 ; 5 : 0.0392617512938869 ; 6 : -1.02058089003322e-09 ; 7 : 0.00796781584094096 ; 8 : -3.71711478127709e-05 ; 9 : 0.000489681534400756 ; 10 : -6.19255410939076e-13 ; Normalized w: 0 : 1 ; 1 : 0.0127087577771728 ; 2 : -0.043461021419864 ; 3 : 0.163468023763527 ; 4 : -0.0684315473076443 ; 5 : 0.43009093661639 ; 6 : -2.73850589598182e-08 ; 7 : 0.56565881054462 ; 8 : -0.00746390724368038 ; 9 : 0.294981815206788 ; 10 : -1.17964498707065e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-26.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0218432423462418 ; 2 : -0.127406783722892 ; 3 : -0.00276965061268409 ; 4 : 0.00721483372468209 ; 5 : -0.00208423119359559 ; 6 : -1.46629812973078e-05 ; 7 : -0.00031832663788253 ; 8 : -2.86524629670372e-11 ; 9 : -4.75723339730603e-05 ; 10 : -4.25023139317261e-12 ; Normalized w: 0 : 1 ; 1 : 0.0218432423462418 ; 2 : -0.180180401479249 ; 3 : -0.00678423076686282 ; 4 : 0.0353453224089898 ; 5 : -0.0228316087957645 ; 6 : -0.00039344907520306 ; 7 : -0.0225989494415869 ; 8 : -5.75336890230431e-09 ; 9 : -0.0286573465470158 ; 10 : -8.09643980218632e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-16-27.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-100-2" class="section level3"> <h3><span class="math inline">\(\lambda = 100\)</span></h3> <pre class="r"><code>CorNullPlot("friendly", L, lambda = 100, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0143258263202469 ; 2 : -0.0536731314173197 ; 3 : 0.038023953951068 ; 4 : -0.00847336183440839 ; 5 : 0.0110188598000896 ; 6 : 7.45288780367749e-10 ; 7 : 0.00286984116034979 ; 8 : -2.13984115657199e-11 ; 9 : 0.000166121359692821 ; 10 : 3.84358623366705e-14 ; Normalized w: 0 : 1 ; 1 : -0.0143258263202469 ; 2 : -0.075905270385407 ; 3 : 0.093139285183201 ; 4 : -0.0415108258005476 ; 5 : 0.120705561409919 ; 6 : 1.99981965092424e-08 ; 7 : 0.20373851123343 ; 8 : -4.29676694120694e-09 ; 9 : 0.1000707128701 ; 10 : 7.32180478817837e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0393072898699236 ; 2 : -0.106024568009562 ; 3 : -0.097676191395372 ; 4 : -1.16203194074142e-07 ; 5 : -0.0533458972631849 ; 6 : 1.48537530479948e-10 ; 7 : -0.00990567552805969 ; 8 : -1.3037998426785e-11 ; 9 : -0.000640783026514746 ; 10 : -1.80297946645294e-13 ; Normalized w: 0 : 1 ; 1 : -0.0393072898699236 ; 2 : -0.14994138202387 ; 3 : -0.23925682893709 ; 4 : -5.69277063926509e-07 ; 5 : -0.58437502562799 ; 6 : 3.98568018435733e-09 ; 7 : -0.703233200753983 ; 8 : -2.61800930632923e-09 ; 9 : -0.386004631655817 ; 10 : -3.43456940677709e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0471983746972584 ; 2 : -0.124083434436633 ; 3 : -0.108707831296981 ; 4 : -6.08969419030976e-08 ; 5 : -0.0429310811444038 ; 6 : -3.60110788740957e-12 ; 7 : -0.00875809871058111 ; 8 : -2.30395448024539e-12 ; 9 : -0.000396989324508739 ; 10 : -1.47000281868042e-13 ; Normalized w: 0 : 1 ; 1 : -0.0471983746972584 ; 2 : -0.175480475846119 ; 3 : -0.266278717722159 ; 4 : -2.98332869117001e-07 ; 5 : -0.470286431217493 ; 6 : -9.66278643667014e-11 ; 7 : -0.621763328640716 ; 8 : -4.62630387978099e-10 ; 9 : -0.239144471119603 ; 10 : -2.80026855705051e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0539582788568558 ; 2 : -0.188930502346326 ; 3 : -0.0280893431400025 ; 4 : 0.0228113553937437 ; 5 : -0.00143603651187446 ; 6 : -2.15992130583009e-10 ; 7 : -0.000835287082532969 ; 8 : 2.55982035462218e-13 ; 9 : -6.74604681276957e-06 ; 10 : -1.23321182867123e-13 ; Normalized w: 0 : 1 ; 1 : 0.0539582788568558 ; 2 : -0.267188078764136 ; 3 : -0.0688045579029532 ; 4 : 0.111752362111914 ; 5 : -0.0157309918190936 ; 6 : -5.79567703906345e-09 ; 7 : -0.0592995002646907 ; 8 : 5.14007847796959e-11 ; 9 : -0.00406378634786777 ; 10 : -2.34919570501963e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0198056824607031 ; 2 : -4.36733024185824e-08 ; 3 : 0.0118046817897605 ; 4 : -0.0159309096998483 ; 5 : 0.0106919811267829 ; 6 : 2.79418474996273e-11 ; 7 : 0.00145209391072763 ; 8 : -8.53750690386395e-13 ; 9 : 8.26999067968149e-05 ; 10 : 1.07096655108757e-14 ; Normalized w: 0 : 1 ; 1 : -0.0198056824607031 ; 2 : -6.1763376593981e-08 ; 3 : 0.0289154469608378 ; 4 : -0.0780451998059671 ; 5 : 0.11712478495117 ; 6 : 7.49758445113191e-10 ; 7 : 0.103088441141013 ; 8 : -1.7143177806532e-10 ; 9 : 0.0498180284747919 ; 10 : 2.04012803278531e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0235595599950422 ; 2 : -0.0729352264288025 ; 3 : -0.00628596902629248 ; 4 : 3.04157194967634e-08 ; 5 : 0.00713729140052068 ; 6 : -9.14136055260368e-10 ; 7 : 0.000591096532765901 ; 8 : -8.65337464892552e-12 ; 9 : 0.000113159486957897 ; 10 : -2.51620231842176e-13 ; Normalized w: 0 : 1 ; 1 : -0.0235595599950422 ; 2 : -0.103145986390365 ; 3 : -0.0153974166533562 ; 4 : 1.49005985853384e-07 ; 5 : 0.0781851099910563 ; 6 : -2.45288443229482e-08 ; 7 : 0.0419636909682795 ; 8 : -1.73758383921104e-09 ; 9 : 0.0681667339397591 ; 10 : -4.79321681966505e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00601948530079037 ; 2 : -0.0391864584023975 ; 3 : -0.0145052145385332 ; 4 : -0.000819116183986385 ; 5 : 0.00523031517453755 ; 6 : 6.28472560300545e-09 ; 7 : 0.000921365819989283 ; 8 : -4.73469179333874e-11 ; 9 : 0.000109667614931986 ; 10 : -7.94626799060662e-13 ; Normalized w: 0 : 1 ; 1 : -0.00601948530079037 ; 2 : -0.0554180209340396 ; 3 : -0.0355303742290065 ; 4 : -0.00401283338164469 ; 5 : 0.0572952320791157 ; 6 : 1.68636884019043e-07 ; 7 : 0.0654104844057311 ; 8 : -9.5071856674691e-09 ; 9 : 0.0660632469256254 ; 10 : -1.5137171247037e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0213402106789018 ; 2 : -0.0761744254681988 ; 3 : 0.0121255607384809 ; 4 : 1.55458418155982e-08 ; 5 : -0.00177602006117852 ; 6 : -1.42757830930138e-10 ; 7 : -0.000122700667812524 ; 8 : -1.5321263092994e-11 ; 9 : -1.12211778175473e-05 ; 10 : 3.91795484859355e-13 ; Normalized w: 0 : 1 ; 1 : -0.0213402106789018 ; 2 : -0.107726905603105 ; 3 : 0.0297014366544035 ; 4 : 7.61587601404752e-08 ; 5 : -0.0194553250017836 ; 6 : -3.83059457136253e-09 ; 7 : -0.00871088328262191 ; 8 : -3.07648521262078e-09 ; 9 : -0.00675958387001233 ; 10 : 7.46347260769794e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.012072716551565 ; 2 : -0.104897706018627 ; 3 : -0.0016482914884409 ; 4 : 0.00478541280484129 ; 5 : -0.00410098052086091 ; 6 : -5.26902901614132e-11 ; 7 : -0.000661347566875882 ; 8 : -6.73707428243486e-11 ; 9 : -8.99845589277491e-05 ; 10 : 8.36113326500383e-13 ; Normalized w: 0 : 1 ; 1 : 0.012072716551565 ; 2 : -0.148347758513368 ; 3 : -0.0040374730940528 ; 4 : 0.023443639160884 ; 5 : -0.0449239907832961 ; 6 : -1.4138288466613e-09 ; 7 : -0.0469510196399583 ; 8 : -1.35279377949696e-08 ; 9 : -0.0542062680913063 ; 10 : 1.59274650944661e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0584372637118367 ; 2 : -0.159766679353171 ; 3 : -0.16731250025789 ; 4 : 1.39220148390215e-09 ; 5 : -0.0779966027443049 ; 6 : -1.93398400430519e-11 ; 7 : -0.0139452220243767 ; 8 : -4.19305968701226e-14 ; 9 : -0.000704665629971957 ; 10 : 1.44173986190974e-14 ; Normalized w: 0 : 1 ; 1 : -0.0584372637118367 ; 2 : -0.225944204756567 ; 3 : -0.40983025322111 ; 4 : 6.82036650941168e-09 ; 5 : -0.854409974636502 ; 6 : -5.18942364122839e-10 ; 7 : -0.990012553071007 ; 8 : -8.41959702958714e-12 ; 9 : -0.424487206562392 ; 10 : 2.74642929350048e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-10.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0221386594068507 ; 2 : -0.126212034230156 ; 3 : 0.147703321949132 ; 4 : -4.64299381569152e-08 ; 5 : 0.0667310601145318 ; 6 : -8.09802179093666e-11 ; 7 : 0.0122849862328433 ; 8 : -1.86170370637593e-11 ; 9 : 0.000680553494538148 ; 10 : -1.63034348561158e-12 ; Normalized w: 0 : 1 ; 1 : 0.0221386594068507 ; 2 : -0.178490770542984 ; 3 : 0.361797772089401 ; 4 : -2.27459314546842e-07 ; 5 : 0.731002138219247 ; 6 : -2.17292726493707e-09 ; 7 : 0.872147504253376 ; 8 : -3.73827137370018e-09 ; 9 : 0.409962171454664 ; 10 : -3.10570805847057e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-11.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0266335902894288 ; 2 : -0.206100134415379 ; 3 : -0.0345510138726153 ; 4 : 0.0208532427113095 ; 5 : -0.0236810318748696 ; 6 : -0.00133824194458075 ; 7 : -0.00375805926144087 ; 8 : -1.11422860372917e-12 ; 9 : -0.000261551522963531 ; 10 : -4.54941002885209e-13 ; Normalized w: 0 : 1 ; 1 : -0.0266335902894288 ; 2 : -0.291469605297147 ; 3 : -0.0846323540837305 ; 4 : 0.102159608250242 ; 5 : -0.259412706857298 ; 6 : -0.0359087995010887 ; 7 : -0.266795741043607 ; 8 : -2.23735327958657e-10 ; 9 : -0.157557386982741 ; 10 : -8.66635743485219e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-12.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0178736752577191 ; 2 : -3.33297894882455e-09 ; 3 : -0.00880754674749978 ; 4 : -0.00231436528917833 ; 5 : 0.00587465749135139 ; 6 : 1.77477113835265e-11 ; 7 : 0.00117617949938169 ; 8 : 5.66228379357175e-13 ; 9 : 0.000182044741821306 ; 10 : -3.47304260795654e-14 ; Normalized w: 0 : 1 ; 1 : 0.0178736752577191 ; 2 : -4.7135440325317e-09 ; 3 : -0.021573995417084 ; 4 : -0.0113380280737915 ; 5 : 0.0643536485125974 ; 6 : 4.76221069183346e-10 ; 7 : 0.0835004610910593 ; 8 : 1.13697756215357e-10 ; 9 : 0.109662882136274 ; 10 : -6.61594106403663e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-13.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0100670198787314 ; 2 : -0.0594193512782408 ; 3 : 0.0709943910956656 ; 4 : -0.00557919096143803 ; 5 : 0.0528734045042586 ; 6 : 1.0187436081768e-11 ; 7 : 0.00862078224168945 ; 8 : -3.25336915145547e-13 ; 9 : 0.000594887873495194 ; 10 : 2.78058579403743e-15 ; Normalized w: 0 : 1 ; 1 : 0.0100670198787314 ; 2 : -0.0840316524450992 ; 3 : 0.17390003278397 ; 4 : -0.0273323420661422 ; 5 : 0.579199126781554 ; 6 : 2.73357595143208e-10 ; 7 : 0.612014826414758 ; 8 : -6.53271340939651e-11 ; 9 : 0.358357610896768 ; 10 : 5.29685172727352e-12 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-14.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.755145536903475 ; 2 : -0.129582507148287 ; 3 : 1.57226278196186 ; 4 : -0.00209137058101707 ; 5 : 0.702090740033755 ; 6 : -4.93753339754975e-11 ; 7 : 0.105647798050886 ; 8 : -6.54990111273523e-12 ; 9 : 0.0047908673591942 ; 10 : -6.94806849648922e-13 ; Normalized w: 0 : 1 ; 1 : 0.755145536903475 ; 2 : -0.183257339055417 ; 3 : 3.85124155737532 ; 4 : -0.0102455815731196 ; 5 : 7.69101871463966 ; 6 : -1.32487923817161e-09 ; 7 : 7.50024962613405 ; 8 : -1.31520970530639e-09 ; 9 : 2.88599559254255 ; 10 : -1.32356601604461e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-15.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0665160046524072 ; 2 : -0.175168821097131 ; 3 : 0.0728023434800905 ; 4 : 0.0124016851804963 ; 5 : 0.0575773053199646 ; 6 : -2.94031619393901e-10 ; 7 : 0.00980624380949297 ; 8 : -3.50977049744981e-12 ; 9 : 0.000729953319692173 ; 10 : 5.7734017138962e-15 ; Normalized w: 0 : 1 ; 1 : 0.0665160046524072 ; 2 : -0.247726122500469 ; 3 : 0.178328593605059 ; 4 : 0.0607556012857036 ; 5 : 0.630727778482136 ; 6 : -7.88969626198929e-09 ; 7 : 0.696174248993846 ; 8 : -7.04756322605971e-10 ; 9 : 0.439720389952048 ; 10 : 1.09979893107673e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-16.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00942958186553758 ; 2 : -0.132501486906584 ; 3 : -0.0108467867194774 ; 4 : 0.00772879978537314 ; 5 : -8.97741269895399e-05 ; 6 : -1.55430447297507e-10 ; 7 : -0.000342598154157444 ; 8 : -1.53879911171855e-10 ; 9 : -3.1048509866871e-05 ; 10 : 2.7699282816659e-12 ; Normalized w: 0 : 1 ; 1 : 0.00942958186553758 ; 2 : -0.187385399817893 ; 3 : -0.0265690928115166 ; 4 : 0.0378632315965926 ; 5 : -0.000983426288650087 ; 6 : -4.1706365511651e-09 ; 7 : -0.0243220561624572 ; 8 : -3.08988409353853e-08 ; 9 : -0.018703473904123 ; 10 : 5.27654979559615e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-17.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0032146401682356 ; 2 : -0.134244654152846 ; 3 : -0.00784455575406555 ; 4 : 0.00571811237588096 ; 5 : 0.000394357992006668 ; 6 : -1.97183075993725e-10 ; 7 : -0.000394845955582022 ; 8 : 2.87313262419052e-13 ; 9 : -3.8687191410436e-05 ; 10 : -5.46254762403491e-14 ; Normalized w: 0 : 1 ; 1 : -0.0032146401682356 ; 2 : -0.189850610579041 ; 3 : -0.0192151588562743 ; 4 : 0.0280129152256039 ; 5 : 0.00431997535908988 ; 6 : -5.2909771432137e-09 ; 7 : -0.0280312821030894 ; 8 : 5.76920452221879e-11 ; 9 : -0.0233049791462286 ; 10 : -1.04058306273911e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-18.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0468977220545989 ; 2 : -0.176515694967991 ; 3 : 0.0086371603609139 ; 4 : 0.0214837985710809 ; 5 : 0.00421092325703564 ; 6 : -3.60972344649366e-09 ; 7 : 0.00118923411980044 ; 8 : 1.56066251015029e-11 ; 9 : 0.000117942469740798 ; 10 : -4.27039448710873e-13 ; Normalized w: 0 : 1 ; 1 : -0.0468977220545989 ; 2 : -0.249630889795445 ; 3 : 0.021156635710832 ; 4 : 0.105248688471765 ; 5 : 0.0461283531160309 ; 6 : -9.68590440760158e-08 ; 7 : 0.084427247202284 ; 8 : 3.13378544916739e-09 ; 9 : 0.0710479799012381 ; 10 : -8.13484930538227e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-19.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00251787185842929 ; 2 : -0.168618656858548 ; 3 : 0.03223575211743 ; 4 : 0.0179165970080232 ; 5 : 0.0123936722249901 ; 6 : -1.68320195603717e-11 ; 7 : 0.00246049593551517 ; 8 : 8.37815192347735e-14 ; 9 : 0.000147420124064493 ; 10 : -6.70767119436693e-15 ; Normalized w: 0 : 1 ; 1 : -0.00251787185842929 ; 2 : -0.238462791398494 ; 3 : 0.078961144162546 ; 4 : 0.0877730411934653 ; 5 : 0.135765876959047 ; 6 : -4.51650479227166e-10 ; 7 : 0.174677883126001 ; 8 : 1.68231955454474e-11 ; 9 : 0.0888051779362482 ; 10 : -1.27777174968143e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-20.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0191148249070555 ; 2 : -0.136481631225831 ; 3 : 0.00291643180343143 ; 4 : 0.0123743506241611 ; 5 : 0.000209611834436676 ; 6 : -1.01131666064357e-09 ; 7 : 0.000344121189713614 ; 8 : -6.05400685949404e-13 ; 9 : 2.84537029045289e-05 ; 10 : -3.62249356682074e-13 ; Normalized w: 0 : 1 ; 1 : 0.0191148249070555 ; 2 : -0.193014173894374 ; 3 : 0.00714376978803194 ; 4 : 0.0606216898549702 ; 5 : 0.00229618260082011 ; 6 : -2.71364735997254e-08 ; 7 : 0.0244301809608108 ; 8 : -1.21563492952842e-10 ; 9 : 0.017140374595509 ; 10 : -6.9006363146921e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-21.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0643220952335851 ; 2 : -0.0495756418883013 ; 3 : -0.104658478278025 ; 4 : -0.000897793483634867 ; 5 : -0.06719758684831 ; 6 : 8.1660347993526e-12 ; 7 : -0.0108335701580218 ; 8 : -6.15090891031505e-13 ; 9 : -0.000610394136711532 ; 10 : -3.84944645309717e-14 ; Normalized w: 0 : 1 ; 1 : -0.0643220952335851 ; 2 : -0.0701105451217874 ; 3 : -0.256359869037317 ; 4 : -0.00439827185860237 ; 5 : -0.736112682534638 ; 6 : 2.19117707015775e-10 ; 7 : -0.769107184687973 ; 8 : -1.23509270690709e-10 ; 9 : -0.367698509724466 ; 10 : -7.33296816011143e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-22.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0589721054760297 ; 2 : -0.0897555934468185 ; 3 : -0.0313298482559382 ; 4 : 1.10541952772606e-07 ; 5 : -0.00229180342357664 ; 6 : -9.74836814540392e-10 ; 7 : -0.00125037947131985 ; 8 : 9.60506762493466e-12 ; 9 : -6.5803675390294e-05 ; 10 : -4.62945221399911e-14 ; Normalized w: 0 : 1 ; 1 : 0.0589721054760297 ; 2 : -0.126933577551336 ; 3 : -0.0767421419458741 ; 4 : 5.41542758927443e-07 ; 5 : -0.0251054486492099 ; 6 : -2.61576166113801e-08 ; 7 : -0.088768136537738 ; 8 : 1.92868227214546e-09 ; 9 : -0.0396398194546198 ; 10 : -8.81883307058329e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-23.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0776287643820075 ; 2 : -0.0832306955092176 ; 3 : 0.00600127913755874 ; 4 : 2.47278681546533e-08 ; 5 : -0.00938702983166618 ; 6 : -9.24665827443709e-11 ; 7 : -0.00147181641348643 ; 8 : -4.79113522282634e-11 ; 9 : -0.000111377475592741 ; 10 : 1.2383289318526e-12 ; Normalized w: 0 : 1 ; 1 : -0.0776287643820075 ; 2 : -0.117705978394881 ; 3 : 0.0147000716910288 ; 4 : 1.21141318811436e-07 ; 5 : -0.10282975973555 ; 6 : -2.48113877596227e-09 ; 7 : -0.104488599939135 ; 8 : -9.62052317437975e-09 ; 9 : -0.0670932588129991 ; 10 : 2.35894348438433e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-24.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0753958788269554 ; 2 : -0.00407553005654872 ; 3 : -0.0113385924414496 ; 4 : -0.0132336109957749 ; 5 : -0.0156953345608941 ; 6 : 2.33497774479345e-11 ; 7 : -0.00209047158649764 ; 8 : -5.04696944617978e-13 ; 9 : -0.000181781026995448 ; 10 : 6.38545877212385e-15 ; Normalized w: 0 : 1 ; 1 : 0.0753958788269554 ; 2 : -0.00576366987983038 ; 3 : -0.0277737658829298 ; 4 : -0.0648311887882667 ; 5 : -0.171933775731842 ; 6 : 6.26540275596879e-10 ; 7 : -0.148408760280274 ; 8 : -1.01342342178179e-10 ; 9 : -0.10950402158597 ; 10 : 1.21639218610288e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-25.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0122895833972033 ; 2 : -0.0244580158176761 ; 3 : 0.0674670143136826 ; 4 : -0.00752437004938331 ; 5 : 0.0401583101667782 ; 6 : 1.03320569137854e-11 ; 7 : 0.00805046894626414 ; 8 : -1.97027692060111e-13 ; 9 : 0.000479828726098487 ; 10 : 4.52651873003537e-15 ; Normalized w: 0 : 1 ; 1 : 0.0122895833972033 ; 2 : -0.0345888576780932 ; 3 : 0.165259759537571 ; 4 : -0.0368617345137387 ; 5 : 0.439912246992669 ; 6 : 2.77238179279449e-10 ; 7 : 0.571526598929575 ; 8 : -3.95628465760705e-11 ; 9 : 0.289046530590748 ; 10 : 8.62275086247565e-12 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-26.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0240187003585077 ; 2 : -0.113626133688216 ; 3 : 0.000156192994302674 ; 4 : 0.00396861511292672 ; 5 : -0.000220000356935625 ; 6 : -1.26192135831622e-11 ; 7 : 0.000132645205657432 ; 8 : -6.8435261571628e-11 ; 9 : -1.49657441041091e-05 ; 10 : 8.64410998450281e-13 ; Normalized w: 0 : 1 ; 1 : 0.0240187003585077 ; 2 : -0.160691619301894 ; 3 : 0.000382593137438991 ; 4 : 0.0194421640243366 ; 5 : -0.0024099831630566 ; 6 : -3.38609032734473e-10 ; 7 : 0.0094168754341803 ; 8 : -1.37416914629723e-08 ; 9 : -0.00901529269865721 ; 10 : 1.64665190336291e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-17-27.png" width="672" style="display: block; margin: auto;" /></p> </div> </div> <div id="iid" class="section level2"> <h2>IID</h2> <div id="no-regularization-lambda-0-3" class="section level3"> <h3>No regularization: <span class="math inline">\(\lambda = 0\)</span></h3> <pre class="r"><code>CorNullPlot("iid", L, lambda = 0, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9902233 Unnormalized w: 0 : 1 ; 1 : -0.0405368510281718 ; 2 : -0.200589095951288 ; 3 : -0.120752088126515 ; 4 : -0.362460941188633 ; 5 : -0.0832233990756255 ; 6 : -0.165826806753714 ; 7 : -0.0178231676620004 ; 8 : -0.0259697707667603 ; 9 : -0.00113612103796531 ; 10 : -0.00129362995115145 ; Normalized w: 0 : 1 ; 1 : -0.0405368510281718 ; 2 : -0.283675819958469 ; 3 : -0.29578100128555 ; 4 : -1.77568871520219 ; 5 : -0.911666659719494 ; 6 : -4.44960014871631 ; 7 : -1.26531938251147 ; 8 : -5.21468858371236 ; 9 : -0.684393881594384 ; 10 : -2.46428866028979 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0230825311326855 ; 2 : -0.425056423146347 ; 3 : -0.113624582563346 ; 4 : -0.724398854107389 ; 5 : -0.0757983243687847 ; 6 : -0.317560886039965 ; 7 : -0.0153874489963285 ; 8 : -0.0481496570455215 ; 9 : -0.000992705709733054 ; 10 : -0.00231290478163741 ; Normalized w: 0 : 1 ; 1 : -0.0230825311326855 ; 2 : -0.601120558387361 ; 3 : -0.278322249516936 ; 4 : -3.54881512563988 ; 5 : -0.830329041557538 ; 6 : -8.52105273816511 ; 7 : -1.09240051104786 ; 8 : -9.66837440191504 ; 9 : -0.598001173520966 ; 10 : -4.40594701803701 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.613516326876289 ; 2 : -1.71966778986634 ; 3 : -2.04701724129729 ; 4 : -2.69287715555184 ; 5 : -1.28761408547499 ; 6 : -1.07449246583325 ; 7 : -0.246065256474665 ; 8 : -0.146087556394099 ; 9 : -0.0137289731568745 ; 10 : -0.00617882053884931 ; Normalized w: 0 : 1 ; 1 : -0.613516326876289 ; 2 : -2.43197751120514 ; 3 : -5.01414773585802 ; 4 : -13.1923499421988 ; 5 : -14.1051055995207 ; 6 : -28.8316583389743 ; 7 : -17.4689002698359 ; 8 : -29.3341485141565 ; 9 : -8.2702677929157 ; 10 : -11.7702882298752 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9980103 Unnormalized w: 0 : 1 ; 1 : -0.000902347084345419 ; 2 : -0.00929193336098981 ; 3 : 0.00122931259673249 ; 4 : -0.00142235077580944 ; 5 : 0.000175604808176825 ; 6 : -0.000642308271362263 ; 7 : -0.000466993246917224 ; 8 : -0.000443297294507876 ; 9 : -9.44602351401145e-05 ; 10 : -4.03200251011892e-05 ; Normalized w: 0 : 1 ; 1 : -0.000902347084345419 ; 2 : -0.0131407781797788 ; 3 : 0.00301118859637039 ; 4 : -0.00696806727196982 ; 5 : 0.00192365429289629 ; 6 : -0.0172349394873168 ; 7 : -0.0331532316831724 ; 8 : -0.0890133902845065 ; 9 : -0.0569023940438951 ; 10 : -0.0768072666770125 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9984696 Unnormalized w: 0 : 1 ; 1 : -0.0678345291419158 ; 2 : -0.127875725147021 ; 3 : -0.19815560637456 ; 4 : -0.192919650010789 ; 5 : -0.135583981859309 ; 6 : -0.0812520812583151 ; 7 : -0.0291786189131145 ; 8 : -0.011657730511468 ; 9 : -0.00193796793321842 ; 10 : -0.000534479727395144 ; Normalized w: 0 : 1 ; 1 : -0.0678345291419158 ; 2 : -0.180843584801212 ; 3 : -0.485380125289465 ; 4 : -0.945109407765496 ; 5 : -1.48524810601429 ; 6 : -2.18022212408315 ; 7 : -2.07147644940774 ; 8 : -2.34085370857247 ; 9 : -1.16742261774867 ; 10 : -1.01815231643507 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0114727533854214 ; 2 : -0.0498172438639265 ; 3 : 0.0118116253548837 ; 4 : -0.0876621303977918 ; 5 : 0.0122992521414138 ; 6 : -0.0418953150673728 ; 7 : 0.00296493266200861 ; 8 : -0.00727741873704751 ; 9 : 0.000167956994609338 ; 10 : -0.000404990350610407 ; Normalized w: 0 : 1 ; 1 : 0.0114727533854214 ; 2 : -0.0704522219124128 ; 3 : 0.0289324551523852 ; 4 : -0.429454978479825 ; 5 : 0.134731556765921 ; 6 : -1.124169269153 ; 7 : 0.21048933815953 ; 8 : -1.46129408487306 ; 9 : 0.101176490567831 ; 10 : -0.771482700789114 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0111350267594512 ; 2 : -0.0266795754280783 ; 3 : 0.00735902687801976 ; 4 : -0.04969029447569 ; 5 : 0.00444416788353204 ; 6 : -0.0257308218227747 ; 7 : 0.00117443324760944 ; 8 : -0.0045212416856049 ; 9 : 9.27190608304607e-05 ; 10 : -0.000277156676507209 ; Normalized w: 0 : 1 ; 1 : 0.0111350267594512 ; 2 : -0.0377306174087443 ; 3 : 0.0180258608545751 ; 4 : -0.243431733268157 ; 5 : 0.0486834199830098 ; 6 : -0.690430400551911 ; 7 : 0.0833764895133866 ; 8 : -0.907858125274839 ; 9 : 0.055853518964132 ; 10 : -0.527967100972262 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9978326 Unnormalized w: 0 : 1 ; 1 : 0.0180544709284733 ; 2 : -0.00245783703720842 ; 3 : -0.00904400112602128 ; 4 : -0.0121003298721484 ; 5 : -0.00431352381836661 ; 6 : -0.00603469856203478 ; 7 : -0.00120174108668015 ; 8 : -0.00101078435328561 ; 9 : -0.000126542717233364 ; 10 : -7.9486861087073e-05 ; Normalized w: 0 : 1 ; 1 : 0.0180544709284733 ; 2 : -0.00347590647212305 ; 3 : -0.0221531879919086 ; 4 : -0.0592792678122407 ; 5 : -0.0472522859531041 ; 6 : -0.16192795450116 ; 7 : -0.0853151537691429 ; 8 : -0.202963887321641 ; 9 : -0.0762287278738752 ; 10 : -0.151417776192143 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.014510857364203 ; 2 : -0.0378709798938841 ; 3 : -0.028495844643426 ; 4 : -0.0809425395645655 ; 5 : -0.0173478237591951 ; 6 : -0.0371667594137445 ; 7 : -0.00362382754798107 ; 8 : -0.00631923635224205 ; 9 : -0.000257740809238301 ; 10 : -0.00037179177859789 ; Normalized w: 0 : 1 ; 1 : -0.014510857364203 ; 2 : -0.0535576533862897 ; 3 : -0.0698002791660149 ; 4 : -0.396535840836449 ; 5 : -0.190035887930704 ; 6 : -0.997288806630154 ; 7 : -0.257266234728603 ; 8 : -1.26889258899406 ; 9 : -0.155261831253286 ; 10 : -0.70824138168125 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.008320705374618 ; 2 : -0.0081291496366805 ; 3 : -0.0096852017391271 ; 4 : -0.0138113022001979 ; 5 : -0.00332037463451784 ; 6 : -0.00558679643695842 ; 7 : -0.00152085258308833 ; 8 : -0.00102829757487779 ; 9 : -8.98800426631903e-05 ; 10 : -5.748078464503e-05 ; Normalized w: 0 : 1 ; 1 : -0.008320705374618 ; 2 : -0.0114963536667539 ; 3 : -0.0237238023167776 ; 4 : -0.067661286147727 ; 5 : -0.0363728817338679 ; 6 : -0.149909479313912 ; 7 : -0.107969822638604 ; 8 : -0.206480514307723 ; 9 : -0.0541433079932174 ; 10 : -0.109497500161639 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-18-10.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-1-3" class="section level3"> <h3><span class="math inline">\(\lambda = 1\)</span></h3> <pre class="r"><code>CorNullPlot("iid", L, lambda = 1, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9902233 Unnormalized w: 0 : 1 ; 1 : -0.0197501799658939 ; 2 : -0.0480028667210606 ; 3 : -0.0379275988314252 ; 4 : -0.0762234482638905 ; 5 : -0.0261218473505986 ; 6 : -0.033995638241429 ; 7 : -0.00603267327179404 ; 8 : -0.00516302161997914 ; 9 : -0.000418538277949043 ; 10 : -0.00024393677511157 ; Normalized w: 0 : 1 ; 1 : -0.0197501799658939 ; 2 : -0.067886305149712 ; 3 : -0.0929032643059713 ; 4 : -0.373417109363928 ; 5 : -0.286150500752588 ; 6 : -0.91219869655592 ; 7 : -0.428277316575674 ; 8 : -1.03672651333626 ; 9 : -0.252125457648748 ; 10 : -0.464685150649179 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00218244400583294 ; 2 : -0.0950816757643174 ; 3 : -0.0336218589432436 ; 4 : -0.135504581690652 ; 5 : -0.0236811368702788 ; 6 : -0.0565322409458715 ; 7 : -0.00504139993758648 ; 8 : -0.00857394331796279 ; 9 : -0.000382388078553011 ; 10 : -0.000416126261459722 ; Normalized w: 0 : 1 ; 1 : -0.00218244400583294 ; 2 : -0.134465795399059 ; 3 : -0.0823563986147782 ; 4 : -0.663834165902754 ; 5 : -0.259413857024379 ; 6 : -1.51691920410439 ; 7 : -0.3579038909913 ; 8 : -1.72163415453802 ; 9 : -0.230348750362903 ; 10 : -0.792695953314336 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.170195270010404 ; 2 : -0.486597915290635 ; 3 : -0.551898117003095 ; 4 : -0.676471730529319 ; 5 : -0.35279778951818 ; 6 : -0.260883986493315 ; 7 : -0.070447875520796 ; 8 : -0.0349150352172874 ; 9 : -0.00416576004253135 ; 10 : -0.00146605118681346 ; Normalized w: 0 : 1 ; 1 : -0.170195270010404 ; 2 : -0.688153371226491 ; 3 : -1.35186877666043 ; 4 : -3.3140211304287 ; 5 : -3.86470615114134 ; 6 : -7.00025193648227 ; 7 : -5.0013030255708 ; 8 : -7.01088342992012 ; 9 : -2.50943393355759 ; 10 : -2.79274093171165 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9980103 Unnormalized w: 0 : 1 ; 1 : -0.00128479518161606 ; 2 : -0.00832171681123837 ; 3 : 0.00140763563409998 ; 4 : 0.00161652795446755 ; 5 : 0.000646152140337805 ; 6 : 0.0013397558971381 ; 7 : -0.000308649891301932 ; 8 : -8.66346212930184e-08 ; 9 : -7.81111060511662e-05 ; 10 : -4.36195964604597e-06 ; Normalized w: 0 : 1 ; 1 : -0.00128479518161606 ; 2 : -0.0117686847766815 ; 3 : 0.00344798904730399 ; 4 : 0.00791933728678106 ; 5 : 0.00707824205686519 ; 6 : 0.0359494231110842 ; 7 : -0.0219119685838471 ; 8 : -1.73960938919487e-05 ; 9 : -0.0470537568441898 ; 10 : -0.00830927552568261 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9984696 Unnormalized w: 0 : 1 ; 1 : -0.0325775610993165 ; 2 : -0.0543974101114557 ; 3 : -0.0720847214087252 ; 4 : -0.0659493507450574 ; 5 : -0.0488700460508899 ; 6 : -0.0266000567192026 ; 7 : -0.0106871935286174 ; 8 : -0.00356002770595598 ; 9 : -0.000735016804039403 ; 10 : -0.000147615066641242 ; Normalized w: 0 : 1 ; 1 : -0.0325775610993165 ; 2 : -0.0769295551375921 ; 3 : -0.176570785702055 ; 4 : -0.323084516386456 ; 5 : -0.535344532167773 ; 6 : -0.713754420353845 ; 7 : -0.758715474872715 ; 8 : -0.714847889982522 ; 9 : -0.442770608714831 ; 10 : -0.281197984391246 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00673381506404109 ; 2 : -0.0138407751387194 ; 3 : -0.00392500107492052 ; 4 : -0.0137266308999818 ; 5 : -0.000357400315025183 ; 6 : -0.0054372337726941 ; 7 : -0.000124146427110371 ; 8 : -0.000995463543661852 ; 9 : -5.37901252722243e-05 ; 10 : -4.40677105680697e-05 ; Normalized w: 0 : 1 ; 1 : 0.00673381506404109 ; 2 : -0.0195738119149333 ; 3 : -0.00961424987343076 ; 4 : -0.067246483184952 ; 5 : -0.00391512429197491 ; 6 : -0.14589629190362 ; 7 : -0.0088135220108606 ; 8 : -0.199887493164919 ; 9 : -0.0324029142990219 ; 10 : -0.0839463861679815 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0111556935543884 ; 2 : -0.00308411410458595 ; 3 : 0.00432919802742235 ; 4 : -0.00431515761454924 ; 5 : 0.00192971775723357 ; 6 : -0.00277604341683021 ; 7 : 0.000651520347601133 ; 8 : -0.000371668518460222 ; 9 : 6.40150039107466e-05 ; 10 : -2.33385566220332e-05 ; Normalized w: 0 : 1 ; 1 : 0.0111556935543884 ; 2 : -0.00436159599461161 ; 3 : 0.0106043261626482 ; 4 : -0.0211398686306622 ; 5 : 0.0211389989051021 ; 6 : -0.0744890614622777 ; 7 : 0.0462533562806532 ; 8 : -0.0746304462040344 ; 9 : 0.0385623323067918 ; 10 : -0.0444585720823917 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9978326 Unnormalized w: 0 : 1 ; 1 : 0.0191703735008943 ; 2 : 0.00235392083903741 ; 3 : -0.00531344730659793 ; 4 : -0.00223273858618263 ; 5 : -0.00190779557192878 ; 6 : -0.000747781072324904 ; 7 : -0.000733454988207041 ; 8 : 9.39725292070835e-08 ; 9 : -9.8774216023983e-05 ; 10 : -1.00587465533097e-05 ; Normalized w: 0 : 1 ; 1 : 0.0191703735008943 ; 2 : 0.00332894677531937 ; 3 : -0.0130152346763305 ; 4 : -0.0109381405303411 ; 5 : -0.0208988533970773 ; 6 : -0.0200650717200741 ; 7 : -0.0520701387305429 ; 8 : 1.88695341071694e-05 ; 9 : -0.0595011155036459 ; 10 : -0.0191613181543815 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00790992082874686 ; 2 : 0.002662954886282 ; 3 : -0.0047311806006799 ; 4 : -0.00691435335304447 ; 5 : -0.00168321396850534 ; 6 : -0.0015471503714363 ; 7 : -0.000315470776571894 ; 8 : -0.000178408590570786 ; 9 : -4.0369240933949e-05 ; 10 : -1.71817234863898e-05 ; Normalized w: 0 : 1 ; 1 : -0.00790992082874686 ; 2 : 0.00376598691616771 ; 3 : -0.0115889783526202 ; 4 : -0.0338732752325218 ; 5 : -0.0184386851931633 ; 6 : -0.0415144008233474 ; 7 : -0.0223962034012286 ; 8 : -0.0358241606690066 ; 9 : -0.0243182377374899 ; 10 : -0.0327301685571348 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0074475785728308 ; 2 : -0.00345757783165271 ; 3 : -0.0061470003353478 ; 4 : -0.00440828057441714 ; 5 : -0.000604679039560331 ; 6 : -0.000693235748723768 ; 7 : -0.000867998410912082 ; 8 : -0.000110162462776587 ; 9 : -4.01317704379318e-05 ; 10 : -2.9061910493349e-11 ; Normalized w: 0 : 1 ; 1 : -0.0074475785728308 ; 2 : -0.00488975346248383 ; 3 : -0.0150570142703192 ; 4 : -0.0215960761006903 ; 5 : -0.00662392700035504 ; 6 : -0.0186014671029517 ; 7 : -0.0616217742067147 ; 8 : -0.0221204469671325 ; 9 : -0.0241751866460108 ; 10 : -5.53612232086703e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-19-10.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-10-3" class="section level3"> <h3><span class="math inline">\(\lambda = 10\)</span></h3> <pre class="r"><code>CorNullPlot("iid", L, lambda = 10, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9902233 Unnormalized w: 0 : 1 ; 1 : -0.0137879535328333 ; 2 : 0.00266974779862749 ; 3 : -0.012641051669197 ; 4 : 0.000579032181585961 ; 5 : -0.00750074964225723 ; 6 : -0.000349552094298496 ; 7 : -0.00189888638839369 ; 8 : -1.6651506183022e-10 ; 9 : -0.000142379793050877 ; 10 : -4.50587775942304e-12 ; Normalized w: 0 : 1 ; 1 : -0.0137879535328333 ; 2 : 0.00377559354493471 ; 3 : -0.0309641264016902 ; 4 : 0.00283666677907235 ; 5 : -0.0821665955452618 ; 6 : -0.00937946693434626 ; 7 : -0.134807560473347 ; 8 : -3.34359590518067e-08 ; 9 : -0.0857689066309411 ; 10 : -8.583431032433e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00435786450452107 ; 2 : -0.00264411653921755 ; 3 : -0.00827250497601338 ; 4 : -0.00208988507645332 ; 5 : -0.00599799001026069 ; 6 : -0.000115650745348266 ; 7 : -0.0011841001957846 ; 8 : -2.43441845706757e-12 ; 9 : -0.000124791375770825 ; 10 : 7.20910129199417e-14 ; Normalized w: 0 : 1 ; 1 : 0.00435786450452107 ; 2 : -0.00373934547025647 ; 3 : -0.0202634160858676 ; 4 : -0.0102383041167361 ; 5 : -0.0657046885662085 ; 6 : -0.00310323513896687 ; 7 : -0.0840627747533471 ; 8 : -4.88827346612446e-10 ; 9 : -0.0751737281498222 ; 10 : 1.37329122203215e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0213906544699513 ; 2 : -0.0064965131610548 ; 3 : -0.0539805647596282 ; 4 : -0.00450372706774079 ; 5 : -0.0306417865494322 ; 6 : -0.00167769276716086 ; 7 : -0.00647651477907918 ; 8 : -4.78139909125402e-11 ; 9 : -0.000386234643916067 ; 10 : -2.22787960891607e-13 ; Normalized w: 0 : 1 ; 1 : -0.0213906544699513 ; 2 : -0.00918745702049901 ; 3 : -0.132224839688352 ; 4 : -0.0220636665134521 ; 5 : -0.335663953907648 ; 6 : -0.045017220872777 ; 7 : -0.459786937793475 ; 8 : -9.60097317734063e-09 ; 9 : -0.232665902947581 ; 10 : -4.2439790852523e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9980103 Unnormalized w: 0 : 1 ; 1 : -0.00201772460477806 ; 2 : -0.00818676279956309 ; 3 : 0.000119339197742771 ; 4 : 5.07400940916174e-06 ; 5 : 0.000104861491893788 ; 6 : 0.000855148935229326 ; 7 : -0.000369237660837132 ; 8 : -9.6006144765198e-10 ; 9 : -7.66743893857349e-05 ; 10 : -4.6483395267771e-11 ; Normalized w: 0 : 1 ; 1 : -0.00201772460477806 ; 2 : -0.0115778309830737 ; 3 : 0.000292320140782892 ; 4 : 2.4857468005054e-05 ; 5 : 0.00114870009047746 ; 6 : 0.022946053800712 ; 7 : -0.0262132735252506 ; 8 : -1.92778808704044e-07 ; 9 : -0.0461882855937261 ; 10 : -8.85481228601559e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9984696 Unnormalized w: 0 : 1 ; 1 : -0.0215033313300145 ; 2 : -0.00856616298487061 ; 3 : -0.0293302173171465 ; 4 : -0.00176588048082007 ; 5 : -0.0180265368132136 ; 6 : -0.000937203111658442 ; 7 : -0.00377598139841106 ; 8 : -1.02576741739946e-11 ; 9 : -0.000257194015160242 ; 10 : 2.35019992082386e-12 ; Normalized w: 0 : 1 ; 1 : -0.0215033313300145 ; 2 : -0.0121143838707024 ; 3 : -0.0718440664719519 ; 4 : -0.00865101224949958 ; 5 : -0.197470816925887 ; 6 : -0.0251477983967112 ; 7 : -0.268068086549999 ; 8 : -2.05972462718213e-09 ; 9 : -0.154932445114829 ; 10 : 4.47699205568421e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00496843770093787 ; 2 : -0.00433655506640026 ; 3 : -0.00814842666690878 ; 4 : -0.000329110343349857 ; 5 : -0.00347406629700626 ; 6 : 1.16070217052422e-07 ; 7 : -0.000879552022845182 ; 8 : -6.97603471302503e-09 ; 9 : -0.000109013313833644 ; 10 : 2.10299078875745e-11 ; Normalized w: 0 : 1 ; 1 : 0.00496843770093787 ; 2 : -0.00613281498888101 ; 3 : -0.019959487540414 ; 4 : -0.00161230482055865 ; 5 : -0.0380564895427754 ; 6 : 3.11449074590844e-06 ; 7 : -0.0624419992864651 ; 8 : -1.40077665314452e-06 ; 9 : -0.0656690990721294 ; 10 : 4.00607325828848e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0109676444502299 ; 2 : -1.44818541486029e-05 ; 3 : 0.0037142436442326 ; 4 : -6.61719149982427e-06 ; 5 : 0.00148940248647299 ; 6 : -0.000265612498956955 ; 7 : 0.000544712261023606 ; 8 : 1.64490757863574e-10 ; 9 : 5.61722206339259e-05 ; 10 : -1.32019803446206e-11 ; Normalized w: 0 : 1 ; 1 : 0.0109676444502299 ; 2 : -2.04804345452633e-05 ; 3 : 0.00909800170874537 ; 4 : -3.24174854097032e-05 ; 5 : 0.0163155867809108 ; 6 : -0.00712713124009611 ; 7 : 0.0386707343405788 ; 8 : 3.30294820412995e-08 ; 9 : 0.033837877156362 ; 10 : -2.51489928999088e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9978326 Unnormalized w: 0 : 1 ; 1 : 0.0197279154849016 ; 2 : 0.00131792422353716 ; 3 : -0.00512442464768514 ; 4 : -0.00108226195876817 ; 5 : -0.00195757088089246 ; 6 : -0.000259976149216675 ; 7 : -0.000745269206970503 ; 8 : 7.39184063764335e-09 ; 9 : -9.6954899924885e-05 ; 10 : -9.08393227679978e-11 ; Normalized w: 0 : 1 ; 1 : 0.0197279154849016 ; 2 : 0.00186382631110628 ; 3 : -0.01255222561217 ; 4 : -0.00530197913401414 ; 5 : -0.0214441145876012 ; 6 : -0.00697589210612538 ; 7 : -0.0529088650598985 ; 8 : 1.48426982016632e-06 ; 9 : -0.0584051681835093 ; 10 : -1.73043545262948e-07 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00742374059343939 ; 2 : 0.00271226649645315 ; 3 : -0.00332761072202119 ; 4 : -0.00376944630255119 ; 5 : -0.000662021649749187 ; 6 : -6.14923846990956e-05 ; 7 : -3.58501190457403e-05 ; 8 : 1.49206710310614e-11 ; 9 : -1.64480673216069e-05 ; 10 : -4.64340318850247e-13 ; Normalized w: 0 : 1 ; 1 : -0.00742374059343939 ; 2 : 0.0038357240640542 ; 3 : -0.00815094833156624 ; 4 : -0.0184664401081422 ; 5 : -0.00725208382248828 ; 6 : -0.00165001382742895 ; 7 : -0.00254510597409862 ; 8 : 2.99604696498097e-09 ; 9 : -0.00990823711804553 ; 10 : -8.84540885312298e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00778028617573776 ; 2 : -0.00211826758992109 ; 3 : -0.00542800064313431 ; 4 : -0.00280486798956937 ; 5 : 0.000365025323946987 ; 6 : -8.79554711790981e-07 ; 7 : -0.000572064645063383 ; 8 : -6.24138534790182e-10 ; 9 : -1.22694277035174e-05 ; 10 : 4.09597720972399e-11 ; Normalized w: 0 : 1 ; 1 : -0.00778028617573776 ; 2 : -0.00299568275440178 ; 3 : -0.013295831899178 ; 4 : -0.0137409907406221 ; 5 : 0.00399865207972791 ; 6 : -2.36009295059384e-05 ; 7 : -0.0406125609754265 ; 8 : -1.25326023138838e-07 ; 9 : -0.0073910445897476 ; 10 : 7.80259469235692e-08 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-20-10.png" width="672" style="display: block; margin: auto;" /></p> </div> <div id="lambda-100-3" class="section level3"> <h3><span class="math inline">\(\lambda = 100\)</span></h3> <pre class="r"><code>CorNullPlot("iid", L, lambda = 100, rho)</code></pre> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9902233 Unnormalized w: 0 : 1 ; 1 : -0.0134899430951596 ; 2 : 1.25578990189511e-07 ; 3 : -0.0119886801444646 ; 4 : 1.19048130384211e-08 ; 5 : -0.00702900186585543 ; 6 : -7.66463299827262e-10 ; 7 : -0.00177773456643075 ; 8 : -9.22062335550194e-12 ; 9 : -0.000133357895330528 ; 10 : 5.05819082768219e-13 ; Normalized w: 0 : 1 ; 1 : -0.0134899430951596 ; 2 : 1.77595511075124e-07 ; 3 : -0.0293661490433743 ; 4 : 5.8321434854728e-08 ; 5 : -0.0769988575734984 ; 6 : -2.05663684880707e-08 ; 7 : -0.12620663433814 ; 8 : -1.85148647550599e-09 ; 9 : -0.0803341585769528 ; 10 : 9.63555481004764e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-1.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0042641276489915 ; 2 : -5.27098034943002e-09 ; 3 : -0.0083918204009518 ; 4 : -8.52076344525011e-10 ; 5 : -0.00610190484090151 ; 6 : -1.94653968302033e-11 ; 7 : -0.00121135815458939 ; 8 : -1.08163870997325e-13 ; 9 : -0.000126616634693547 ; 10 : 1.63685754758784e-14 ; Normalized w: 0 : 1 ; 1 : 0.0042641276489915 ; 2 : -7.45429189716602e-09 ; 3 : -0.0205556779954101 ; 4 : -4.1743045319644e-09 ; 5 : -0.0668430185022345 ; 6 : -5.22311406256123e-10 ; 7 : -0.0859978978615098 ; 8 : -2.1719132922876e-11 ; 9 : -0.0762732553984979 ; 10 : 3.11811696184068e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-2.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.0203572279310974 ; 2 : -2.99792271559574e-09 ; 3 : -0.0518605547470987 ; 4 : -8.57609743521251e-11 ; 5 : -0.0291946788546736 ; 6 : -4.19801342447367e-11 ; 7 : -0.00613247110857061 ; 8 : 5.17774964546258e-13 ; 9 : -0.000361745147925575 ; 10 : 5.70725611445673e-15 ; Normalized w: 0 : 1 ; 1 : -0.0203572279310974 ; 2 : -4.23970296334187e-09 ; 3 : -0.127031896908064 ; 4 : -4.20141254013243e-10 ; 5 : -0.319811683356476 ; 6 : -1.12644520650958e-09 ; 7 : -0.435362260150285 ; 8 : 1.03968387738229e-10 ; 9 : -0.217913547644629 ; 10 : 1.08719858501318e-11 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-3.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9980103 Unnormalized w: 0 : 1 ; 1 : -0.00302824675324517 ; 2 : -3.26334368255717e-06 ; 3 : -0.00144537428214117 ; 4 : -1.2565620634739e-08 ; 5 : -0.000735176889291692 ; 6 : 7.28988596753944e-09 ; 7 : -0.000564838893939966 ; 8 : -1.21283093383695e-10 ; 9 : -9.06898368249016e-05 ; 10 : -2.38358555415901e-12 ; Normalized w: 0 : 1 ; 1 : -0.00302824675324517 ; 2 : -4.61506489455691e-06 ; 3 : -0.00354042947858739 ; 4 : -6.15587177129955e-08 ; 5 : -0.00805345932043076 ; 6 : 1.9560816685968e-07 ; 7 : -0.0400995835337589 ; 8 : -2.43534518708488e-08 ; 9 : -0.0546311241246911 ; 10 : -4.5405897155646e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-4.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9984696 Unnormalized w: 0 : 1 ; 1 : -0.0222488666349984 ; 2 : -3.67963458333565e-08 ; 3 : -0.0305901424996169 ; 4 : -9.91810860074905e-11 ; 5 : -0.0181738670775706 ; 6 : -1.28727999626536e-10 ; 7 : -0.00369933523612707 ; 8 : 1.84444589209588e-12 ; 9 : -0.000244215680810886 ; 10 : -4.70743787109451e-15 ; Normalized w: 0 : 1 ; 1 : -0.0222488666349984 ; 2 : -5.20378913233036e-08 ; 3 : -0.0749302402830873 ; 4 : -4.85886105706888e-10 ; 5 : -0.199084739109718 ; 6 : -3.45413469327003e-09 ; 7 : -0.262626748816313 ; 8 : 3.70361795765185e-10 ; 9 : -0.147114358550837 ; 10 : -8.96739114182644e-12 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-5.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.00472727695854174 ; 2 : -1.65233452512046e-07 ; 3 : -0.00871970234241137 ; 4 : -7.26175856188191e-09 ; 5 : -0.00384432022731011 ; 6 : 3.96221835275131e-10 ; 7 : -0.000970206415293238 ; 8 : -2.5922457234301e-11 ; 9 : -0.000116338829610484 ; 10 : 1.44348638780645e-13 ; Normalized w: 0 : 1 ; 1 : 0.00472727695854174 ; 2 : -2.33675389500266e-07 ; 3 : -0.0213588214478591 ; 4 : -3.55752062237953e-08 ; 5 : -0.0421124181354227 ; 6 : 1.0631747494139e-08 ; 7 : -0.0688778227073985 ; 8 : -5.20518810179489e-09 ; 9 : -0.0700819547535723 ; 10 : 2.74975632219082e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-6.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : 0.0108754693780752 ; 2 : -2.93278647895105e-09 ; 3 : 0.00353567356114553 ; 4 : 4.41653225137319e-09 ; 5 : 0.00135438461270386 ; 6 : -9.53123097490072e-10 ; 7 : 0.000501786037775442 ; 8 : 1.31469423502094e-11 ; 9 : 5.21440900672862e-05 ; 10 : -3.73013804233255e-13 ; Normalized w: 0 : 1 ; 1 : 0.0108754693780752 ; 2 : -4.147586414077e-09 ; 3 : 0.00866059612185564 ; 4 : 2.16365008968194e-08 ; 5 : 0.014836540078316 ; 6 : -2.55749764429555e-08 ; 7 : 0.0356232748022994 ; 8 : 2.63988507253635e-09 ; 9 : 0.0314113505610895 ; 10 : -7.10569268348634e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-7.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 1 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 0.9978326 Unnormalized w: 0 : 1 ; 1 : 0.0196032252483651 ; 2 : 1.91789565403605e-07 ; 3 : -0.00513778634181481 ; 4 : -2.39821350258084e-08 ; 5 : -0.00170055627190666 ; 6 : -1.6507373024075e-09 ; 7 : -0.000620376748796571 ; 8 : 7.07028696197817e-11 ; 9 : -8.23539419523238e-05 ; 10 : -1.43905493238789e-12 ; Normalized w: 0 : 1 ; 1 : 0.0196032252483651 ; 2 : 2.71231404515421e-07 ; 3 : -0.0125849549448869 ; 4 : -1.17487987511518e-07 ; 5 : -0.0186286606086033 ; 6 : -4.42939298541335e-08 ; 7 : -0.0440423800975256 ; 8 : 1.41970235453092e-08 ; 9 : -0.0496096209064922 ; 10 : -2.74131466132265e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-8.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00722137943819359 ; 2 : 1.84856711876845e-07 ; 3 : -0.00167198383292764 ; 4 : -5.18706981932582e-08 ; 5 : 0.000950107383682747 ; 6 : -5.0267900036921e-10 ; 7 : 0.000424305135351643 ; 8 : 2.99813721087855e-11 ; 9 : 2.38144849516342e-05 ; 10 : -9.44569375784918e-13 ; Normalized w: 0 : 1 ; 1 : -0.00722137943819359 ; 2 : 2.6142686903193e-07 ; 3 : -0.00409550724885557 ; 4 : -2.54113486350776e-07 ; 5 : 0.0104079049219051 ; 6 : -1.34882929882463e-08 ; 7 : 0.0301226763974304 ; 8 : 6.02021174017547e-09 ; 9 : 0.0143457318803013 ; 10 : -1.79934887834958e-09 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-9.png" width="672" style="display: block; margin: auto;" /></p> <pre><code>Number of False Discoveries by BH at FDR = 0.05: 0 Number of False Discoveries by ASH at lfsr = 0.05: 0 pihat0 estimated by ASH: 1 Unnormalized w: 0 : 1 ; 1 : -0.00748162680537013 ; 2 : -3.31075201234638e-08 ; 3 : -0.00508832201391876 ; 4 : -9.34529107037692e-09 ; 5 : 0.000527168441275429 ; 6 : -3.15048135566165e-13 ; 7 : -0.000521174978479096 ; 8 : -1.99161817334975e-12 ; 9 : -6.02561900317788e-06 ; 10 : 1.48913603391889e-13 ; Normalized w: 0 : 1 ; 1 : -0.00748162680537013 ; 2 : -4.68211039751427e-08 ; 3 : -0.0124637925810718 ; 4 : -4.5782389240423e-08 ; 5 : 0.0057748409378278 ; 6 : -8.45362856772617e-12 ; 7 : -0.0369997530436507 ; 8 : -3.99913755302532e-10 ; 9 : -0.00362980407965978 ; 10 : 2.83671620214799e-10 ; </code></pre> <p><img src="figure/mosek_reg_4.rmd/unnamed-chunk-21-10.png" width="672" style="display: block; margin: auto;" /></p> </div> </div> <div id="session-information" class="section level2"> <h2>Session information</h2> <pre class="r"><code>sessionInfo()</code></pre> <pre><code>R version 3.4.3 (2017-11-30) Platform: x86_64-apple-darwin15.6.0 (64-bit) Running under: macOS High Sierra 10.13.4 Matrix products: default BLAS: /Library/Frameworks/R.framework/Versions/3.4/Resources/lib/libRblas.0.dylib LAPACK: /Library/Frameworks/R.framework/Versions/3.4/Resources/lib/libRlapack.dylib locale: [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8 attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] Rmosek_8.0.69 PolynomF_1.0-1 CVXR_0.95 REBayes_1.2 [5] Matrix_1.2-12 SQUAREM_2017.10-1 EQL_1.0-0 ttutils_1.0-1 loaded via a namespace (and not attached): [1] Rcpp_0.12.16 knitr_1.20 whisker_0.3-2 [4] magrittr_1.5 workflowr_1.0.1 bit_1.1-12 [7] lattice_0.20-35 R6_2.2.2 stringr_1.3.0 [10] tools_3.4.3 grid_3.4.3 R.oo_1.21.0 [13] git2r_0.21.0 scs_1.1-1 htmltools_0.3.6 [16] bit64_0.9-7 yaml_2.1.18 rprojroot_1.3-2 [19] digest_0.6.15 gmp_0.5-13.1 ECOSolveR_0.4 [22] R.utils_2.6.0 evaluate_0.10.1 rmarkdown_1.9 [25] stringi_1.1.6 Rmpfr_0.6-1 compiler_3.4.3 [28] backports_1.1.2 R.methodsS3_1.7.1</code></pre> </div> <!-- Adjust MathJax settings so that all math formulae are shown using TeX fonts only; 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